Protein Alignment Mkp and Dusp8

DIOPT Version :10

• Sequence 1: NP_001036572.1
• Gene: Mkp / 4379907
• FlyBaseID: FBgn0083992
• Length: 203
• Species: Drosophila melanogaster
• Sequence 2: NP_032774.1
• Gene: Dusp8 / 18218
• MGIID: 106626
• Length: 663
• Species: Mus musculus
• Alignment Length: 225
• Identity: 63/225 - (28%)
• Similarity: 98/225 - (43%)
• Gaps: 59/225 - (26%)

  Fly    22 TTPTGVRYIERSTS-----------SVCVEDIAHCSQQLDPREYGF---------VVDTKPDSVP 66
            |.|..|...::||.           |:.:..:..|...:.....||         :.:.||.::|
Mouse    81 TEPQDVVVYDQSTRDASVLAADSFLSILLSKLDGCFDSVAILTGGFATFSSCFPGLCEGKPATLP 145

  Fly    67 ACILSD---------------FLYLGSQ-DAVSADNIIKYKITHILSVGIQTPEVEW-------P 108
            :..||.               .|||||| |.::.|.:.:..|:::|:.....|:.::       .
Mouse   146 SMSLSQPCLPVPSVGLTRILPHLYLGSQKDVLNKDLMTQNGISYVLNASNSCPKPDFICESRFMR 210

  Fly   109 LPVNCTF----LPCLDLPETNLMNYILPASMEFIEDAHRSQGCVLVHCNAGVSRSPSVVIGYLMQ 169
            :|:|..:    ||.||            .|:|||:.|..|...|:|||.||:|||.::.|.|:|:
Mouse   211 IPINDNYCEKLLPWLD------------KSIEFIDKAKLSSCQVIVHCLAGISRSATIAIAYIMK 263

  Fly   170 RRDMCYEDAYNLVKSWRPCIQPNAGFIQQL 199
            ...|..:|||..||..||.|.||..|:.||
Mouse   264 TMGMSSDDAYRFVKDRRPSISPNFNFLGQL 293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkp	NP_001036572.1	DSP	66..201	CDD:350348	52/161 (32%)
Dusp8	NP_032774.1	DSP_MapKP	10..137	CDD:238723	9/55 (16%)
		DSP_DUSP8	150..300	CDD:350493	50/156 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	313..367
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	404..624