Protein Alignment Mkp and Dusp2

DIOPT Version :10

• Sequence 1: NP_001036572.1
• Gene: Mkp / 4379907
• FlyBaseID: FBgn0083992
• Length: 203
• Species: Drosophila melanogaster
• Sequence 2: NP_034220.2
• Gene: Dusp2 / 13537
• MGIID: 101911
• Length: 318
• Species: Mus musculus
• Alignment Length: 219
• Identity: 63/219 - (28%)
• Similarity: 90/219 - (41%)
• Gaps: 44/219 - (20%)

  Fly     2 ILLYELQRRMGNLRPTATVVTTPTGVRYIERSTSSVCVEDIAHC-------SQQLDPR----EYG 55
            :||..||..|.. .|| ||.....|.:..:.....:|.|..|..       :...|||    :.|
Mouse   113 LLLAALQHEMRG-GPT-TVCFLRGGFKSFQTYCPDLCSEAPAQALPPAGAENSNSDPRVPIYDQG 175

  Fly    56 FVVDTKPDSVPACILSDFLYLGS-QDAVSADNIIKYKITHILSVGIQTP-EVEW-----PLPVNC 113
            ..|:..|          :||||| ..:.....:....||.:|:|....| ..|.     .:||
Mouse   176 GPVEILP----------YLYLGSCNHSSDLQGLQACGITAVLNVSASCPNHFEGLFHYKSIPV-- 228

  Fly   114 TFLPCLDLPETNLMNYI---LPASMEFIEDAHRSQGCVLVHCNAGVSRSPSVVIGYLMQRRDMCY 175
                     |.|.|..|   ...::.||:....|.|.|||||.||:|||.::.:.||:|...:..
Mouse   229 ---------EDNQMVEISAWFQEAISFIDSVKNSGGRVLVHCQAGISRSATICLAYLIQSHRVRL 284

  Fly   176 EDAYNLVKSWRPCIQPNAGFIQQL 199
            ::|::.||..|..|.||..|:.||
Mouse   285 DEAFDFVKQRRGVISPNFSFMGQL 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mkp	NP_001036572.1	DSP	66..201	CDD:350348	44/144 (31%)
Dusp2	NP_034220.2	DSP_MapKP	12..147	CDD:238723	10/35 (29%)
		DSP_DUSP2	174..317	CDD:350489	47/156 (30%)