DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ephrin and efna5a

DIOPT Version :9

Sequence 1:	NP_651927.1	Gene:	Ephrin / 43799	FlyBaseID:	FBgn0040324	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	XP_001337388.4	Gene:	efna5a / 64256	ZFINID:	ZDB-GENE-001128-1	Length:	227	Species:	Danio rerio

Alignment Length:	231	Identity:	64/231 - (27%)
Similarity:	97/231 - (41%)	Gaps:	44/231 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   193 FVTLLTLICMETVLLSTMSS-CAKTFYMHWNTSNSIFRIDNTDHIIDV--NKGNLAFEFDQVHII 254
            |..|.:.:.|..:.|...|. .|..:.:.||.:|.  |....|:.|||  |        |.:.:.
Zfish     7 FYLLFSSLWMSVLGLDPASKVVADRYAVFWNRTNP--RFYRGDYHIDVCIN--------DYLDVY 61

  Fly   255 CPVYEPGTFENETEKYIIYNVSKVEYETCRITNADPRVIAICDKPQK---LMFFTITFRPFTPQP 316
            ||.|.....|..||:|::|.|:...|.:|..| |.......|::|..   .:.|:..|:.|||..
Zfish    62 CPHYMDTVPEERTERYVLYMVNYDGYSSCDHT-AKGFKRWECNRPHSPNGPLKFSEKFQLFTPFS 125

  Fly   317 GGLEFLPGNDYYFISTSSKDDLYRRIGGRCSTNNMKVVFKVCCAPEDNNKTTALSNSKSVTDTGG 381
            .|.||.||.:||:||::..::      ||.|...:||..:    |.:|     ...|....|...
Zfish   126 LGFEFRPGREYYYISSTLAEN------GRRSCLRLKVFVR----PTNN-----CDKSHDRVDKFD 175

  Fly   382 AINVN-IANNDE-----------SHVNSHGNNIAIG 405
            ..::| |.||::           |.|||.|....:|
Zfish   176 DRSINSIENNNDGTSHESAEPSRSDVNSAGRVQTVG 211

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ephrin	NP_651927.1	Ephrin_ectodomain	217..358	CDD:259861	44/145 (30%)
Ephrin	NP_651927.1	PigN	<557..>622	CDD:282796
efna5a	XP_001337388.4	Ephrin-A_Ectodomain	30..159	CDD:259896	44/145 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11304
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	2.010