Protein Alignment Ephrin and EFNA5

DIOPT Version :10

• Sequence 1: NP_651927.1
• Gene: Ephrin / 43799
• FlyBaseID: FBgn0040324
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_001953.1
• Gene: EFNA5 / 1946
• HGNCID: 3225
• Length: 228
• Species: Homo sapiens
• Alignment Length: 230
• Identity: 64/230 - (27%)
• Similarity: 101/230 - (43%)
• Gaps: 48/230 - (20%)

  Fly   194 VTLLTLICMETVLLSTMSS-------CAKTFYMHWNTSNSIFRIDNTDHIIDV--NKGNLAFEFD 249
            |.:|||:.:  ||...:.|       .|..:.::||:||.  |....|:.|||  |        |
Human     4 VEMLTLVFL--VLWMCVFSQDPGSKAVADRYAVYWNSSNP--RFQRGDYHIDVCIN--------D 56

  Fly   250 QVHIICPVYEPGTFENETEKYIIYNVSKVEYETCRITNADPRVIAICDKPQK---LMFFTITFRP 311
            .:.:.||.||....|::||:|::|.|:...|..|..|:...:... |::|..   .:.|:..|:.
Human    57 YLDVFCPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWE-CNRPHSPNGPLKFSEKFQL 120

  Fly   312 FTPQPGGLEFLPGNDYYFISTSSKDDLYRRIGGRCSTNNMKVVFKVCCAPEDNNKTTALSNSKSV 376
            |||...|.||.||.:|::||::..|:      ||.|...:||..:         .|.:...:..|
Human   121 FTPFSLGFEFRPGREYFYISSAIPDN------GRRSCLKLKVFVR---------PTNSCMKTIGV 170

  Fly   377 TDTGGAINVNIANN--------DESHVNSHGNNIA 403
            .|....:|..:.|:        .||...|.|.|.|
Human   171 HDRVFDVNDKVENSLEPADDTVHESAEPSRGENAA 205

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ephrin	NP_651927.1	Ephrin_ectodomain	217..358	CDD:259861	45/145 (31%)
EFNA5	NP_001953.1	Ephrin-A_Ectodomain	30..159	CDD:259896	45/145 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	186..205		5/18 (28%)