Protein Alignment Ephrin and EFNA3

DIOPT Version :10

• Sequence 1: NP_651927.1
• Gene: Ephrin / 43799
• FlyBaseID: FBgn0040324
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_004943.1
• Gene: EFNA3 / 1944
• HGNCID: 3223
• Length: 238
• Species: Homo sapiens
• Alignment Length: 221
• Identity: 56/221 - (25%)
• Similarity: 92/221 - (41%)
• Gaps: 52/221 - (23%)

  Fly   196 LLTLICMETVLLSTMS-----SCAKTFYMHWNTSNSIFRIDNTDHIIDVNKGNLAFEFDQVHIIC 255
            ||.|:.:...||..::     :......::||:||...|.:.....::||        |.:.|.|
Human     7 LLLLLLVPVPLLPLLAQGPGGALGNRHAVYWNSSNQHLRREGYTVQVNVN--------DYLDIYC 63

  Fly   256 PVYE-----------PGTFENETEKYIIYNVSKVEYETCRITNADPRVIAICDK---PQKLMFFT 306
            |.|.           ||   ...|:|::|.||:..|.||..:....|  ..|::   |...:.|:
Human    64 PHYNSSGVGPGAGPGPG---GGAEQYVLYMVSRNGYRTCNASQGFKR--WECNRPHAPHSPIKFS 123

  Fly   307 ITFRPFTPQPGGLEFLPGNDYYFISTSSKDDLYRRIGGRCSTNNMKVVFKVCCAPEDNNKTTALS 371
            ..|:.::....|.||..|::||:|||.:     ..:..:|.  .|||.  ||||      :|:.|
Human   124 EKFQRYSAFSLGYEFHAGHEYYYISTPT-----HNLHWKCL--RMKVF--VCCA------STSHS 173

  Fly   372 NSKSVT-----DTGGAINVNIANNDE 392
            ..|.|.     ..|..:.:|:..:.|
Human   174 GEKPVPTLPQFTMGPNVKINVLEDFE 199

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ephrin	NP_651927.1	Ephrin_ectodomain	217..358	CDD:259861	40/154 (26%)
EFNA3	NP_004943.1	Ephrin-A_Ectodomain	31..166	CDD:259896	40/156 (26%)