DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ephrin and Efna5

DIOPT Version :9

Sequence 1:NP_651927.1 Gene:Ephrin / 43799 FlyBaseID:FBgn0040324 Length:652 Species:Drosophila melanogaster
Sequence 2:NP_997537.1 Gene:Efna5 / 13640 MGIID:107444 Length:228 Species:Mus musculus


Alignment Length:225 Identity:63/225 - (28%)
Similarity:98/225 - (43%) Gaps:41/225 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   194 VTLLTLICMETVLLSTMSS--CAKTFYMHWNTSNSIFRIDNTDHIIDV--NKGNLAFEFDQVHII 254
            :|||.|:....|......|  .|..:.::||:||.  |....|:.|||  |        |.:.:.
Mouse     7 LTLLFLVLWMCVFSQDPGSKVVADRYAVYWNSSNP--RFQRGDYHIDVCIN--------DYLDVF 61

  Fly   255 CPVYEPGTFENETEKYIIYNVSKVEYETCRITNADPRVIAICDKPQK---LMFFTITFRPFTPQP 316
            ||.||....|::||:|::|.|:...|..|..|:...:... |::|..   .:.|:..|:.|||..
Mouse    62 CPHYEDSVPEDKTERYVLYMVNFDGYSACDHTSKGFKRWE-CNRPHSPNGPLKFSEKFQLFTPFS 125

  Fly   317 GGLEFLPGNDYYFISTSSKDDLYRRIGGRCSTNNMKVVFKVCCAPEDNNKTTALSNSKSVTDTGG 381
            .|.||.||.:|::||::..|:      ||.|...:||..:         .|.:...:..|.|...
Mouse   126 LGFEFRPGREYFYISSAIPDN------GRRSCLKLKVFVR---------PTNSCMKTIGVHDRVF 175

  Fly   382 AINVNIANN--------DESHVNSHGNNIA 403
            .:|..:.|:        .||...|.|.|.|
Mouse   176 DVNDKVENSLEPADDTVHESAEPSRGENAA 205

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
EphrinNP_651927.1 Ephrin_ectodomain 217..358 CDD:259861 45/145 (31%)
PigN <557..>622 CDD:282796
Efna5NP_997537.1 Ephrin-A_Ectodomain 30..159 CDD:259896 45/145 (31%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 186..205 5/18 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167843265
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3858
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11304
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.840

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