DRSC/TRiP Functional Genomics Resources

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Protein Alignment Ephrin and Efna4

DIOPT Version :9

Sequence 1:NP_651927.1 Gene:Ephrin / 43799 FlyBaseID:FBgn0040324 Length:652 Species:Drosophila melanogaster
Sequence 2:NP_031936.2 Gene:Efna4 / 13639 MGIID:106643 Length:206 Species:Mus musculus


Alignment Length:188 Identity:54/188 - (28%)
Similarity:79/188 - (42%) Gaps:41/188 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   196 LLTLICMETVLLSTMSSCAKTFY-MHWNTSNSIFRIDNTDHIIDVNKGNLAFEFDQVHIICPVYE 259
            ||..:....:|.|.:..|:...: ::||:||.  |:...|.:::     |.|. |.:.|.||.||
Mouse     6 LLRTVLWAALLGSRLPGCSSLRHPIYWNSSNP--RLLRGDAVVE-----LGFN-DYLDIFCPHYE 62

  Fly   260 -PGTFENETEKYIIYNVSKVEYETCRITNADPRVIAICDKPQKLMFFTITFRPF----------- 312
             ||..|. .|.:.:|.|....||.|....|:......|..|         |.||           
Mouse    63 SPGPPEG-PETFALYMVDWSGYEACTAEGANAFQRWNCSMP---------FAPFSPVRFSEKIQR 117

  Fly   313 -TPQPGGLEFLPGNDYYFISTSSKDDLYRRIGGRCSTNNMKVVFKVCCAPEDNNKTTA 369
             ||.|.|.|||||..||:||..:.:.     .|||    :::...|||....::..:|
Mouse   118 YTPFPLGFEFLPGETYYYISVPTPES-----PGRC----LRLQVSVCCKESGSSHESA 166

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
EphrinNP_651927.1 Ephrin_ectodomain 217..358 CDD:259861 45/154 (29%)
PigN <557..>622 CDD:282796
Efna4NP_031936.2 Ephrin-A_Ectodomain 27..155 CDD:259896 45/154 (29%)
Cell attachment site. /evidence=ECO:0000255 41..43 0/1 (0%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 161..180 1/6 (17%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167843266
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3858
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR11304
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
43.840

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