DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ephrin and Efna1

DIOPT Version :9

Sequence 1:	NP_651927.1	Gene:	Ephrin / 43799	FlyBaseID:	FBgn0040324	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	NP_034237.3	Gene:	Efna1 / 13636	MGIID:	103236	Length:	205	Species:	Mus musculus

Alignment Length:	208	Identity:	54/208 - (25%)
Similarity:	84/208 - (40%)	Gaps:	62/208 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   196 LLTLICMETVLLSTMSSCAKTFYMHWNTSNSIFRIDNTDHIIDVNKGNLAFEFDQVHIICPVYEP 260
            ||.|.|        ..:.|....:.||:||..||.::....:.:|        |.:.||||.||.
Mouse     8 LLGLCC--------SLAAADRHIVFWNSSNPKFREEDYTVHVQLN--------DYLDIICPHYED 56

  Fly   261 GTFENET-EKYIIYNVSKVEYETCRITNADPRVIAICDK------PQKLMFFTITFRPFTPQPGG 318
            .:..:.. |:|.:|.|...||..|:..:.| :|...|::      |:||   :..|:.|||...|
Mouse    57 DSVADAAMERYTLYMVEHQEYVACQPQSKD-QVRWNCNRPSAKHGPEKL---SEKFQRFTPFILG 117

  Fly   319 LEFLPGNDYYFISTSSKDDLYRRIGGRCSTNNMKVVFKVCCAPEDNNKTTALSNSKSVTDTGGAI 383
            .||..|:.||:||    ..:|.: ..:|.  .:||                            .:
Mouse   118 KEFKEGHSYYYIS----KPIYHQ-ESQCL--KLKV----------------------------TV 147

  Fly   384 NVNIANNDESHVN 396
            |..|.:|.::|||
Mouse   148 NGKITHNPQAHVN 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ephrin	NP_651927.1	Ephrin_ectodomain	217..358	CDD:259861	43/147 (29%)
Ephrin	NP_651927.1	PigN	<557..>622	CDD:282796
Efna1	NP_034237.3	Ephrin-A_Ectodomain	19..147	CDD:259896	43/174 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167843268
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3858
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11304
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.840