Protein Alignment Ephrin and Efna5

DIOPT Version :10

• Sequence 1: NP_651927.1
• Gene: Ephrin / 43799
• FlyBaseID: FBgn0040324
• Length: 652
• Species: Drosophila melanogaster
• Sequence 2: NP_001420729.1
• Gene: Efna5 / 116683
• RGDID: 620391
• Length: 278
• Species: Rattus norvegicus
• Alignment Length: 275
• Identity: 70/275 - (25%)
• Similarity: 108/275 - (39%)
• Gaps: 59/275 - (21%)

  Fly   162 IKNRNCLLSSPQPSPMR-----CKMMIPFPKFGATSFVTLLTLICMETVLL------STMSSC-- 213
            ::|.:.|...|..|.:|     ..:..|.|.....|...|||  ..:.::|      ...|||
  Rat     7 VRNGSSLPGLPFGSGIRKSDDLFSLQFPLPSPPPHSLQALLT--ATDPLMLLRPHPGVRPSSCEF 69

  Fly   214 ----AKTFYMHWNTSN---SIFRIDNTDHIIDV--NKGNLAFEFDQVHIICPVYEPGTFENETEK 269
                .:..|..|....   |..|....|:.|||  |        |.:.:.||.||....|::||:
  Rat    70 SPCQLRQRYDLWEVPGIPLSCLRFQRGDYHIDVCIN--------DYLDVFCPHYEDSVPEDKTER 126

  Fly   270 YIIYNVSKVEYETCRITNADPRVIAICDKPQK---LMFFTITFRPFTPQPGGLEFLPGNDYYFIS 331
            |::|.|:...|..|..|:...:... |::|..   .:.|:..|:.|||...|.||.||.:|::||
  Rat   127 YVLYMVNFDGYSACDHTSKGFKRWE-CNRPHSPNGPLKFSEKFQLFTPFSLGFEFRPGREYFYIS 190

  Fly   332 TSSKDDLYRRIGGRCSTNNMKVVFKVCCAPEDNNKTTALSNSKSVTDTGGAINVNIANN------ 390
            ::..|:      ||.|...:||..:         .|.:...:..|.|....:|..:.|:
  Rat   191 SAIPDN------GRRSCLKLKVFVR---------PTNSCMKTIGVHDRVFDVNDKVENSLEPADD 240

  Fly   391 --DESHVNSHGNNIA 403
              .||...|.|.|.|
  Rat   241 TVHESAEPSRGENAA 255

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ephrin	NP_651927.1	Ephrin_ectodomain	217..358	CDD:259861	44/148 (30%)
Efna5	NP_001420729.1	Ephrin-A_Ectodomain	92..209	CDD:259896	41/131 (31%)