DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ephrin and efnb3

DIOPT Version :9

Sequence 1:	NP_651927.1	Gene:	Ephrin / 43799	FlyBaseID:	FBgn0040324	Length:	652	Species:	Drosophila melanogaster
Sequence 2:	NP_001106481.1	Gene:	efnb3 / 100127666	XenbaseID:	XB-GENE-5902269	Length:	331	Species:	Xenopus tropicalis

Alignment Length:	319	Identity:	89/319 - (27%)
Similarity:	133/319 - (41%)	Gaps:	69/319 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   182 MIPFPKFGATSFVTLLTLICMETVLLSTMSSCAKTFYMHWNTSNSIFRIDNTDHIIDVNKGNLAF 246
            |.|....||.....||.|  .:..:||.:|...    ::||::|..|. |...:::....|
Frog     1 MFPREPPGALYVRVLLAL--WDLGILSALSLDP----IYWNSANQRFE-DAEGYVLYPQIG---- 54

  Fly   247 EFDQVHIICPVYEP-GTFENET-EKYIIYNV-SKVEYETCRITNADPRVIAICDKPQKLMFFTIT 308
              |::.::||..|| |.|.:.: |.|.:|.| :|.|..:|.|... |.::..||:|.:.:.|||.
Frog    55 --DRLDLLCPRSEPRGPFSSSSYEFYKLYLVGTKEEMLSCSILRT-PNLLLTCDRPSQDLRFTIK 116

  Fly   309 FRPFTPQPGGLEFLPGNDYYFISTS--SKDDLYRRIGGRCSTNNMKVVFKVCCAPEDNNKTTALS 371
            |:.|:|...|.||....|||.|:||  ::|.|....||.|.|..|||..||...|  |.......
Frog   117 FQEFSPNLWGHEFQSQRDYYIIATSDGTQDGLENLRGGVCETKGMKVTLKVGQNP--NGAPPPRR 179

  Fly   372 NSKSVTDTGGAINVNIANNDESH--VNSHGNNIAIGTN-----------IGINGGQ--------I 415
            .|.:..|:|  |:.::.|.|..:  ..:.||....|.|           .|..||.        :
Frog   180 PSSAGKDSG--ISPSVPNPDIPNFGAETSGNATKTGENGPLPISHVPLVAGAAGGAALLLLVFGV 242

  Fly   416 IG----------------GPQSAGIPINPLSGNNNING-IPTTINSNIDQFNRIPIQPN 457
            :|                .|.|.|...:|..|..|.|| .|:.|        .:|::|:
Frog   243 VGWICHRRRQAKHSDTRHPPLSLGSITSPKRGGGNNNGHEPSDI--------IMPLRPS 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ephrin	NP_651927.1	Ephrin_ectodomain	217..358	CDD:259861	50/145 (34%)
Ephrin	NP_651927.1	PigN	<557..>622	CDD:282796
efnb3	NP_001106481.1	Cupredoxin	28..168	CDD:327505	51/151 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	73	1.000	Domainoid score	I9055
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0001210
OrthoInspector	1	1.000	-	-		otm47820
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.000