Protein Alignment CG34124 and Eml2

DIOPT Version :9

• Sequence 1: NP_001036333.1
• Gene: CG34124 / 4379887
• FlyBaseID: FBgn0083960
• Length: 2003
• Species: Drosophila melanogaster
• Sequence 2: NP_001334511.1
• Gene: Eml2 / 72205
• MGIID: 1919455
• Length: 841
• Species: Mus musculus
• Alignment Length: 583
• Identity: 122/583 - (20%)
• Similarity: 209/583 - (35%)
• Gaps: 124/583 - (21%)

  Fly     8 DLLGEEEELENENDVSFPRDIVSVEHSFGY---DCKKLFNLVLVDSDTLVFASGNFLNYFSISRQ 69
            |.|.....|:..:::  |...:.::..:||   ||:.  ||.|:.:..:|:...:....:|:..|
Mouse   228 DELAPTYSLDTRSEL--PSSRLKLDWVYGYRGRDCRA--NLYLLPTGEVVYFVASVAVLYSVEEQ 288

  Fly    70 EISFQETVYGCGVGFITKNEHPDYTNLFTVGENGAR-------PTVFIYEYPSLN-VRVKLLNAA 126
            .   |....|..........|||...:.|....|..       |.|.:::..||: :.|..|...
Mouse   289 R---QRHYLGHNDDIKCLAVHPDMVTIATGQVAGTTKEGKPLPPHVRVWDSVSLSTLHVLGLGVF 350

  Fly   127 QN--CFTAGSYNKTGELFASQAGYPDFIITIWRWENAEVVLRAKSFQSDILFVHFSEHNPILLCS 189
            ..  |..|.|.:..|.|..:.....|.::::|.|.....|:.:|.....:|...|...:|.||.:
Mouse   351 DRAVCCVAFSKSNGGNLLCAVDESNDHVLSVWDWAKESKVVDSKCSNEAVLVATFHPTDPSLLIT 415

  Fly   190 SGLSHIKFWKMANTFTGLKLKGDLGRFGKTDFSD-IYAMYMLQDENVISGSDWGNMLLWQAGLIK 253
            .|.|||.||.:    .|..|....|.|.|.:... :..:..|:..:|::|...||:.:|..|..:
Mouse   416 CGKSHIYFWSL----EGGSLSKRQGLFEKHEKPKYVLCVTFLEGGDVVTGDSGGNLYVWGKGGNR 476

  Fly   254 -------------FEICRKGRKPCHTKPITRITMKNGE-VTTVGMDGYVRVW--YWETVDLADPP 302
                         |.:|               .:::|. |:..|.|..|.:|  .:..|...:.|
Mouse   477 ITQEVQGAHDGGVFALC---------------ALRDGTLVSGGGRDRRVVLWGSDYSKVQEVEVP 526

  Fly   303 EDDLFVEIDPIYE-----------------------FKI---ADVELRCMQKIHPFDESDFTHYA 341
            ||  |..:..:.|                       |.:   ..||.......|| ..:.|....
Mouse   527 ED--FGPVRTVAEGRGDTLYVGTTRNSILLGSVHTGFSLLVQGHVEELWGLATHP-SRAQFVTCG 588

  Fly   342 QDGNGGIWFCDIN------TYDVPQKPRKLYSCIGGKVLAAQMSPVSPHFLCM-SESGKLFVYQY 399
            ||....:|..:.:      :.:.|.:....:.  .|.|||  :..|:..:|.: :|:..|.....
Mouse   589 QDKLVHLWSSETHQPVWSRSIEDPARSAGFHP--SGSVLA--VGTVTGRWLLLDTETHDLVAIHT 649

  Fly   400 DEQRLILEKEFPAEGVDVIWLDTNISVKGTELVAAFKDGILRQMYLDLSNGERPKMTRVRAFKAH 464
            |..          |.:.|:    :.|..|..|.....|.::....:|  .|.| |::|:.....|
Mouse   650 DGN----------EQISVV----SFSPDGAYLAVGSHDNLVYVYTVD--QGGR-KVSRLGKCSGH 697

  Fly   465 TSPITALTVSRNSSLLLTGSADKSIFIYQ-------LSRDEHQMVDMRP----LGFVQFAAIP 516
            :|.||.|..:::|:..:|.|.|..|..:.       .|.|..:.|:...    |||..|...|
Mouse   698 SSFITHLDWAQDSTCFVTNSGDYEILYWDPVTCKQITSADTVRNVEWATATCVLGFGVFGIWP 760

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG34124	NP_001036333.1	WD40 repeat	90..124	CDD:293791	10/41 (24%)
		WD40 repeat	131..166	CDD:293791	8/34 (24%)
		WD40	135..493	CDD:295369	84/407 (21%)
		WD40	163..574	CDD:225201	87/415 (21%)
		WD40 repeat	174..217	CDD:293791	14/42 (33%)
		WD40 repeat	270..318	CDD:293791	13/73 (18%)
		WD40 repeat	323..370	CDD:293791	7/52 (13%)
		WD40 repeat	414..462	CDD:293791	10/47 (21%)
		WD40 repeat	468..511	CDD:293791	14/53 (26%)
Eml2	NP_001334511.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG2106
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900