Protein Alignment lobo and Drc7

DIOPT Version :10

• Sequence 1: NP_001036757.1
• Gene: lobo / 4379864
• FlyBaseID: FBgn0083946
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_001036180.2
• Gene: Drc7 / 330830
• MGIID: 2685616
• Length: 876
• Species: Mus musculus
• Alignment Length: 909
• Identity: 268/909 - (29%)
• Similarity: 428/909 - (47%)
• Gaps: 116/909 - (12%)

  Fly    43 DEMEGEFEAEMEEMG--------------SSEFS-----LSEGEPSLNIGKI-DLSFPETVEE-- 85
            :::|.|.|||.||..              |:|.|     ||:.|.....||: .:..|...:.
Mouse     6 EKVEEEEEAEREEAAERAERTEKLERVTKSAEVSREGTILSQDELRDLEGKLMAIEIPTQADHSV 70

  Fly    86 FENSP---QCYPPSYYTLSPKERLLLLYAENFRKQLVLSYPKRRAMVLALPNECKVQKFVCTTIR 147
            ...:|   ...||||.|.|.||..|||.|:||.:|.....|.|..:.|...|||.|.|||.||:|
Mouse    71 ISQAPVDVTKLPPSYTTNSLKEEHLLLVADNFSRQYSHLCPDRVPLFLHPLNECNVPKFVSTTLR 135

  Fly   148 PTAFIYTQLISSVEEIAKFVADFIQYEPLQDPINLPNRLISPETLLRKRKGNSYEMATLLVSMLI 212
            ||...|.:|. :.:..|:||:||:...||.||:..|..|.|..|:|:.:|||.::.:|||.||||
Mouse   136 PTLMPYPELY-NWDSCAQFVSDFLTMVPLVDPLKPPTHLYSSTTVLKCQKGNCFDFSTLLCSMLI 199

  Fly   213 GAGHPALVVSGVAREETILNDQLAVPYPYPIVEVEVEEVKPKVEKPGQKYKLRGLPDLKSHLEED 277
            |:|:.|..|:|....:..|.|......|..:...|:  ||.|.:...:||.::...||.|..|::
Mouse   200 GSGYDAYCVNGYGSLDLCLMDLTREVCPLTVKAKEI--VKKKEKTVPKKYSIKPPRDLTSKFEQE 262

  Fly   278 MAE--VHRQKEAEEKRIQDEIIRKQMEDLELLAVDRYHYRRSHAWVVIINNAPWSVKPKTTYTDV 340
            ..|  :...|:.|::|:::|  ..::.:.|....|..|..|.|:||:::...
Mouse   263 QEEKRIQEIKDLEQRRLKEE--EDRILEAEKAKPDPLHGLRVHSWVLVLAGK------------- 312

  Fly   341 NGDVVEAPPTAIFIEPSTGFICETGCKQYILVDSIWNEYNYYV--------CKQKHQRVSELRWD 397
                 ...|.:.||:|.|.....|..:.::.::|:||..||::        ||       :|.:|
Mouse   313 -----REVPESFFIDPLTARSYSTKDEHFLGIESLWNHKNYWINMQDCWNCCK-------DLIFD 365

  Fly   398 LRDTKDWEHMLPG-EPPEMRIYKMASDENVADEERDI------SEEKHLDCIGSWVERLHIGLAD 455
            |.|...||:||.| :.|.:.:.: ..:|.:.|::.|:      .|:|..|...|||.::.|...:
Mouse   366 LGDPVRWEYMLLGTDKPHLSLTE-EDEEGLDDDDDDVEDLGKEEEDKSFDMPSSWVSQIEITPEE 429

  Fly   456 FEQRFPSSEKKIQYKGAIHERFSPYSQRDGKVMQLTIFNNDECTIPKVRYEYYENRSDL--MRHV 518
            ||.|.||.:|.||||.|..|::|||...:|.|.:||.:.:.:||......|:|:||.|:  ::|:
Mouse   430 FETRCPSGKKVIQYKKAQLEKWSPYLNNNGLVCRLTTYEDQQCTKVLEIKEWYQNREDMLELKHI 494

  Fly   519 KYTYATDQFEEIFNKGRNDSLKSIEYFSD-PSQQRKVHFFSASRIDSLELMVVEPGSLILHYKDR 582
            ..|  |....:.|..|...:|....|.|. |...|.:.|:...|:|.|......|.::..:|:.|
Mouse   495 NKT--TGLHVDYFKPGHPQALCVHSYKSMLPEMDRVMEFYKKIRVDGLVKREETPMTMTEYYEGR 557

  Fly   583 SDKCWYKEFEFTPAGNVLK------------KVTEKFLKASANDVCSNDIATRTFLFQQNKIVLK 635
            ||...|:...|.|....|.            |:||:|.: :.......|:|.|.||..:.:|.|:
Mouse   558 SDFLAYRHVNFGPRVKKLSQSSVESNPRPMVKITERFSR-NPEKPADEDVAERLFLIVEERIQLR 621

  Fly   636 FHYTFGALTATVVEFTKPPRPD-YGKELIYDEKLTKIYKANPLDPTRTNLELYRLLCEQLQYEDH 699
            :|.....:||:..||.:....| .|.::|...::...|:..|::.|:..|..|..: .||:.|:.
Mouse   622 YHCRDDYITASKREFLRRMEVDSKGNKIIMTPEMCISYEVEPMEHTKKLLYQYETM-NQLKNEEK 685

  Fly   700 LRKN--FEKIFEDINNVFDLRKSEKAEPKLKFSIFDPLRNGAARAIR--MRQFEEEEELKKEIAS 760
            |.::  :|...| :..:..||:.|:....|..||:|..||..::..|  |.:...||.|::..|.
Mouse   686 LSRHQAWESELE-VLEILKLREEEEEAHTLTISIYDTKRNEKSKEYREAMERVLHEEHLRQVEAQ 749

  Fly   761 KPADFLAPYLVPYKHQEELTPEQSQNAYNACLNDLKSRFVSLLNNLQRHYEDLTSESKSLNRFLN 825
              .|:|||:|......|:||..|:....:.||:|.|.|.:...|.:|..:|..|.|.:...::..
Mouse   750 --LDYLAPFLAQLPPGEKLTRWQAVRLKDECLSDFKQRLIDKANLIQARFEKETQELQKKQQWYQ 812

  Fly   826 KFENQFNNYDYKRLVQQSKDLELNK--------RMVQQRLTLTHEESQKKYEVVKNSLLKDPRL 881
              |||..      |..:.::|.|:.        |:::|||....|.:..||..::..|.|||||
Mouse   813 --ENQVT------LTPEDENLYLSYCSQAMFRIRILEQRLNRHKELAPLKYLALEEKLYKDPRL 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lobo	NP_001036757.1	YebA	<160..228	CDD:440916	29/67 (43%)
Drc7	NP_001036180.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..40		9/33 (27%)
		Transglut_core	<174..>215	CDD:450180	18/40 (45%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	385..412		4/27 (15%)
		PRK10246	<688..>851	CDD:182330	47/173 (27%)