Protein Alignment lobo and Drc7

DIOPT Version :10

• Sequence 1: NP_001036757.1
• Gene: lobo / 4379864
• FlyBaseID: FBgn0083946
• Length: 897
• Species: Drosophila melanogaster
• Sequence 2: NP_001099639.1
• Gene: Drc7 / 291853
• RGDID: 1565601
• Length: 874
• Species: Rattus norvegicus
• Alignment Length: 922
• Identity: 278/922 - (30%)
• Similarity: 437/922 - (47%)
• Gaps: 126/922 - (13%)

  Fly    24 KFKEIDEQRRSQGSE-SDFADEMEGEFEA-EMEEMG--SSEFSLSEGEPSLNIGKIDLSFPETVE 84
            |.:|.:|..|.:.:| ::.|::.|...:| |:.:.|  .|:..|.:.|..|.  .|::..|.
  Rat     7 KVEEEEEAEREEAAERAERAEKAERVLKATEVSKEGIILSQDDLRDLEEKLM--AIEIPTPA--- 66

  Fly    85 EFENSPQC--------YPPSYYTLSPKERLLLLYAENFRKQLVLSYPKRRAMVLALPNECKVQKF 141
              ::|..|        .||||.|.|.||..|||.|:||.:|.....|.|..:.|...|||.|.||
  Rat    67 --DHSVICQVPVDVTKLPPSYTTNSLKEEHLLLVADNFSRQYSHLCPDRVPLFLHPLNECNVPKF 129

  Fly   142 VCTTIRPTAFIYTQLISSVEEIAKFVADFIQYEPLQDPINLPNRLISPETLLRKRKGNSYEMATL 206
            |.||:|||...|.:|. :.:..|:||:||:...||.||:..|..|.|..|:|:.:|||.::.:||
  Rat   130 VSTTLRPTLMPYPELY-NWDSCAQFVSDFLTMVPLVDPLKPPTHLYSSTTVLQCQKGNCFDFSTL 193

  Fly   207 LVSMLIGAGHPALVVSGVAREETILNDQLAVPYPYPIVEVEVEEVKPKVEKPG-QKYKLRGLPDL 270
            |.|||||:|:.|..|:|....:..|.|......|   :.|:.:|:..|.||.. :||.::...||
  Rat   194 LCSMLIGSGYDAYCVNGYGSLDLCLMDLTREVCP---LTVKAKEIVAKKEKVAPKKYAVKPPRDL 255

  Fly   271 KSHLEEDMAEVHRQ--KEAEEKRIQDEIIRKQMEDLELLAVDRYHYRRSHAWVVIINNAPWSVKP 333
            .|..|::..|...|  |:.|.||:::|  .:::.:.|....|..|..|.|:||::::..
  Rat   256 TSRFEQEQEEKRLQAIKDQELKRLKEE--EERLLEAEKAKPDPLHGLRVHSWVLVLSGK------ 312

  Fly   334 KTTYTDVNGDVVEAPPTAIFIEPSTGFICETGCKQYILVDSIWNEYNYYV--------CKQKHQR 390
                        ...|.:.||:|.||....|....::.::|:||..||::        ||
  Rat   313 ------------REVPESFFIDPFTGRSYGTKDDHFLGIESLWNHKNYWINMQDCWNCCK----- 360

  Fly   391 VSELRWDLRDTKDWEHMLPG-EPPEMRIYKMASDENVADEERD----ISEEKHLDCIGSWVERLH 450
              :|.:||.|...||:||.| :.|.:.:.. ..||.:.|:|.:    ..|:|..|...|||.::.
  Rat   361 --DLIFDLGDPVRWEYMLLGTDKPHLSLTD-DDDEGLDDDEDEDQGKEEEDKSFDMPPSWVAQIE 422

  Fly   451 IGLADFEQRFPSSEKKIQYKGAIHERFSPYSQRDGKVMQLTIFNNDECTIPKVRYEYYENRSDL- 514
            |...:||.|.||.:|.||||.|..|::|||...:|.|.:||.:.:.:||......|:|:||.|:
  Rat   423 ITPEEFETRCPSGKKVIQYKKAQLEKWSPYLNNNGLVCRLTTYEDLQCTKVLEIKEWYQNREDML 487

  Fly   515 -MRHVKYTYATDQFEEIFNKGRNDSLKSIEYFSD-PSQQRKVHFFSASRIDSLELMVVEPGSLIL 577
             ::|:..|  |....:.|..|...:|....|.|. |...|.:.|:...|:|.|......|.::..
  Rat   488 ELKHINKT--TGLHVDYFKPGHPQALCVHSYKSMLPEMDRVMEFYKMIRVDGLVKREETPMTMTE 550

  Fly   578 HYKDRSDKCWYKEFEFTPAGNVLK------------KVTEKFLKASANDVCSNDIATRTFLFQQN 630
            :|:.|||...|:...|.|....|.            |:||:|.: :.......|:|.|.||..:.
  Rat   551 YYQGRSDFLSYRHINFGPRVKKLTQNSADSNPRPVVKITEQFFR-NPEKPADEDVAERVFLIAEE 614

  Fly   631 KIVLKFHYTFGALTATVVEFTKPPRPD-YGKELIYDEKLTKIYKANPLDPTRTNLELYRLLCEQL 694
            :|.|::|.....:||...||.:....| .|.::|...::...|:..|::.|:      :||   .
  Rat   615 RIQLRYHCRDDYITANKREFLRRTEVDSKGNKIIMTPEMCISYEVEPMEHTK------KLL---Y 670

  Fly   695 QYED--HLRKNFEKIFE--------DINNVFDLRKSEKAEPKLKFSIFDPLRNGAARAIR--MRQ 747
            |||.  || ||.||:..        ::..:..||:.|:....|..||:|..||..::..|  |.:
  Rat   671 QYETMIHL-KNEEKLSRHQAWESELEVLEILKLREEEEEAHTLTISIYDTKRNEKSKEYREAMER 734

  Fly   748 FEEEEELKKEIASKPADFLAPYLVPYKHQEELTPEQSQNAYNACLNDLKSRFVSLLNNLQRHYED 812
            ...||.|::..|.  .|:|||:|......|:||..|:....:.||:|.|.|.:...|.:|..:|.
  Rat   735 VLHEEHLRQVEAQ--LDYLAPFLAQLPPGEKLTRWQAVRLKDECLSDFKQRLIDKANLIQARFEK 797

  Fly   813 LTSESKSLNRFLNKFENQFNNYDYKRLVQQSKDLELNK--------RMVQQRLTLTHEESQKKYE 869
            .|.|.:...::..  |||..      |..:.:||.|:.        |:::|||....|.:..||.
  Rat   798 ETQELQKKQQWYQ--ENQVT------LTPEDEDLYLSYCSQAMFRIRILEQRLNRHKELAPLKYL 854

  Fly   870 VVKNSLLKDPRL 881
            .::..|.|||||
  Rat   855 ALEEKLYKDPRL 866

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
lobo	NP_001036757.1	YebA	<160..228	CDD:440916	29/67 (43%)
Drc7	NP_001099639.1	Transglut_core	<174..>215	CDD:450180	18/40 (45%)
		PRK10246	<686..>868	CDD:182330	54/191 (28%)