DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment side-VI and si:ch211-74m13.1

DIOPT Version :9

Sequence 1:	NP_001036705.1	Gene:	side-VI / 4379854	FlyBaseID:	FBgn0083950	Length:	1087	Species:	Drosophila melanogaster
Sequence 2:	XP_001922015.4	Gene:	si:ch211-74m13.1 / 100149459	ZFINID:	ZDB-GENE-081104-12	Length:	328	Species:	Danio rerio

Alignment Length:	273	Identity:	62/273 - (22%)
Similarity:	103/273 - (37%)	Gaps:	50/273 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly   180 SPPPTVIWLMNGQLQNSVVDYTYDG-----------AINSKLVVRNLSRIHQHAVYT--CQASNF 231
            :||..|:...:....|.....|:||           ...:.|:...:|::....:..  |..:
Zfish    30 NPPKLVVRFNSSASANCNTSVTHDGMGWEATVGGVPLSKANLITWRVSQLTDWKIEPPFCYIN-- 92

  Fly   232 HKKYVATNITIDLYLRPLLVEISFNNQPMSADRKYEIECQAIGSRPPAKIT--WWMGNLELHGHS 294
            :.|.....:.:.:|..|..|.||..||.|:...:||::|......|...:|  |:.|...::
Zfish    93 YGKQCEVPLPVTIYKTPDSVSISTVNQIMTEGNQYELQCDIHNVAPAQNLTINWYKGETLVN--- 154

  Fly   295 QKVSEDGNVSTSV-----LSITPTREDHGKALSCRATNELVRNGIR------ETAMKLNVFFIPT 348
             :.:...|..:.|     |.|.|.|.|.|....|.....|...|.:      ...:.::|.:.|.
Zfish   155 -QTNFTDNTKSPVNKIIRLLIHPDRADDGAQYRCETELNLGVEGPQPPPKNTSKPLSIDVHYKPQ 218

  Fly   349 LQLDLGSNLNPEDIEEGDDVYFECKVHANPAAYKVVWKHNHQIIQHNQRAGVIVSSGDLALQGVT 413
                  .:.:.|:|.:.|.||..|.|.|||||. ..|...|   ...:.:..::.|..|:
Zfish   219 ------HSSSAENISQSDTVYLNCTVKANPAAV-YTWHSEH---LKEKISSPVIQSSPLS----- 268

  Fly   414 RHQAGNYTCTASN 426
               .|.|||||:|
Zfish   269 ---PGKYTCTATN 278

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
side-VI	NP_001036705.1	IG_like	35..140	CDD:214653
		Ig_3	157..230	CDD:290638	10/62 (16%)
		IG_like	165..242	CDD:214653	11/74 (15%)
		Ig	265..343	CDD:299845	18/90 (20%)
		IG_like	267..343	CDD:214653	17/88 (19%)
		IG_like	363..440	CDD:214653	21/64 (33%)
		IGc2	364..429	CDD:197706	21/63 (33%)
		IG_like	456..532	CDD:214653
		Ig_3	456..524	CDD:290638
		fn3	545..622	CDD:278470
si:ch211-74m13.1	XP_001922015.4	Ig2_ICAM-1_like	109..209	CDD:143232	25/103 (24%)
		Ig_2	217..281	CDD:290606	24/80 (30%)
		IG_like	230..281	CDD:214653	21/61 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910