Protein Alignment side-III and LOC1272555

DIOPT Version :10

• Sequence 1: NP_001036681.1
• Gene: side-III / 4379844
• FlyBaseID: FBgn0083949
• Length: 1689
• Species: Drosophila melanogaster
• Sequence 2: XP_061512385.1
• Gene: LOC1272555 / 1272555
• VectorBaseID: AGAMI1_000296
• Length: 1387
• Species: Anopheles gambiae
• Alignment Length: 1199
• Identity: 228/1199 - (19%)
• Similarity: 363/1199 - (30%)
• Gaps: 393/1199 - (32%)

  Fly    58 AVEAVLGRTASLPCDIEPEAKDDRVYMVLWFRESAGKPLYSFDVRGRPFEKALYWSDTNSFGPRA 122
            |.||..|...||.|...|.                          ..|.|  :.||.:.......
Mosquito   343 ASEARTGDVVSLQCQTAPS--------------------------NPPAE--IKWSVSGHHVKNT 379

  Fly   123 YFVTGQQP--AKLSVDNIQLDDEGVYRCRV--------DFQNSPTRNHRINLTVIVPPHQILV-- 175
            ...|.:.|  ..:::.||.:..|...|..|        ....:....|.:|  |::||.|.::
Mosquito   380 TSRTIENPDGGWITLSNISVPVEANKRSLVVICHGLNMQLTENVIATHTVN--VLLPPSQPVITG 442

  Fly   176 YDASGRDVAGAVGPLLEGDNIVLTCEVRGGRPEPTVTWMN-----GTRTLEAGSGVSMGRHVTVN 235
            |.......||:|..        |.|...||.|..|:||..     .|.|......||....:.||
Mosquito   443 YTEGTIIAAGSVQR--------LQCTSTGGNPLATLTWYKNDKKLNTPTKTTDKSVSSEISILVN 499

  Fly   236 RLEVAQISRSALNN--TYRCQASNTKLVAPVERSIRIEMLLKPTSVNLTNKLKV----FASNTQY 294
                      |.:|  .|||:|.|:....|:..|..:.:...|.:|    |:|:    .....:.
Mosquito   500 ----------ATDNQAKYRCEAHNSATEIPMSASRTLAVNFPPETV----KIKIIPPELKPGIEA 550

  Fly   295 NLTCIVAGSVPDTEIKWTQN-------NRPFKRGLLSTSQSNGRVISTLTFYP--QPEDDGTMLK 350
            .|.|..:.|.|...|.|.::       |...|.||.      |..:|:|....  ..:.||.:..
Mosquito   551 TLICDSSSSNPPATISWWRDGIAVDGMNNSSKPGLW------GGTVSSLELKVNISQDMDGNVYT 609

  Fly   351 CEGSNPRLQNSAIEDSLMMNVIYPPQVTLSLGSTLRPDDIKEGDDVYFECHIKSNPKEHRIMWSH 415
            |:.:|..||.: :.:::.:.|:|||:......||:..   .||:.:........||......|:.
Mosquito   610 CQSANEALQRN-VHEAIKLQVLYPPKFKPPPSSTVVG---AEGEPLTVAMVATGNPMSISYTWTK 670

  Fly   416 DGQPVTQNVSWGIIISTRSLV-LQRVGRIHSGFYACSAANDRGETQSAPVNLRIRYAPVCSSSSI 479
            ||.|:..:.....|:|...:: :.|:.|..:|.|.|.|.|.:|   ||.:|:          |.:
Mosquito   671 DGLPILSSAGAQRIVSEGPILNITRLNRNDTGIYTCEAVNSQG---SAMINI----------SVV 722

  Fly   480 TVIGASLE-----------EDVPIPCRVNSDP-PEIDFEW-------------TFSTSGEHFEVP 519
            ...|||::           |:..:.|.|...| .|....|             ||:....:..|.
Mosquito   723 VEYGASIQSISENVTVNPGEEAMLSCTVEGKPLTEEHIRWERIGYDMTIKTSTTFANGTSYLHVK 787

  Fly   520 S------GHYATIQDPTMT--TTSDV--------------------------------------- 537
            :      |::..|.|..:.  |:.||
Mosquito   788 NARREDVGNFRCIADNRVANPTSRDVLLIVKFAPEIDKSPVMLRAAAGFGERARLPCRAQAAPRP 852

  Fly   538 ------RRTVVESNETHFESYVE-------TVSELIYTPK-GERDYGTLACYGRNAIGKQSDPCV 588
                  ...|:..|:: .:.|||       |...::...: ...|||...|..||.:|...:...
Mosquito   853 KFYWSRSGQVLNVNQS-AKFYVEHKQIDALTYESILVVERVASNDYGLYECIARNELGNVKEKVR 916

  Fly   589 FQVVPAAKP-------------------------------------------------------- 597
            ..|.....|
Mosquito   917 LDVTSPPDPPVSLNVLNVTHDSVTLAWTPGFDGGMKANYRIRYRELNSDRYWYEDSQPNSYKLTI 981

  Fly   598 GALRNCTLRPY-VVTSASLNSSNQTTMHANQILPTQYGRHESNYPHMEYVRERHNSSGGNNNGTA 661
            |.||..||..: ::.|..|.||        :.||.....|..:.|..:..     ||.|:...|:
Mosquito   982 GGLRMNTLYVFSIMASNGLGSS--------RYLPDVTRAHTKDTPPSQPA-----SSLGSKTATS 1033

  Fly   662 PAAG---------------------------------RNNVANKNMRGRTSAGQAKSNNKQLTQQ 693
            .:.|                                 |..|..:..||.|.:..::.::...|.
Mosquito  1034 QSTGGTIGASGIVLLIGVAAGICLVLLNIILIGCCIHRRTVHKRIKRGETLSSVSEKSDAYSTD- 1097

  Fly   694 QLQRLKKRTSFTPSQTLAAIERQRQRKQLSQQQQQLQQQHHQATATKSGGDNKPDGSPAKSSKQR 758
                 ..|..:|...|      .:.......:...:....:|...|.....|..:|:.|::
Mosquito  1098 -----ANRPDYTDDTT------SKSASTYLVENGDMPPPRYQKEGTLPPYPNNINGAYART---- 1147

  Fly   759 MRRASRDPQIQQQQQHQQQQQHQLHAATSITSSQRKQAESNLSTSHLGKGSSSSSRSRRSSSSNI 823
            :.....:|...||:.|..|...:                                      ||.:
Mosquito  1148 LPHPRHNPVNYQQRSHDDQMIER--------------------------------------SSYV 1174

  Fly   824 NSKSNNGKQPAKYFNKRQKNMHKQKH------QQKLKQLKGTTNEHNSNIIHHYAALSSSLRRRK 882
            .:.|     |...|:....||:..::      ||....::.:|..  ..:|......:.:|.|..
Mosquito  1175 TAPS-----PGPPFDGSYYNMNSDRYLSYPPMQQDYSAMEMSTPP--PPVIPALPKNTGTLTRTS 1232

  Fly   883 RLAANDILATVAAASTSASLSSPPASSAASLAATATAAVEIEQDVSAVDAPAADSGSNNKRSRKS 947
            |........|..|.|.....||.|...:::|:.|.....:     :.|.||....|......|.|
Mosquito  1233 RPMVPPPDVTYHAQSVVNESSSSPQHMSSNLSNTVLGPSQ-----APVPAPKPLQGILKDPKRNS 1292

  Fly   948 LTILDKQKQQ-QEQQQLL----PPNAPQISNQP----------VAAISGNNVK-ETAATSAHG-A 995
            ......|.|| |...||:    |...|.:...|          .||::||... .|..||:.| :
Mosquito  1293 SASNSSQHQQLQHGAQLIAVQNPSPVPLVGGVPGLPLVGSTFLGAAVAGNGPNGGTGGTSSLGNS 1357

  Fly   996 VAAGVKDKAPSSKEDSTDNDN----DSDG 1020
            :..|..|  |||...|:.|.:    |:||
Mosquito  1358 LLIGTYD--PSSTNLSSFNASFGFTDADG 1384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
side-III	NP_001036681.1	V-set	59..166	CDD:462230	20/116 (17%)
		Ig_3	190..257	CDD:464046	20/73 (27%)
		Ig	289..359	CDD:472250	17/78 (22%)
		Ig strand C	308..312	CDD:409468	1/3 (33%)
		Ig strand E	335..338	CDD:409468	1/2 (50%)
		Ig strand F	348..353	CDD:409468	1/4 (25%)
		Ig_3	374..454	CDD:464046	20/80 (25%)
LOC1272555	XP_061512385.1	None