DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment stnB and gtf2a1

DIOPT Version :9

Sequence 1:	NP_001036318.2	Gene:	stnB / 4379834	FlyBaseID:	FBgn0016975	Length:	1262	Species:	Drosophila melanogaster
Sequence 2:	NP_997822.1	Gene:	gtf2a1 / 323974	ZFINID:	ZDB-GENE-030131-2694	Length:	369	Species:	Danio rerio

Alignment Length:	281	Identity:	61/281 - (21%)
Similarity:	91/281 - (32%)	Gaps:	81/281 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   304 LFEQPHVPLSQPAS-KPDLLHDDLDETIGEGEPPEQEEPDTEQSNEISSRDEPVFTSLLIRPDES 367
            |.:|..:|..||.. :..::...|  |..:|..|:|                   |.::|:|.:.
Zfish   166 LLQQQVLPQMQPGGVQAPVIQQVL--TPLQGGLPQQ-------------------TGVIIQPQQI 209

  Fly   368 THDITSQPQAATGLERQVNNMAAPSGTASTQRATTPDIEITTVEDLPRSDDEDEPEAMQEPETET 432
            .......||....:  |...||..||....|..|.|..:        :...:.:.:|.|:|....
Zfish   210 VLTGNKVPQNTQVM--QAAAMAVQSGPGDAQVQTQPQAQ--------QQQQQQQQQASQQPPMML 264

  Fly   433 KPQIEPDTEPEIVSEHSPPTERLVTQAALVDGELIAAEPEPEEMDTGLDFPLASSGQLSANPFAS 497
            :.....||..|...|.              :.|....|.|.:|.|.|.|      ||:...|..|
Zfish   265 QVDGAGDTSSEEDEEE--------------EDEYDEDEDEDKEKDGGED------GQVEEEPLNS 309

  Fly   498 PDEEEPNFAPMPAAVANIFAVNDPDSQMETPKAPSHTANIFASDPDEFDAFSAKFDSVKKDNISI 562
            .|:                 |:|.:.|     ....|.|:.....|:......|:....||.|..
Zfish   310 GDD-----------------VSDEEDQ-----ELFDTENVVVCQYDKIHRSKNKWKFHLKDGIMN 352

  Fly   563 MDG--FGGSGAITPTGGDA-W 580
            ::|  |..|.||    ||| |
Zfish   353 LNGRDFVFSKAI----GDAEW 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
stnB	NP_001036318.2	Trypan_PARP	377..496	CDD:114603	25/118 (21%)
stnB	NP_001036318.2	AP_MHD_Cterm	897..1219	CDD:299401
gtf2a1	NP_997822.1	TFIIA_alpha_beta_like	10..>60	CDD:199899
		TFIIA	13..369	CDD:281188	60/279 (22%)
		TFIIA_alpha_beta_like	<312..369	CDD:199899	18/82 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1533
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.030