Protein Alignment stnB and unc-41

DIOPT Version :9

• Sequence 1: NP_001036318.2
• Gene: stnB / 4379834
• FlyBaseID: FBgn0016975
• Length: 1262
• Species: Drosophila melanogaster
• Sequence 2: NP_001256157.1
• Gene: unc-41 / 179387
• WormBaseID: WBGene00006777
• Length: 1693
• Species: Caenorhabditis elegans
• Alignment Length: 1339
• Identity: 398/1339 - (29%)
• Similarity: 579/1339 - (43%)
• Gaps: 355/1339 - (26%)

  Fly    28 EPSSDNPFMAATVASNPFAFGADDLELGAEPEAEATH------DNDLDPAMSFF-----GTTI-- 79
            :..|..|....|||:..::     .:.|.|.:.:..|      |.:...|:|.:     .|::
 Worm   558 DEESQQPQYGETVATEAYS-----QDYGYEQQGDYHHEGVGATDENSTSAISGYEQNGASTSLGY 617

  Fly    80 ------EAEDDTLSLKSGAEEEDE---GKKPPQSQPQLQSHAHPHPPPPRPLVPPQSTQDLISTV 135
                  :..|...|...|.|.:.|   ..|...||.|:..|......||||:.|.:
 Worm   618 GDAQGYDGYDHNASYYQGQEYQQEYYQNHKYENSQYQVDQHPAESAAPPRPVAPME--------- 673

  Fly   136 SSQLDETSSELLGRIPATRSPSPVSMRDLHSPSPTPDSGLADLLDVSVDSGSSAHTQGIEADLIS 200
                     .|..:.|               |.|.|           ....||.||
 Worm   674 ---------PLFKQAP---------------PQPDP-----------FGWDSSGHT--------- 694

  Fly   201 GVAGGVRLDNPFAVPTAVPNIQAAVPLP----ATPIKQPPRPPPPRPAPPR--PAPPGQAAPQRP 259
            |.|           |||...:|...|.|    :|....|.||||.||..|:  ......|||.||
 Worm   695 GDA-----------PTASEPVQELSPTPEASSSTGTSAPARPPPARPEAPKKDETAVDAAAPPRP 748

  Fly   260 PPPLAAVNPPPAAPEADDLLDMFGTTACKPAKPPPPKSKEDILSLFEQPHVPLSQPASKPDLLHD 324
            ||                           .|:||||:                ..||:|
 Worm   749 PP---------------------------AARPPPPR----------------PAPANK------ 764

  Fly   325 DLDETIGEGEPPEQEEPDTEQSNEISSRDEPVFTSLLIRPDESTHDITSQPQAATGL--ERQVNN 387
                     |.|::.||:.:...:.....|.|.|:  ::..|||.....:..||..:  |..:.|
 Worm   765 ---------EKPKEPEPEEDAWAQFKRMTEKVSTA--VKSTESTLKNLEETSAANDIKDESYLAN 818

  Fly   388 MAAPSG--TASTQRATTPDIEITTVEDLPRSDDEDEPEAMQEPETETK------PQIEPDTE--- 441
            :....|  ..|||:            ::.|..:|.:.|.:|:.:.:.:      |.:|||.|
 Worm   819 VGGSQGFVNESTQK------------EIQRLTEEKKMEKLQKKKLKQQGKKAATPTLEPDEEDAM 871

  Fly   442 -----------------------PEIVS----EHSPPTERLVTQAALVDGELIAAEPEPEEMDTG 479
                                   ||::.    :.:|...|:.:.:|:          .|.:..:.
 Worm   872 DRAAQELAMKMASMRSDMADWKAPEMIPVKEIKKAPEIRRVDSASAI----------PPRKRSSI 926

  Fly   480 LDFPLASSGQLSANP-FASPDEEEPNFAPMPAAVANIFAVNDP--------DSQMETPKAPSHTA 535
            .|....|.|.|...| .|:|.:   :.||.|   ....|.:||        |.:...|..|...:
 Worm   927 KDVQQDSGGSLELPPHLAAPQD---SIAPNP---KGDHAPDDPILSAPAWADFETSEPMLPPSES 985

  Fly   536 NIFAS-----------DPDEFDAFSAKFDSVKKDNISIMDGFG-GSGAITPTGGDAWGGSAFGST 588
            ..|::           |..: |.|.....|.:|.:..:.|.|. ...|:.....|.:...|....
 Worm   986 GFFSNKDASNEGGVSRDATD-DPFVTTVASSEKRSSFVADPFAPQQAALIDESYDPFAVVAVEEV 1049

  Fly   589 TISANACGDTNSADDGFGNDDDDFY-AMQAPARADSVESVDKDFSVVIRPMAEETSGVAPQLAPP 652
            ...|.|..:..:|:   ..::|||| ..|:|..:                            .|.
 Worm  1050 VAMAKAKAEQAAAN---AENEDDFYNGRQSPTLS----------------------------TPT 1083

  Fly   653 PPPARGVNQAQTTSLPGLTVNPFEDVSGFPAPGLPPTDGTAIKRTDSQDTPQTPLYDEDVSQPLE 717
            |.....::|.:.        |.|||            |....:.| ..||| |||||||.||||.
 Worm  1084 PEGGSPISQQRP--------NAFED------------DFKCAELT-GLDTP-TPLYDEDDSQPLT 1126

  Fly   718 EF-PRLHYIGPGWEMQLRQPNKKK-ITGQRFWKKIVVRLVVQNDVPVVQLLNQAGDKQPFQELPL 780
            :| |:  :.|.||::.:|.|.||| ...:|.||...|||    ....:.|.|...|.||.|||.|
 Worm  1127 DFIPK--FDGDGWDLMVRHPIKKKSFMAERCWKPCYVRL----HGLTLYLYNDKKDAQPIQELLL 1185

  Fly   781 QPSYSVSEIGAQQYDQFGKIFTMKLQYIFYKERPGVRPGQVTKAERITNKLTKFAQYAIAGDYEG 845
            |.:||:|:...|.||.:|||.|:|||::.|||:.|:||||:::.  :...:||:
 Worm  1186 QATYSLSDTTLQAYDVYGKIHTVKLQFVVYKEKVGIRPGQISRL--VDGHITKY----------- 1237

  Fly   846 VKEFGSDLKKLGLPVEHAPQSSQLFKIGSMNYEDMKQFSVCIEEALFKIPALRERALTYKMEEVQ 910
                       |||:||:.|.:.|.|.||:|...::.|...:|:.|||....|.....||.:|||
 Worm  1238 -----------GLPLEHSAQCTVLLKFGSLNASHLQTFVTTVEDLLFKCKITRTAKPVYKQDEVQ 1291

  Fly   911 VTAVDEITVEQDFEGKILKQIARVRLFFLAFLTGMPTIELGVNDMWRQGKEVVGRHDIIPVATEE 975
            :...||.:...|.||.:..|.||||||.||||||.|.:|:|:||..|||||:|.|.||:|:.||.
 Worm  1292 IHCYDEYSAFVDKEGILSDQKARVRLFCLAFLTGSPVLEVGLNDRRRQGKEIVRRKDILPMYTER 1356

  Fly   976 WIRLEAVEFHSVVNQKEYERTRTIKFQPPDANYIELLRFRVRPPKNRELPLQLKATWCVSGNKVE 1040
            |||.||:||||:||:.|:::.:.|.|.|||..:.|::|||||||:|||..:.:|:...::|:|||
 Worm  1357 WIRFEALEFHSIVNKPEFDKEQVIAFSPPDGCFFEIMRFRVRPPRNREKAMTVKSIMKIAGSKVE 1421

  Fly  1041 LRADILVPGFTSRKLG-----QIPCEDVSVRFPIPECWIYLFRVEKHFRYGSVKSAHRRTGKIKG 1100
            :|.:.:......|..|     .|||||:::||||||.||||||.|:|:..||:.|...|.||:|.
 Worm  1422 IRIEAMAAAQIQRTRGSDERRNIPCEDIAIRFPIPEAWIYLFREERHWGVGSIHSKKLRPGKVKN 1486

  Fly  1101 I-ERILGAVDTLQESLIEVTSGQAKYEHHHRAIVWRCPRLPKEGQGAYTTHQLVCRMALTSYDQI 1164
            : :|:||||...:.:|||...|:|||||.:|::|||.||||::...||.:|.|.||..|:|:|.:
 Worm  1487 LKDRLLGAVQASEPNLIECAIGEAKYEHVYRSLVWRIPRLPEKHHAAYKSHLLKCRFELSSFDLM 1551

  Fly  1165 PSELAPYAFVEFTMPATQVSHTTVRSVSVQDSDGDEPPEKYVRYLARHEYKVGIETTH------- 1222
            |.|..|...|:||||...||:|.||||||:..:..:..||:|||:|:::|||.|:...
 Worm  1552 PEEFLPRCDVDFTMPLATVSNTVVRSVSVEQHEDSDRVEKFVRYVAKYQYKVEIDYVQCADLDLD 1616

  Fly  1223 --GESTNAYLAATRPIREEPPTTATKPTASPVAPSDSDT 1259
              ..|.|.. ||..|:.|     ..:||.:| :..:|||
 Worm  1617 MADPSVNPE-AAAAPVPE-----LHQPTFNP-STQESDT 1648

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
stnB	NP_001036318.2	Trypan_PARP	377..496	CDD:114603	28/159 (18%)
		AP_MHD_Cterm	897..1219	CDD:299401	160/327 (49%)
unc-41	NP_001256157.1	PH-like	1145..>1193	CDD:302622	21/51 (41%)
		AP_MHD_Cterm	1279..1606	CDD:299401	160/326 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162563
Domainoid	1	1.000	327	1.000	Domainoid score	I633
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	476	1.000	Inparanoid score	I816
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006875
OrthoInspector	1	1.000	-	-		oto17798
orthoMCL	1	0.900	-	-		OOG6_108692
Panther	1	1.100	-	-	LDO	PTHR10529
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1533
SonicParanoid	1	1.000	-	-		X2217
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.920