Protein Alignment RunxA and runx1

DIOPT Version :9

• Sequence 1: NP_001259747.1
• Gene: RunxA / 4379817
• FlyBaseID: FBgn0083981
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: NP_571678.1
• Gene: runx1 / 58126
• ZFINID: ZDB-GENE-000605-1
• Length: 451
• Species: Danio rerio
• Alignment Length: 463
• Identity: 176/463 - (38%)
• Similarity: 224/463 - (48%)
• Gaps: 115/463 - (24%)

  Fly    83 LAERTLGDFLTEHPGELIRTSSPLFVCTVLPPHWRSNKTLPVAFKVVSLGDIMDGTMVTVRAGND 147
            :|:|::.:.|::|||||:||.||.|:|:|||.|||.|||||:|||||:||||.|||:|||.||||
Zfish    51 MADRSMVEVLSDHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDIPDGTLVTVMAGND 115

  Fly   148 ENYCAELRNCTAVMKNQVAKFNDLRFVGRSGRGKSFTLTITVSTNPPHIATYNKAIKVTVDGPRE 212
            |||.|||||.||.:|||||:||||||||||||||||||||||.||||.:|||.:|||:|||||||
Zfish   116 ENYSAELRNATAAIKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYQRAIKITVDGPRE 180

  Fly   213 PRSKTML--------SLLGQQQQFHFAFGQRPFHF---STDPLSGFRMPPIG---------NCQS 257
            ||.....        :|...:|....|....|.|.   :|.|.  ...||.|         :.|.
Zfish   181 PRRHRQKPDEAVKPGALAFSEQLRRSAMRCSPHHGPAPNTRPT--LNTPPFGSPAHSQIPDSRQM 243

  Fly   258 ASNTHWGYGSAASAYSPYLA--SSGLSSCTTPTSAQFNNPALGFTCSSNDQSNNQDFGGATNRDC 320
            .::..|.|   ..:| |||.  |:.....|||.|.  |..||  .|.......:...|...:...
Zfish   244 QTSPSWSY---EQSY-PYLGPISTPAVHPTTPISP--NRTAL--HCPELTAFTDPRVGLERSFPS 300

  Fly   321 VPMLPDSTASDLDQHLSSLVGSTSGQMTHHSLLGAGGQTSISSTVNGASG-GGSAGAGTAGGGAG 384
            :|.|||...||      ..|...:|..|:           ..:.|..|.| |.||.:..||
Zfish   301 LPSLPDGRFSD------PRVPYPTGAFTY-----------TPTPVTSAIGIGMSAMSSPAG---- 344

  Fly   385 SGGGAGGGAGGNSILVPRYHTNASNEYNVHSSQ---------NGPRSLSDSSQAESPVQEDLLTT 440
                             ||||.....|...|||         :.|..|..||.|.| .|..::.:
Zfish   345 -----------------RYHTYLPPAYPAGSSQAQAGAFQASSSPYHLYYSSAAGS-YQFSMMPS 391

  Fly   441 NTPNLGSTAGGGAANGGAG-------SNAGSGAAGSGAGGAGGASSAVGNPAMLGANQNFPGIVN 498
                      ||||.|...       :||.:|             ||:.:|::  .||: .|:|.
Zfish   392 ----------GGAAAGERSPPRILPCTNASTG-------------SALLHPSL--PNQS-EGVVE 430

  Fly   499 -QAQHSAA 505
             :..||::
Zfish   431 AEGSHSSS 438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RunxA	NP_001259747.1	Runt	95..216	CDD:279225	97/120 (81%)
runx1	NP_571678.1	Runt	63..184	CDD:307137	97/120 (81%)
		Atrophin-1	<160..426	CDD:331285	90/340 (26%)
		RunxI	359..451	CDD:312115	26/107 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	211	1.000	Domainoid score	I2735
eggNOG	1	0.900	-	-		E1_KOG3982
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	1	1.000	-	-		mtm6398
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11950
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X738
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	6.000