Protein Alignment RunxA and runx2b

DIOPT Version :9

• Sequence 1: NP_001259747.1
• Gene: RunxA / 4379817
• FlyBaseID: FBgn0083981
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: NP_998027.2
• Gene: runx2b / 405788
• ZFINID: ZDB-GENE-040629-4
• Length: 464
• Species: Danio rerio
• Alignment Length: 394
• Identity: 150/394 - (38%)
• Similarity: 194/394 - (49%)
• Gaps: 91/394 - (23%)

  Fly    86 RTLGDFLTEHPGELIRTSSPLFVCTVLPPHWRSNKTLPVAFKVVSLGDIMDGTMVTVRAGNDENY 150
            |::.:.:.:||.||:||.||.|:|:|||.|||.|||||||||||:||::.|||:|||.|||||||
Zfish    62 RSMAEIIADHPAELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGEVPDGTVVTVMAGNDENY 126

  Fly   151 CAELRNCTAVMKNQVAKFNDLRFVGRSGRGKSFTLTITVSTNPPHIATYNKAIKVTVDGPREPRS 215
            .|||||.:.|||||||:||||||||||||||||||||||.||||.:|||::|||||||||||||.
Zfish   127 SAELRNASGVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPPQVATYHRAIKVTVDGPREPRR 191

  Fly   216 --------------KTMLSLLGQQQQFHFAF---GQRPFHFSTDPLSGFRMPPIGNC------QS 257
                          ...||.|.:.:|.....   .|.|....:.|.|   ..|.|..      |:
Zfish   192 HRPKLDDSPKAGLFSDRLSELERIRQTTMRVTVPTQTPRPSLSSPNS---YTPQGQTQITDPRQA 253

  Fly   258 ASNTHWGYGSAASAYSPYLASSGLSSCTTP----------------------------------- 287
            .|:..|.|.....:|...:||..:.| |||
Zfish   254 QSSPPWSYDQTYPSYLSPMASPSVHS-TTPLSSSRATGLPSISDVPRRLPGSTDLSPFPGQFERQ 317

  Fly   288 -------TSAQFNNPAL----GFTCSSNDQSNNQDFGGATNRDCV-PMLPDSTASDLDQHLSS-- 338
                   |.::|::|.:    .||.:....:.....|.|.....: |..|.||.|......||
Zfish   318 FPAFSSLTESRFSSPRMHYPATFTYTPTPVTTGMSLGSAHYHTYLPPPYPGSTQSQSGPFQSSST 382

  Fly   339 ---LVGSTSGQMTHHSLLGAGGQTSISSTVNGASGGGSAGAGTA-------GGGAGSGGGAGGGA 393
               ..|::||  ::...:..||:.|.:..:...:   ||..||:       ....||||..|.|:
Zfish   383 PYLYYGASSG--SYQFSMVPGGERSPTRMMPPCT---SASTGTSLVNPNLPVQADGSGGVEGDGS 442

  Fly   394 GGNS 397
            ..||
Zfish   443 HSNS 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RunxA	NP_001259747.1	Runt	95..216	CDD:279225	96/134 (72%)
runx2b	NP_998027.2	Runt	71..192	CDD:279225	96/120 (80%)
		RunxI	370..464	CDD:285676	22/82 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	211	1.000	Domainoid score	I2735
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	1	1.000	-	-		mtm6398
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11950
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X738
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.100