Protein Alignment RunxA and lz

DIOPT Version :9

• Sequence 1: NP_001259747.1
• Gene: RunxA / 4379817
• FlyBaseID: FBgn0083981
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: NP_511099.2
• Gene: lz / 31883
• FlyBaseID: FBgn0002576
• Length: 826
• Species: Drosophila melanogaster
• Alignment Length: 748
• Identity: 223/748 - (29%)
• Similarity: 300/748 - (40%)
• Gaps: 237/748 - (31%)

  Fly     5 TTSSNSTASNANNNNNNTANNNNTSSNNNTTNTNGSSNNNTSGNNNNSSGNNSNTEQNTPPTPAQ 69
            :..|:|....|:|...::.::.:|..::::|    :||||.:|.:|::|.||:...|
  Fly   215 SVGSSSPTGGASNGTAHSGHSGHTGGHSSST----ASNNNNNGASNSNSNNNNAVHQ-------- 267

  Fly    70 LLNEAYTKMTSDIL-AERTLGDFLTEHPGELIRTSSPLFVCTVLPPHWRSNKTLPVAFKVVSLGD 133
                       |:| .||.:.....||||||:|||:|.|:|:.||.|||||||||:|||||:|.:
  Fly   268 -----------DLLWMERLVQKRQQEHPGELVRTSNPYFLCSALPAHWRSNKTLPMAFKVVALAE 321

  Fly   134 IMDGTMVTVRAGNDENYCAELRNCTAVMKNQVAKFNDLRFVGRSGRGKSFTLTITVSTNPPHIAT 198
            :.|||.||:|||||||.||||||.|..|||.|||||||||||||||||||||||||:|:||.:||
  Fly   322 VGDGTYVTIRAGNDENCCAELRNFTTQMKNDVAKFNDLRFVGRSGRGKSFTLTITVATSPPQVAT 386

  Fly   199 YNKAIKVTVDGPREPRSKTMLSLLGQQQQFHFAFGQRPFHFSTDPLSGF-------------RMP 250
            |.|||||||||||||||||  |..|.........||||:      :.||             |..
  Fly   387 YAKAIKVTVDGPREPRSKT--SPTGGPHYRALGLGQRPY------IDGFPSTKALHELESLRRSA 443

  Fly   251 PIGNCQSASNTHWGYGSAASAYSPYLASSGLSSCTTPTSAQFNNPALGFT----------CSSND 305
            .:....:|:.......|||:|    :|::..:...|||.......|.|..          .|||.
  Fly   444 KVAAVTTAAAAAATAASAANA----VAAAAAAVAVTPTGGGGGVAAGGVAGGAGAGLVQQLSSNY 504

  Fly   306 QSNNQDFGGATNRDCVPMLPDSTASDLDQHLSSLVGSTSGQMT--------------------HH 350
            .|.|    ...|.||....|::      .|:.:.....:|:.|                    ||
  Fly   505 SSPN----STINSDCQVYKPNA------PHIQAAEMMGAGEWTNGSSSSAAAYYHSHAHHPHAHH 559

  Fly   351 S----------------------LLGAGGQTSISSTVNGASGGGSAGAGTAGGGAGSGGGAGGGA 393
            :                      .:|.||        |||:.|...|.|.   |.|.....||..
  Fly   560 AHAHLQHQMALPPPPPPPAAAPVSVGVGG--------NGATMGMGMGVGV---GMGMNHYGGGYD 613

  Fly   394 GGNSILVPRYHTNASNEYNVHSSQNGPRSLSDSSQAESPVQEDLLTTNTPNLGSTAGGGAANGGA 458
            ..||:        .:.:|..|.....| .:.....|..|.|             |||.|..|.|.
  Fly   614 SANSL--------EAGQYAAHLPAVLP-EMHGHGFATDPYQ-------------TAGYGGGNTGG 656

  Fly   459 GSNAGSGAAGSGAGGAGGASSAVGNPAMLGANQNFPGIVNQAQHSAASAYGGGTGVVGGGHGSAA 523
            ||.:.|                         ..::.|..|||..:....|..|:.:....:|..|
  Fly   657 GSASKS-------------------------ELDYGGSYNQAWSNGYQNYQYGSCLATAQYGPQA 696

  Fly   524 AAAAGCNGSLYPVLPASLLYSQLYTAANQSAHGFHSHTLPAHASPNSSVHGELQSVMDHISNVGV 588
            |..     ...|..|..:|..|||:..||:....|.|:           ..:|:..:
  Fly   697 APP-----PQPPPPPPVVLCPQLYSTVNQNQIHLHLHS-----------SEKLEQYL-------- 737

  Fly   589 RQQHNIMAGGGVTHPGDLTLIGNCGASVRNIEDG---------NSNRQVAALAAHRGHHNPTDN- 643
                     |..|....||:....|:|..:||.|         ::.:|.......:..|:|...
  Fly   738 ---------GTATSADHLTIGSLTGSSRSSIEIGQDQYHQQVHHAQQQQQQQQQQQQVHHPQQQQ 793

  Fly   644 -------GGS------------------VWRPY 651
                   |||                  |||||
  Fly   794 VESAGEVGGSGAGGVESAREEDVGDLSQVWRPY 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RunxA	NP_001259747.1	Runt	95..216	CDD:279225	95/120 (79%)
lz	NP_511099.2	Runt	283..404	CDD:279225	95/120 (79%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	132	1.000	Domainoid score	I3175
eggNOG	1	0.900	-	-		E1_KOG3982
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D109070at6656
OrthoFinder	1	1.000	-	-		FOG0000993
OrthoInspector	1	1.000	-	-		otm14562
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11950
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X738
	8	7.920