Protein Alignment RunxA and Runx3

DIOPT Version :10

• Sequence 1: NP_001259747.1
• Gene: RunxA / 4379817
• FlyBaseID: FBgn0083981
• Length: 663
• Species: Drosophila melanogaster
• Sequence 2: NP_001398707.1
• Gene: Runx3 / 156726
• RGDID: 620082
• Length: 423
• Species: Rattus norvegicus
• Alignment Length: 394
• Identity: 153/394 - (38%)
• Similarity: 190/394 - (48%)
• Gaps: 88/394 - (22%)

  Fly    86 RTLGDFLTEHPGELIRTSSPLFVCTVLPPHWRSNKTLPVAFKVVSLGDIMDGTMVTVRAGNDENY 150
            |::.|.|.:|.|||:||.||.|:|:|||.|||.|||||||||||:|||:.|||:|||.|||||||
  Rat    68 RSMVDVLADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENY 132

  Fly   151 CAELRNCTAVMKNQVAKFNDLRFVGRSGRGKSFTLTITVSTNPPHIATYNKAIKVTVDGPREPRS 215
            .|||||.:||||||||:||||||||||||||||||||||.|||..:|||::|||||||||||||
  Rat   133 SAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREPR- 196

  Fly   216 KTMLSLLGQQQQFHFAFG---------------------------QRPFHFSTDPLSGFRMP--- 250
            :....:..|.:.|...||                           |.|...|:| |:.|..|
  Rat   197 RHRQKIEDQTKAFPDRFGDLRMRVTPSTPSPRGSLSTTSHFSSQAQTPIQGSSD-LNPFSDPRQF 260

  Fly   251 --PIGNCQSASNTHW-----GYGSAASAYSPYLAS------SGLSSCTTPTSAQFNNPALGFTCS 302
              .....||.:.:.:     .|..|.||..||.|:      .|||....|.|::|::..|.....
  Rat   261 DRSFPTLQSLTESRFPDPRMHYPGAMSAAFPYSATPSGTSLGGLSVAGMPASSRFHHTYLPPPYP 325

  Fly   303 SNDQSNNQDFGGATNRDCVPMLPDSTASDLDQHLSSLVGSTSGQMTHHSLLGAGGQTSISSTVNG 367
            ...||.:..|               .|:....||  ..|::||..........||:.|.:..:..
  Rat   326 GAPQSQSGPF---------------QANPAPYHL--FYGTSSGSYQFSMAAAGGGERSPTRMLTS 373

  Fly   368 ASGGGSAGAGTAGG---GAGSGGGAGGGAGGNSILVPRYHTNASNEYNVHSSQNGPRSLSDSSQA 429
            ...|.|..||....   |...|..|.|                       |..|.|.:||...:.
  Rat   374 CPTGASVSAGNLMNPSLGQADGVEADG-----------------------SHSNSPTALSTPGRM 415

  Fly   430 ESPV 433
            :..|
  Rat   416 DEAV 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RunxA	NP_001259747.1	Runt	88..216	CDD:459963	99/127 (78%)
Runx3	NP_001398707.1	Runt	70..198	CDD:459963	99/128 (77%)
		RunxI	328..423	CDD:430037	26/132 (20%)