DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ND-49 and Ndufs2

DIOPT Version :9

Sequence 1:	NP_001259064.1	Gene:	ND-49 / 43798	FlyBaseID:	FBgn0039909	Length:	468	Species:	Drosophila melanogaster
Sequence 2:	NP_001011907.1	Gene:	Ndufs2 / 289218	RGDID:	1307109	Length:	463	Species:	Rattus norvegicus

Alignment Length:	448	Identity:	349/448 - (77%)
Similarity:	388/448 - (86%)	Gaps:	0/448 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 QLVAAGSAALTSQETRRGAAKWYPDPEFMKQFSGPVMYPDEVTSLWTVPPWNSKVTPVEKSVRNL 85
            |::.|||......:..|||.:|.||.|:.:||||.||||.:.|:.|..||||......||.|.|:
  Rat    16 QVLRAGSGIRLPSQPSRGARRWQPDIEWAEQFSGAVMYPSKETAHWKPPPWNDVDVLKEKVVTNV 80

  Fly    86 TLNFGPQHPAAHGVLRLVLELDGETVMRADPHIGLLHRGTEKLIEYKTYTQALPYFDRLDYVSMM 150
            |||||||||||||||||||||.||.|.:.||||||||||||||||||||.|||||||||||||||
  Rat    81 TLNFGPQHPAAHGVLRLVLELSGEMVRKCDPHIGLLHRGTEKLIEYKTYLQALPYFDRLDYVSMM 145

  Fly   151 CNEQCYSLAVEKLLNIDVPLRAKYIRTLFAEITRILNHIMAVGTHALDVGALTPFFWLFEEREKM 215
            ||||.|||||||||||..|.||::||.||.||||||||||||.|||||:||:|||||:|||||||
  Rat   146 CNEQAYSLAVEKLLNIQPPPRAQWIRVLFGEITRILNHIMAVTTHALDIGAMTPFFWMFEEREKM 210

  Fly   216 MEFYERVSGARMHAAYIRPGGVSLDMPLGLMDDIYEFASKFAERLDEVEDVLTTNRIWVQRTEDI 280
            .|||||||||||||||||||||..|:|||||||||||:..|:.|:||||::||.||||..||.||
  Rat   211 FEFYERVSGARMHAAYIRPGGVHQDLPLGLMDDIYEFSKNFSLRIDEVEEMLTNNRIWRNRTVDI 275

  Fly   281 GIVTAEEALNYGFSGVMLRGSGIKWDLRKQQPYDAYNLVNFDVPIGTKGDCYDRYLCRVEEMRQS 345
            |:|:||:||||||||||||||||:|||||.||||.|:.|.||||||::|||||||||||||||||
  Rat   276 GVVSAEDALNYGFSGVMLRGSGIQWDLRKTQPYDVYDQVEFDVPIGSRGDCYDRYLCRVEEMRQS 340

  Fly   346 LRIIDQCLNQMPAGEIKTDDAKVAPPSRSEMKTSMEALIHHFKLFTQGYQVPPGATYTAIEAPKG 410
            ||||:||||:||.||||.|||||:||.|:|||||||:|||||||:|:||||||||||||||||||
  Rat   341 LRIIEQCLNKMPPGEIKVDDAKVSPPKRAEMKTSMESLIHHFKLYTEGYQVPPGATYTAIEAPKG 405

  Fly   411 EFGVYLISDGSSRPYRCKIKAPGFAHLAALEKIGKQHMLADVVAIIGTLDVVFGEIDR 468
            ||||||:|||||||||||||||||||||.|:|:.|.||||||||||||.|:|||||||
  Rat   406 EFGVYLVSDGSSRPYRCKIKAPGFAHLAGLDKMSKGHMLADVVAIIGTQDIVFGEIDR 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ND-49	NP_001259064.1	PRK06075	79..468	CDD:180385	322/388 (83%)
ND-49	NP_001259064.1	NuoD	79..468	CDD:223722	322/388 (83%)
Ndufs2	NP_001011907.1	PRK06075	77..463	CDD:180385	320/385 (83%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166341907
Domainoid	1	1.000	477	1.000	Domainoid score	I403
eggNOG	1	0.900	-	-		E1_COG0649
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H56659
Inparanoid	1	1.050	727	1.000	Inparanoid score	I590
OMA	1	1.010	-	-		QHG60638
OrthoDB	1	1.010	-	-		D212488at33208
OrthoFinder	1	1.000	-	-		FOG0003234
OrthoInspector	1	1.000	-	-		oto97675
orthoMCL	1	0.900	-	-		OOG6_101051
Panther	1	1.100	-	-	LDO	PTHR11993
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2189
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	15	14.810