Protein Alignment Tdg and tdg

DIOPT Version :10

• Sequence 1: NP_651925.1
• Gene: Tdg / 43796
• FlyBaseID: FBgn0026869
• Length: 1738
• Species: Drosophila melanogaster
• Sequence 2: NP_001004982.1
• Gene: tdg / 448432
• XenbaseID: XB-GENE-1006128
• Length: 441
• Species: Xenopus tropicalis
• Alignment Length: 505
• Identity: 175/505 - (34%)
• Similarity: 235/505 - (46%)
• Gaps: 127/505 - (25%)

  Fly   538 PENQDDGYETSAGDVLTPNSHSSSTHSIT--PQHQMQHSNIVLMTQNQKKSDDLQLTKVTLSGEA 600
            |.|.|.|.|            ..:.|.:|  |.|::|                      ..||.|
 Frog    30 PSNMDLGNE------------QQTLHPLTGVPAHELQ----------------------AFSGMA 60

  Fly   601 HTDPNACSSNSSQGQVLASQSHLELSEGTRCSSHASVVDPYSFMGEELHMHSPSHRHLDAVTTGP 665
            ..:|          |||.:.:.::..|..........:.|.....|.              |||.
 Frog    61 ANEP----------QVLHTLTGVQAQEPINGEMQVPEMIPNLAEAEP--------------TTGK 101

  Fly   666 GRYGILVSNDTPECLSREMYRHSQQSTTVLEQTDSSSCGINFKPMPKKRGRKKKLVAVNADTSQM 730
            .:.|...|...|:                 :|...|:      ..||..|:::|:    .||.
 Frog   102 RKRGKAPSEPKPK-----------------KQAAKSA------KAPKSSGKQEKI----TDTF-- 137

  Fly   731 TTPVDQQKVSAGRADCEDGGGDQAAKPKERKKHDRFNGMSEEEVIKRTIPDHLCDNLDIVIVGIN 795
                                       |.::|.|||||:||.|::.:|:||.|..||||||:|||
 Frog   138 ---------------------------KVKRKVDRFNGVSEAELMTKTLPDILTFNLDIVIIGIN 175

  Fly   796 PGLFAAYKGHHYAGPGNHFWKCLYLAGLTQEQMSADEDHKL-IKQGIGFTNMVARATKGSADLTR 859
            |||.||||||||.||||||||||:|:||:..|::..:||.| .|.||||||||.|.|.||.||:.
 Frog   176 PGLMAAYKGHHYPGPGNHFWKCLFLSGLSDMQLNHLDDHSLPEKYGIGFTNMVERTTPGSKDLSS 240

  Fly   860 KEIKEGSRILLEKLQRFRPKVAVFNGKLIFEVFSGK------KEFHFGRQPDRVDGTDTFIWVMP 918
            ||.:||.||||||||:::|:||.||||.|:|:||.:      |:|.||.||.||..|||..:|||
 Frog   241 KEFREGGRILLEKLQKYKPRVAAFNGKCIYEIFSKEIFGVKIKKFEFGIQPHRVPETDTVCYVMP 305

  Fly   919 SSSARCAQLPRAADKVPFYAALKKFRDFLNGQIPHIDESECVFT-DQRIRLCSAQQQVDIVGKIN 982
            ||||||||.|||.|||..|..||:.|:.|.|.....:..|..:: |.::....|::|.....|.:
 Frog   306 SSSARCAQFPRAQDKVHHYIKLKELRNQLKGVESSREVQEVQYSFDLQLAQADAKRQAIKEEKYD 370

  Fly   983 KTHQPPLGDHPSSLTVVSNCSG--PIAGDAECGIVAEESDQVQSEKMIPQ 1030
            ..:....|:..:..| .|..||  ..:.||......|.:.|.|:.:.|||
 Frog   371 PGYNEATGEQFNEQT-TSGESGMCNFSTDATVSSNPEFNGQGQNGQWIPQ 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdg	NP_651925.1	UDG-like	714..962	CDD:444933	128/254 (50%)
		motif A	793..797	CDD:381679	3/3 (100%)
tdg	NP_001004982.1	UDG-like	2..364	CDD:444933	161/447 (36%)
		motif A	173..177	CDD:381679	3/3 (100%)