Protein Alignment Tdg and thp1

DIOPT Version :10

• Sequence 1: NP_651925.1
• Gene: Tdg / 43796
• FlyBaseID: FBgn0026869
• Length: 1738
• Species: Drosophila melanogaster
• Sequence 2: NP_588515.1
• Gene: thp1 / 2539432
• PomBaseID: SPCC965.05C
• Length: 325
• Species: Schizosaccharomyces pombe
• Alignment Length: 302
• Identity: 88/302 - (29%)
• Similarity: 148/302 - (49%)
• Gaps: 54/302 - (17%)

  Fly   642 SFMGEELHMHSPSHRHLDAVTTGPGRYGILVSNDT---PECLSREMYRHS-----QQSTTVLEQT 698
            ||..|.|.:......     |:|    |||....|   .|.|.|..:.|:     .:.|.|::.:
pombe    31 SFDDENLELEESREE-----TSG----GILKKAKTQSFSESLERFRFAHAGSNNEYRKTDVVKNS 86

  Fly   699 DSSSCGINFKPMPKKRGRKKKLVAVNADTSQMTTPVDQQKVSAGRADCEDGGGDQAAKPKERKKH 763
            |:.: |:          .|..:..:..:.......|:..|.|..:|..:        |...:||:
pombe    87 DTDN-GL----------LKSAVETITLENGLRNRRVNVTKKSTLKASVK--------KSTLKKKN 132

  Fly   764 DRFNGMSEEEVIKRTIPDHLCDNLDIVIVGINPGLFAAYKGHHYAGPGNHFWKCLYLAGLTQ--E 826
            :      .:..:.:.:||::|:|...:|||:|||:.::.|||.:|.|.|.|||.|..:.|.:  .
pombe   133 E------VDPALLQGVPDYICENPYAIIVGLNPGITSSLKGHAFASPSNRFWKMLNKSKLLEGNA 191

  Fly   827 QMSADEDHKLIKQGIGFTNMVARATKGSADLTRKEIKEGSRILLEKLQRFRPKVAVF-NGKLIFE 890
            :.:...|..|...|:|.||:.||.:...|||.::|:::|:|||.||::|:||:|.:| :||.|:|
pombe   192 EFTYLNDKDLPAHGLGITNLCARPSSSGADLRKEEMQDGARILYEKVKRYRPQVGLFISGKGIWE 256

  Fly   891 ----VFSGK---KEFHFGRQPDRVDGTDTFIWVMPSSSARCA 925
                :.:||   |.|.||.||::....:.|:.:  |||.|.|
pombe   257 EMYKMLTGKKLPKTFVFGWQPEKFGDANVFVGI--SSSGRAA 296

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tdg	NP_651925.1	UDG-like	714..962	CDD:444933	70/222 (32%)
		motif A	793..797	CDD:381679	2/3 (67%)
thp1	NP_588515.1	UDG-like	5..325	CDD:444933	88/302 (29%)
		motif A	156..160	CDD:381679	2/3 (67%)