DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Thd1 and thp1

DIOPT Version :9

Sequence 1:	NP_001259060.1	Gene:	Thd1 / 43796	FlyBaseID:	FBgn0026869	Length:	1738	Species:	Drosophila melanogaster
Sequence 2:	NP_588515.1	Gene:	thp1 / 2539432	PomBaseID:	SPCC965.05c	Length:	325	Species:	Schizosaccharomyces pombe

Alignment Length:	302	Identity:	88/302 - (29%)
Similarity:	148/302 - (49%)	Gaps:	54/302 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   642 SFMGEELHMHSPSHRHLDAVTTGPGRYGILVSNDT---PECLSREMYRHS-----QQSTTVLEQT 698
            ||..|.|.:......     |:|    |||....|   .|.|.|..:.|:     .:.|.|::.:
pombe    31 SFDDENLELEESREE-----TSG----GILKKAKTQSFSESLERFRFAHAGSNNEYRKTDVVKNS 86

  Fly   699 DSSSCGINFKPMPKKRGRKKKLVAVNADTSQMTTPVDQQKVSAGRADCEDGGGDQAAKPKERKKH 763
            |:.: |:          .|..:..:..:.......|:..|.|..:|..:        |...:||:
pombe    87 DTDN-GL----------LKSAVETITLENGLRNRRVNVTKKSTLKASVK--------KSTLKKKN 132

  Fly   764 DRFNGMSEEEVIKRTIPDHLCDNLDIVIVGINPGLFAAYKGHHYAGPGNHFWKCLYLAGLTQ--E 826
            :      .:..:.:.:||::|:|...:|||:|||:.::.|||.:|.|.|.|||.|..:.|.:  .
pombe   133 E------VDPALLQGVPDYICENPYAIIVGLNPGITSSLKGHAFASPSNRFWKMLNKSKLLEGNA 191

  Fly   827 QMSADEDHKLIKQGIGFTNMVARATKGSADLTRKEIKEGSRILLEKLQRFRPKVAVF-NGKLIFE 890
            :.:...|..|...|:|.||:.||.:...|||.::|:::|:|||.||::|:||:|.:| :||.|:|
pombe   192 EFTYLNDKDLPAHGLGITNLCARPSSSGADLRKEEMQDGARILYEKVKRYRPQVGLFISGKGIWE 256

  Fly   891 ----VFSGK---KEFHFGRQPDRVDGTDTFIWVMPSSSARCA 925
                :.:||   |.|.||.||::....:.|:.:  |||.|.|
pombe   257 EMYKMLTGKKLPKTFVFGWQPEKFGDANVFVGI--SSSGRAA 296

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Thd1	NP_001259060.1	UDG_like	714..962	CDD:294330	70/222 (32%)
thp1	NP_588515.1	UDG_like	5..325	CDD:294330	88/302 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	107	1.000	Domainoid score	I1658
eggNOG	1	0.900	-	-		E1_COG3663
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006159
OrthoInspector	1	1.000	-	-		oto101021
orthoMCL	1	0.900	-	-		OOG6_104831
Panther	1	1.100	-	-	LDO	PTHR12159
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1493
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.840