DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment zfh2 and ZFHX3

DIOPT Version :9

Sequence 1:	NP_524623.2	Gene:	zfh2 / 43795	FlyBaseID:	FBgn0004607	Length:	3005	Species:	Drosophila melanogaster
Sequence 2:	NP_001373664.1	Gene:	ZFHX3 / 463	HGNCID:	777	Length:	3703	Species:	Homo sapiens

Alignment Length:	3734	Identity:	857/3734 - (22%)
Similarity:	1230/3734 - (32%)	Gaps:	1551/3734 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly     5 DVETFNGKIVYNLDGSAHII--ATDNTNGG---GSGSGQNCYGST-TNSLKNLSKDKGRGQEEKD 63
            |||...|:|||..||||:|:  .:..|.||   |||||.....|. .|||      .|.|.::.|
Human   125 DVENLAGEIVYQPDGSAYIVESLSQLTQGGGACGSGSGSGPLPSLFLNSL------PGAGGKQGD 183

  Fly    64 IEHPS-----------QYHREQSDNKRQEEAVDNRPGVESLGSACYKSSPKIHSFRVVSAQ---- 113
               ||           .:|...|..|..|......|...:|...    ||.:|||||...:
Human   184 ---PSCAAPVYPQIINTFHIASSFGKWFEGPDQAFPNTSALAGL----SPVLHSFRVFDVRHKSN 241

  Fly   114 --------DANSTCQ-------------DQIRAFKIQKPILMCFICKLSFGNVKSFSLHANTEHR 157
                    .|.|:|.             |....:..:|||||||:||||||.|:||..||..:||
Human   242 KDYLNSDGSAKSSCVSKDVPNNVDLSKFDGFVLYGKRKPILMCFLCKLSFGYVRSFVTHAVHDHR 306

  Fly   158 LNLEELDQQLLNREYSSAIIQR-NMDEKPQISFLQPLANNDASADTNDTEKL------------Q 209
            :.|.|.::::|:.:..|||||. ..|::|.:|||:| .|.:.......|..|            .
Human   307 MTLSEDERKILSNKNISAIIQGIGKDKEPLVSFLEP-KNKNFQHPLVSTANLIGPGHSFYGKFSG 370

  Fly   210 TATEGSDATLPSSPQPVFRNVSELEPENKQE--TEQNRLLNQDREQEPESDQHTSSSKMAAPSAY 272
            ...||.:| ||:.        |...||..|.  ...:.|||..         ..:||.:..|...
Human   371 IRMEGEEA-LPAG--------SAAGPEQPQAGLLTPSTLLNLG---------GLTSSVLKTPITS 417

  Fly   273 IPLSSPKVAGKLTVKFGSLNSATAKTNNLSKVSSTSSPPSTYASGEVLS----PSTDNISNHKST 333
            :||             |.|.|:..|::......:..........|:..|    |:.:.....:..
Human   418 VPL-------------GPLASSPTKSSEGKDSGAAEGEKQEVGDGDCFSEKVEPAEEEAEEEEEE 469

  Fly   334 HCNQETEPPSSSSSEVEMKIGSMSTSPQTNDSDVPCSGFLQMQHMTTGGAY-------------- 384
            ...:|.|.......|.|...|.....|...|.::.     ...|...|.|.
Human   470 EEAEEEEEEEEEEEEEEEDEGCKGLFPSELDEELE-----DRPHEEPGAAAGSSSKKDLALSNQS 529

  Fly   385 -----------------TPQVSSFHASLAALAANESNDNRVKLITEFLQQQLQQHQSSLFPSPCP 432
                             |...||..||...:....:..||:...:|
Human   530 ISNSPLMPNVLQTLSRGTASTSSNSASSFVVFDGANRRNRLSFNSE------------------- 575

  Fly   433 DHPDLNGVDCKTCE---LLDIQQRSKS--------PSSS----------HHQFSQSLPQLQIQSQ 476
                  ||.....|   .||....|.:        |:.|          |||.:.||.:|.:
Human   576 ------GVRANVAEGGRRLDFADESANKDNATAPEPNESTEGDDGGFVPHHQHAGSLCELGV--- 631

  Fly   477 PQQTPHRSPCSNSVALPVSPSASSVASVGNASTATSSFTIGACSEHINGRPQGVDCARCEMLLNS 541
                   ..|         ||.|                             ||:|.:|:.:|.|
Human   632 -------GEC---------PSGS-----------------------------GVECPKCDTVLGS 651

  Fly   542 ARLNSG--VQMSTRNSCKTLKCPQCNWHYKYQETLEIHMREKHPDGESACGYCLAGQQHPRLARG 604
            :|...|  ..|.:||||||||||:||||||||:|||.||:||||:...:|.||.:||.|||||||
Human   652 SRSLGGHMTMMHSRNSCKTLKCPKCNWHYKYQQTLEAHMKEKHPEPGGSCVYCKSGQPHPRLARG 716

  Fly   605 ESYSCGYKPYRCEICNYSTTTKGNLSIHMQSDKHLNNMQEL-NSSQNMV----AAAAAAAVTGKL 664
            |||:|||||:|||:|||||||||||||||||||||||||.| |.....|    |.||||||
Human   717 ESYTCGYKPFRCEVCNYSTTTKGNLSIHMQSDKHLNNMQNLQNGGGEQVFSHTAGAAAAAV---- 777

  Fly   665 LLSSSSPQVTAACPSNSGSGAGSGSSNIVGGTASLSGNATPSVTGANSSNANAGSNTNNAGTKP- 728
                    ..||..:|..|..|:.|.                                   |||
Human   778 --------AAAAAAANISSSCGAPSP-----------------------------------TKPK 799

  Fly   729 -KPSFRCDICSYDTSVARNLRIHMTSEKHTHNMAVLQNNIKHIQAFNFLQQQQQSGTGNIASHSS 792
             ||::||::|.|:|:||||||||||||||.|||.:||.|:..|      |..:..|.|:
Human   800 TKPTWRCEVCDYETNVARNLRIHMTSEKHMHNMMLLQQNMTQI------QHNRHLGLGS------ 852

  Fly   793 GSFMPEVALADLAYNQALMIQLLHQQQQHQQSANTKLSPSSSPVSTPDQFSFSPKPIKLNHG--- 854
               :|..|.|:| |...|        .|:....|.|:..::|..    ||..|  ..:|:..
Human   853 ---LPSPAEAEL-YQYYL--------AQNMNLPNLKMDSAASDA----QFMMS--GFQLDPAGPM 899

  Fly   855 ---TGAAMGIGMAMGMGMSHSNEVSCELSGDPHPLTKTDKWPMAFYSCLVCDCYSTNNLDDLNQH 916
               |.|.:|..:.:.|.:.....||.||........:|:...:..:.|.||:.::|:|||.|..|
Human   900 AAMTPALVGGEIPLDMRLGGGQLVSEELMNLGESFIQTNDPSLKLFQCAVCNKFTTDNLDMLGLH 964

  Fly   917 LLLDRSRQSSSASSEIMVIHNNNYICRLCNYKTNLKANFQLHSKTDKHLQKLNFINHIREGGPQN 981
            :.::|    |.:..|...:..::|.|:||.|.|.||||||||.|||||:||...:.||:|||..|
Human   965 MNVER----SLSEDEWKAVMGDSYQCKLCRYNTQLKANFQLHCKTDKHVQKYQLVAHIKEGGKAN 1025

  Fly   982 EYKMQYQQQQLAANVVQLKCNCCDFHTNSIQKLSLHTQQMRHDTMRMIFQHLLYIVQQSEMHNKS 1046
            |::::.   ....|.|.||||.||::|||::||.|||...||:....:::||    ||.|
Human  1026 EWRLKC---VAIGNPVHLKCNACDYYTNSLEKLRLHTVNSRHEASLKLYKHL----QQHE----- 1078

  Fly  1047 SGSAEDDPQCACPDEDQQLQLQSSKKLLLCQLCNFTAQNIHEMVQHVKGIRHLQVEQFICLQRRS 1111
              |..:...|                ...|.|||::.:....::|||:.::|.:.|....|||..
Human  1079 --SGVEGESC----------------YYHCVLCNYSTKAKLNLIQHVRSMKHQRSESLRKLQRLQ 1125

  Fly  1112 EN--QEIPALNEVFKV-----TEWVMENEDVSLAPGLNLARTTTNDATTDASYAAASSAA----- 1164
            :.  :|...|.::|.:     |:.....|||.   |.:.......:...|....|:||.|
Human  1126 KGLPEEDEDLGQIFTIRRCPSTDPEEAIEDVE---GPSETAADPEELAKDQEGGASSSQAEKELT 1187

  Fly  1165 -VPAIPDVSMFSPTSPSSCATSCDKNLSQIVLPNVNNLGSGVPTTVFKCNLCEYFVQSKSEIAAH 1228
             .||......|..:|.|..::...|...:|           .|..:::|..|:|.....:.:..|
Human  1188 DSPATSKRISFPGSSESPLSSKRPKTAEEI-----------KPEQMYQCPYCKYSNADVNRLRVH 1241

  Fly  1229 IETEHSCAESDEFITIPTNTAALQAFQTAVAAAALAAVHQRCAVINPPTQDTVDEDKDLDTNVSD 1293
            ..|:||                                      :.|.
Human  1242 AMTQHS--------------------------------------VQPM----------------- 1251

  Fly  1294 GPVGIKQERLEQEVDRTTSMDVTKDLASQATDFGAPESPKVAETEVGVQCPLCLENHFREKQYLE 1358
                                                           ::|||| ::....|.:|:
Human  1252 -----------------------------------------------LRCPLC-QDMLNNKIHLQ 1268

  Fly  1359 DHLTSVHSVTRDGLSRLLLLVDQKALKKESTDI--ACPTDKAPYANTNALERAPTPIENTCNVSL 1421
            .|||.:|||..|.:.:|::.|....:...|:..  |...|:...:|.....:.|...|: ...::
Human  1269 LHLTHLHSVAPDCVEKLIMTVTTPEMVMPSSMFLPAAVPDRDGNSNLEEAGKQPETSED-LGKNI 1332

  Fly  1422 IKSTSANPSQSVSLQGLSCQQCEASFKHEEQLLKHAQQNQHFSLQNGEYLCLAASHISRPCFMTF 1486
            :.|.|...|..                     ||.:..:.....::..::|.     .:.|...|
Human  1333 LPSASTEQSGD---------------------LKPSPADPGSVREDSGFICW-----KKGCNQVF 1371

  Fly  1487 RTIPTMISHFQDLHM---SLIISERHVYKYRCKQCSLAFKTQEKLTTHMLYHSMRDATKCSFCQR 1548
            :|...:.:||.::|.   .|.:|:||||||||.||||||||.|||..|..||.:|.||.|..|||
Human  1372 KTSAALQTHFNEVHAKRPQLPVSDRHVYKYRCNQCSLAFKTIEKLQLHSQYHVIRAATMCCLCQR 1436

  Fly  1549 NFRSTQALQKHMEQAH-----------------------------AEDGT--------------- 1569
            :||:.|||:||:|.:|                             |||.|
Human  1437 SFRTFQALKKHLETSHLELSEADIQQLYGGLLANGDLLAMGDPTLAEDHTIIVEEDKEEESDLED 1501

  Fly  1570 ---------PSTRTNS-----------------------PQTPMLST----EETHKHLL------ 1592
                     .|.:.:|                       |..|...|    ..|.|::|
Human  1502 KQSPTGSDSGSVQEDSGSEPKRALPFRKGPNFTMEKFLDPSRPYKCTVCKESFTQKNILLVHYNS 1566

  Fly  1593 -AESHAVEREV-----------SGSDVSPIE-------------LETHL---------------- 1616
             :..|.::|.:           |..|..|.:             ||.|:
Human  1567 VSHLHKLKRALQESATGQPEPTSSPDNKPFKCNTCNVAYSQSSTLEIHMRSVLHQTKARAAKLEA 1631

  Fly  1617 ---------NKETRHLS---PTPMSLD-------------------------------------- 1631
                     |..:..||   |:|:|..
Human  1632 ASGSSNGTGNSSSISLSSSTPSPVSTSGSNTFTTSNPSSAGIAPSSNLLSQVPTESVGMPPLGNP 1696

  Fly  1632 -----------SQSHQKHLATFAALLKQQQCNSDAGGLHPEALSMSTGEMPPQLQGLQNLQ---- 1681
                       .::::|.||...|..:|||        ..:.......:...|.|.|...|
Human  1697 IGANIASPSEPKEANRKKLADMIASRQQQQ--------QQQQQQQQQQQQQQQAQTLAQAQAQVQ 1753

  Fly  1682 -HIQQHFGAVAA-----------AAGLPINPVDMLNIMQFHHLM------SLNFM---NLAPPLV 1725
             |:||.....||           ....|:....:|.:.|..||:      |..|.   .::.|:.
Human  1754 AHLQQELQQQAALIQSQLFNPTLLPHFPMTTETLLQLQQQQHLLFPFYIPSAEFQLNPEVSLPVT 1818

  Fly  1726 FGANAAGNAVSG--------------------PSALNNSITTSTATSA----------------- 1753
            .||........|                    |....|.::.:.:.||
Human  1819 SGALTLTGTGPGLLEDLKAQVQVPQQSHQQILPQQQQNQLSIAQSHSALLQPSQHPEKKNKLVIK 1883

  Fly  1754 --------------SGLGDT----------------HLTSGVSSIP------------------- 1769
                          .|.|:|                .|..|..|.|
Human  1884 EKEKESQRERDSAEGGEGNTGPKETLPDALKAKEKKELAPGGGSEPSMLPPRIASDARGNATKAL 1948

  Fly  1770 -------------------------VDSGK----------------------------------- 1774
                                     .|.|:
Human  1949 LENFGFELVIQYNENKQKVQKKNGKTDQGENLEKLECDSCGKLFSNILILKSHQEHVHQNYFPFK 2013

  Fly  1775 -------------------------------------ATAVPPQ--------------------- 1781
                                                 ..|.|||
Human  2014 QLERFAKQYRDHYDKLYPLRPQTPEPPPPPPPPPPPPLPAAPPQPASTPAIPASAPPITSPTIAP 2078

  Fly  1782 -------TQLNA--------------------------------------------NANSQQLAS 1795
                   |||:.                                            ..|...|..
Human  2079 AQPSVPLTQLSMPMELPIFSPLMMQTMPLQTLPAQLPPQLGPVEPLPADLAQLYQHQLNPTLLQQ 2143

  Fly  1796 NQKRARTRITDDQLKILRAHFDINNSPSEESIMEMSQKANLPMKVVKHWFRNTLFKERQRNKDSP 1860
            ..||.|||||||||::||.:||||||||||.|.||:.|:.||.||:|||||||||||||||||||
Human  2144 QNKRPRTRITDDQLRVLRQYFDINNSPSEEQIKEMADKSGLPQKVIKHWFRNTLFKERQRNKDSP 2208

  Fly  1861 YNFNNPPSTTLNLEEYERTGQAKVTPLNDTCSVAVTGPMTSSTISLPPSGNINLSSKENATSKVL 1925
            |||:|||.|  :|||.:
Human  2209 YNFSNPPIT--SLEELK------------------------------------------------ 2223

  Fly  1926 AAGKANASGPVTFSATVPVSTPLSRPESTNSSGNISDYIGNNIFFGQLGSKEQILPYSLDGQIKS 1990

Human  2224 ----------------------------------------------------------------- 2223

  Fly  1991 EPQDDMIGATDFAYQTKQHSSFSFLKQQQDLVDPPEQCLTNQNADTAQDQSLLAGSSLASNCQSQ 2055
                                           :|
Human  2224 -------------------------------ID-------------------------------- 2225

  Fly  2056 QQINIFETKSESGSSDVLSRPPSPNSGAAGNVYGSMNDLLNQQLENMGSNMGPPKKMQIVGKTFE 2120
                              ||||||.                           |||:
Human  2226 ------------------SRPPSPE---------------------------PPKQ--------- 2236

  Fly  2121 KNVAPMVTSGSVSTQFESNSSNSSSSSSSTSGGKRANRTRFTDYQIKVLQEFFENNSYPKDSDLE 2185
                                        ...|.||::||||||||::|||:||:.|:||||.:.|
Human  2237 ----------------------------EYWGSKRSSRTRFTDYQLRVLQDFFDANAYPKDDEFE 2273

  Fly  2186 YLSKLLLLSPRVIVVWFQNARQKQRKIYENQPNNTLFENEE------TKKQNINYACKKCNLVFQ 2244
            .||.||.|..|||||||||||||.||.||||......|..|      .:..|:||.||||:||||
Human  2274 QLSNLLNLPTRVIVVWFQNARQKARKNYENQGEGKDGERRELTNDRYIRTSNLNYQCKKCSLVFQ 2338

  Fly  2245 RYYELIRHQKNHCFKEENNKKSAKAQIAAAQIAQNLSSEDSNSSMDIHHVGICPPGSAVASHTLS 2309
            |.::||:|||..|:|:|:.:....:|           :|||..:|:     |..|.|:..|..:.
Human  2339 RIFDLIKHQKKLCYKDEDEEGQDDSQ-----------NEDSMDAME-----ILTPTSSSCSTPMP 2387

  Fly  2310 TPGSAAPLPGQYTQHSFGALPSPQHLFAKSSSLTDF---------------SPSTTPTPPQRERS 2359
            :...:||.|......|...|    .|.|::..|..|               :||..|...|.::.
Human  2388 SQAYSAPAPSANNTASSAFL----QLTAEAEELATFNSKTEAGDEKPKLAEAPSAQPNQTQEKQG 2448

  Fly  2360 N--------------------------SLDQIQRPP----------------------------- 2369
            .                          ||..:.:||
Human  2449 QPKPELQQQEQPEQKTNTPQQKLPQLVSLPSLPQPPPQAPPPQCPLPQSSPSPSQLSHLPLKPLH 2513

  Fly  2370 ---------------KFDCDKCELNFNQLEKLREHQLLHLMNPGNICSDVGQNSNPE-------- 2411
                           .:.||:|:|.|...|..:|||.||.::..|      |..:|:
Human  2514 TSTPQQLANLPPQLIPYQCDQCKLAFPSFEHWQEHQQLHFLSAQN------QFIHPQFLDRSLDM 2572

  Fly  2412 --ANFGPFGSIL--QSLQQAAAQQQQQHHQQPPTK-------KRKY----------SDCSSNADE 2455
              ..|.|...:|  |.|..|..|........|.|.       |||.          :|..:..:|
Human  2573 PFMLFDPSNPLLASQLLSGAIPQIPASSATSPSTPTSTMNTLKRKLEEKASASPGENDSGTGGEE 2637

  Fly  2456 MQSLSELEA--SQKKHEYLY-KYFMQNETSQEVKQQFLMQQQQKKLEQGNECDFELDFLTNFYQQ 2517
            .|....|..  :.::.|.|| ||.:.:..::::......:...||.            :...:.|
Human  2638 PQRDKRLRTTITPEQLEILYQKYLLDSNPTRKMLDHIAHEVGLKKR------------VVQVWFQ 2690

  Fly  2518 NELKKVSNYDFLLQYYRTHEEAKSSQQHTFSSS---KKPTIEFLLQYYQLNESKKF-FQLVASPQ 2578
            |...:.....|     |....|::.::..|..:   .|..:|..::....:|:|:. :.|..|..
Human  2691 NTRARERKGQF-----RAVGPAQAHRRCPFCRALFKAKTALEAHIRSRHWHEAKRAGYNLTLSAM 2750

  Fly  2579 IIP---------DVPGYKPSLRIPKSTSDEAPYIGETSLEQATELQREKQDEQLRIDRPSEENDL 2634
            ::.         |:........:|.|:||          .|...|....:..:|     |....|
Human  2751 LLDCDGGLQMKGDIFDGTSFSHLPPSSSD----------GQGVPLSPVSKTMEL-----SPRTLL 2800

  Fly  2635 SMNKNKVENI--------NNNNINVDQSNL-----TETNGGVPSVETKEECTQESSLIAMDDENK 2686
            |.:..|||.|        ::.|:|.||:.|     :..|..:....|.:|..      |.:|...
Human  2801 SPSSIKVEGIEDFESPSMSSVNLNFDQTKLDNDDCSSVNTAITDTTTGDEGN------ADNDSAT 2859

  Fly  2687 YLCTRSKQKD------DKEKSHYLHNLEDFLDATMIE----------NNSQTLTFNDDEKACQKD 2735
            .:.|.:|...      .|.....:...||.|.:.::.          :|..|:.:::........
Human  2860 GIATETKSSSAPNEGLTKAAMMAMSEYEDRLSSGLVSPAPSFYSKEYDNEGTVDYSETSSLADPC 2924

  Fly  2736 ELTQNSNAIEKRSSVSPVNVSSKQNKRLRTTILPEQLNFLYECYQSESNPSRKMLEEISKKVNLK 2800
            ..:..::....:|..|.   .....||.||.:...||..|..|:.....|:....|.:...:.|.
Human  2925 SPSPGASGSAGKSGDSG---DRPGQKRFRTQMTNLQLKVLKSCFNDYRTPTMLECEVLGNDIGLP 2986

  Fly  2801 KRVVQVWFQNSRAKDKKSR--NQRHYAHISDDNSYDGSSGKEVYSDLRSNGITVDTDLETNLQDC 2863
            ||||||||||:|||:|||:  ..:|:.  .:..||:|..                       .:|
Human  2987 KRVVQVWFQNARAKEKKSKLSMAKHFG--INQTSYEGPK-----------------------TEC 3026

  Fly  2864 QLCQV---TQVNIRKHAFSVEHISKMKKLLEQTTELYAQSNGSGSEDNDSDREKRFYNLSKAFLL 2925
            .||.:   .::::|.|.||.:||||:|..:             ||:   .|:||.:::.:....|
Human  3027 TLCGIKYSARLSVRDHIFSQQHISKVKDTI-------------GSQ---LDKEKEYFDPATVRQL 3075

  Fly  2926 QHVVTNATSHAIHTARQDSDVIAEGNCIL 2954
            .             |:|:.|.|.:.|.:|
Human  3076 M-------------AQQELDRIKKANEVL 3091

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
zfh2	NP_524623.2	C2H2 Zn finger	561..581	CDD:275368	15/19 (79%)
		C2H2 Zn finger	616..633	CDD:275368	15/16 (94%)
		C2H2 Zn finger	1515..1542	CDD:275371	17/26 (65%)
		C2H2 Zn finger	1543..1564	CDD:275371	12/20 (60%)
		HOX	1797..1853	CDD:197696	41/55 (75%)
		Homeobox	2158..2210	CDD:278475	37/51 (73%)
		Homeobox	2764..2816	CDD:278475	22/51 (43%)
ZFHX3	NP_001373664.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..78
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	96..128		2/2 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	417..536		19/136 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	588..619		5/30 (17%)
		C2H2 Zn finger	673..693	CDD:275368	15/19 (79%)
		C2H2 Zn finger	728..745	CDD:275368	15/16 (94%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1148..1214		15/68 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1303..1354		10/72 (14%)
		C2H2 Zn finger	1362..1385	CDD:275368	6/27 (22%)
		C2H2 Zn finger	1403..1423	CDD:275371	13/19 (68%)
		C2H2 Zn finger	1431..1452	CDD:275371	12/20 (60%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1490..1529		2/38 (5%)
		C2H2 Zn finger	1547..1571	CDD:275368	4/23 (17%)
		C2H2 Zn finger	1598..1616	CDD:275368	3/17 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1629..1727		13/105 (12%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1865..1938		9/72 (13%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2030..2082		4/51 (8%)
		HOX	2145..2201	CDD:197696	41/55 (75%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2204..2244		27/299 (9%)
		Homeobox	2245..2299	CDD:395001	37/53 (70%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2376..2400		6/23 (26%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2422..2520		8/97 (8%)
		COG5576	2594..2738	CDD:227863	25/160 (16%)
		Nuclear localization signal. /evidence=ECO:0000269\|PubMed:24651376	2615..2617		1/1 (100%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2619..2647		4/27 (15%)
		Homeobox	2645..2698	CDD:395001	9/64 (14%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2771..2796		7/39 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2841..2871		6/35 (17%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	2912..2947		2/37 (5%)
		Homeobox	2950..3003	CDD:395001	22/52 (42%)
		Herpes_BLLF1	<3104..>3191	CDD:282904
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	3137..3267
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	3386..3449
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	3565..3703
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	236	1.000	Domainoid score	I2349
eggNOG	1	0.900	-	-		E1_KOG1146
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	874	1.000	Inparanoid score	I413
Isobase	1	0.950	-	0	Normalized mean entropy	S7393
OMA	1	1.010	-	-		QHG46832
OrthoDB	1	1.010	-	-		D11071at33208
OrthoFinder	1	1.000	-	-		FOG0002899
OrthoInspector	1	1.000	-	-		otm40663
orthoMCL	1	0.900	-	-		OOG6_106078
Panther	1	1.100	-	-	O	PTHR45891
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3541
SonicParanoid	1	1.000	-	-		X1134
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.820