DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Asator and HRR25

DIOPT Version :9

Sequence 1:	NP_651924.2	Gene:	Asator / 43794	FlyBaseID:	FBgn0039908	Length:	1349	Species:	Drosophila melanogaster
Sequence 2:	NP_015120.1	Gene:	HRR25 / 855897	SGDID:	S000006125	Length:	494	Species:	Saccharomyces cerevisiae

Alignment Length:	521	Identity:	148/521 - (28%)
Similarity:	222/521 - (42%)	Gaps:	103/521 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   169 VKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQGKEHVCRFI 233
            |..::::.||||.|.||:||.|.:||:.|:||:|:||.|.....|..|..|.:.|.|...:....
Yeast     5 VGRKFRIGRKIGSGSFGDIYHGTNLISGEEVAIKLESIRSRHPQLDYESRVYRYLSGGVGIPFIR 69

  Fly   234 GCGRNDRFNYVVMQLQGKNLAEL-----RRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRD 293
            ..||...:|.:|:.|.|.:|.:|     ||      ||..|.:.|.||:...|:.||...|:|||
Yeast    70 WFGREGEYNAMVIDLLGPSLEDLFNYCHRR------FSFKTVIMLALQMFCRIQYIHGRSFIHRD 128

  Fly   294 IKPSNF--SVGRLPYNCRRVYMLDFGLARQYTTGTGEVRCP-RAAAGFRGTVRYASINAHRNREM 355
            |||.||  .|||   ....|:::||||:::|.........| |......||.||||:|.|...|.
Yeast   129 IKPDNFLMGVGR---RGSTVHVIDFGLSKKYRDFNTHRHIPYRENKSLTGTARYASVNTHLGIEQ 190

  Fly   356 GRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKH-----------LPSDLKQ 409
            .|.|||.||.|:|:.|..|.|||:.:|...:    |:||| ||:.|.           ||.:.::
Yeast   191 SRRDDLESLGYVLIYFCKGSLPWQGLKATTK----KQKYD-RIMEKKLNVSVETLCSGLPLEFQE 250

  Fly   410 FLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDW------------------EKVDSTA 456
            ::.:.::|.:.::|||..|..||:....:........:||                  ||.|..|
Yeast   251 YMAYCKNLKFDEKPDYLFLARLFKDLSIKLEYHNDHLFDWTMLRYTKAMVEKQRDLLIEKGDLNA 315

  Fly   457 IGNISATGNPSIPIKSDYMHGNITQMTVAASNASGTEYIRKRAEIETAHITATDPLNIKEKVDKN 521
            ..|.::..| |...||:..  |..::.......:...|.:.    |..|  ...|..||::...|
Yeast   316 NSNAASASN-STDNKSETF--NKIKLLAMKKFPTHFHYYKN----EDKH--NPSPEEIKQQTILN 371

  Fly   522 CNATSLAQPAKGSGEPMVQHGNAANNQNITSKGL----QQQSTLTNSQVAIANIQSAPSMIERED 582
            .||.| :.|     |.::         |...||:    |||   ...||..:..|..|..::::
Yeast   372 NNAAS-SLP-----EELL---------NALDKGMENLRQQQ---PQQQVQSSQPQPQPQQLQQQ- 417

  Fly   583 VQYTKLEEGAPTKFITMKPNGECDNVDIAAKCIFEQKHVEANDDIVGRASLSGVEQHYKSQIKKH 647
                              |||:..|.........:|:..:.....|..|:....:  |..||..:
Yeast   418 ------------------PNGQRPNYYPEPLLQQQQRDSQEQQQQVPMATTRATQ--YPPQINSN 462

  Fly   648 N 648
            |
Yeast   463 N 463

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Asator	NP_651924.2	STKc_TTBK	172..433	CDD:270919	101/279 (36%)
Asator	NP_651924.2	S_TKc	173..414	CDD:214567	95/259 (37%)
HRR25	NP_015120.1	PKc_like	8..282	CDD:419665	102/287 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810