DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Asator and vrk1

DIOPT Version :9

Sequence 1:	NP_651924.2	Gene:	Asator / 43794	FlyBaseID:	FBgn0039908	Length:	1349	Species:	Drosophila melanogaster
Sequence 2:	NP_998550.1	Gene:	vrk1 / 406694	ZFINID:	ZDB-GENE-040426-2709	Length:	425	Species:	Danio rerio

Alignment Length:	444	Identity:	118/444 - (26%)
Similarity:	198/444 - (44%)	Gaps:	78/444 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   143 DGILVDVKAKESVKMTSEDLLQPGHVV----KERWKVVRKIGGGGFGEIY----EGQDLITRE-Q 198
            ||:   .||:...|....:....|.|:    |::||:...:|.||||.:|    :....:|.: .
Zfish     7 DGV---KKARAPAKRKLAEEFPSGEVLTDNAKKKWKLGSAVGQGGFGLLYLANEDSSGPVTADAP 68

  Fly   199 VALKVESA-------------RQPKQVLKMEVAVLKKLQGKEH--VCRFIGCGRND----RFNYV 244
            ..:|||.:             |..|..|   :....|.:..|:  |.::.|.|.::    |:.::
Zfish    69 YVIKVEPSDNGPLFSELKFYMRAAKPDL---IGAWMKSKKMEYLGVPKYWGSGFHEKNGKRYRFM 130

  Fly   245 VMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPY-NC 308
            ||...|.:|.:|.....: .||....|:|||::|..:|.||...::|.|||.||.   .|.| |.
Zfish   131 VMDRFGTDLQKLFEGNGK-KFSRKLVLQLGLRLLDILEYIHDHEYVHADIKASNL---LLSYTNP 191

  Fly   309 RRVYMLDFGLARQYT-TGTGE------VRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFY 366
            .:|:::|:|||.:|. .|..:      .||      ..||:.:.||:||:.....|..||..:.|
Zfish   192 NQVFLVDYGLAYRYAPEGVPKEYKEDPKRC------HDGTIEFTSIDAHKGVSPSRRADLEIMGY 250

  Fly   367 MLVEFVNGQLPWR-KIKDKEQVGLTKEKYDHRI--LLK------HLPSDLKQFLEHIQSLTYGDR 422
            .:::::..:|||. |::|...|..:|.:....|  .||      ::|:::.:|::.::.|.|.||
Zfish   251 CMIQWLCSRLPWEDKLQDPLYVRDSKLRCRDNIDEFLKSCFASGNIPAEMGKFMQEVKVLGYTDR 315

  Fly   423 PDYAMLIGLFERCMKRRGVKESDPYDWEKVDSTAIGNISATGNPSIPIKSDYMHGNITQMTVAAS 487
            |||..|.|:.:     :|:|.....|.:|:|...     ||.:.|:|...........:...:|.
Zfish   316 PDYDKLRGILQ-----QGLKSIGSTDDKKLDFGV-----ATNSTSLPSVKTPKRKKAEEKGQSAD 370

  Fly   488 NASGTEYIRKRA----EIETAHITATDPLNIKEKVDKNCNATSLAQPAKGSGEP 537
            ....|...::||    |:..|..||:.   .|..|.|...|:|.....|..|.|
Zfish   371 ETDSTPAKKRRAPQKKEVNGAKKTASP---AKRPVKKETQASSEPAVKKSRGRP 421

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Asator	NP_651924.2	STKc_TTBK	172..433	CDD:270919	85/301 (28%)
Asator	NP_651924.2	S_TKc	173..414	CDD:214567	76/281 (27%)
vrk1	NP_998550.1	PKc_like	27..327	CDD:304357	88/317 (28%)
		SPS1	37..>265	CDD:223589	67/240 (28%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	343..425		20/87 (23%)
		GAGA_bind	<373..>424	CDD:283799	15/52 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.810