Protein Alignment Asator and Ttbk2

DIOPT Version :10

• Sequence 1: NP_651924.2
• Gene: Asator / 43794
• FlyBaseID: FBgn0039908
• Length: 1349
• Species: Drosophila melanogaster
• Sequence 2: XP_006234899.2
• Gene: Ttbk2 / 311349
• RGDID: 1311661
• Length: 1311
• Species: Rattus norvegicus
• Alignment Length: 1279
• Identity: 411/1279 - (32%)
• Similarity: 572/1279 - (44%)
• Gaps: 287/1279 - (22%)

  Fly   161 DLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVALKVESARQPKQVLKMEVAVLKKLQG 225
            |:|..|.:|||||||:||||||||||||:..|::|||.||||||||:||||||||||||||||||
  Rat    78 DILSVGILVKERWKVLRKIGGGGFGEIYDALDMLTRENVALKVESAQQPKQVLKMEVAVLKKLQG 142

  Fly   226 KEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFL 290
            |:|||||||||||||||||||||||:|||:|||:|.||.|::|||||||.|||::||||||||||
  Rat   143 KDHVCRFIGCGRNDRFNYVVMQLQGRNLADLRRSQSRGTFTISTTLRLGKQILESIESIHSVGFL 207

  Fly   291 HRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTTGTGEVRCPRAAAGFRGTVRYASINAHRNREM 355
            |||||||||::||.|..||:.:|||||||||:|...|:||.|||.||||||||||||||||||||
  Rat   208 HRDIKPSNFAMGRFPSTCRKCFMLDFGLARQFTNSCGDVRPPRAVAGFRGTVRYASINAHRNREM 272

  Fly   356 GRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLKHLPSDLKQFLEHIQSLTYG 420
            |||||||||||||||||.|||||||||||||||..||:||||::|||||.:...||:||.||.|.
  Rat   273 GRHDDLWSLFYMLVEFVVGQLPWRKIKDKEQVGSIKERYDHRLMLKHLPPEFSTFLDHISSLDYF 337

  Fly   421 DRPDYAMLIGLFERCMKRRGVKESDPYDWEKVDSTAIGNISATGNPSIPIKSDYMHGNITQMTVA 485
            .:|||.:|..:|:..:|..||.||||:||||  |...|:::.|...:.|    .:|..:|...:.
  Rat   338 TKPDYQLLTSVFDNSIKTFGVIESDPFDWEK--SGTDGSLTTTTTSATP----QLHTRLTPAAIG 396

  Fly   486 ASNASGT--EYIRKRAEIETAHITATDPLNIKEKVDKNCNATSL-AQPAK--GS-GEPMVQHGNA 544
            .:||:..  :.:|:.          ||.:...|::....|.... ..|.|  || |.|..|..:.
  Rat   397 IANATPIPGDLLREN----------TDEVFPDEQLSDGENGIPAGVSPDKLPGSLGHPRPQEKDV 451

  Fly   545 AN----NQNITSKGLQQQST-LTNSQVAIANIQSAPSMIE--REDVQYTKLEEGAP--------- 593
            ..    |:|....|:.:.:| ..||...:..|.:|||:..  |...:.|:.:...|
  Rat   452 WEEMDINKNKIKLGICKAATEEENSHGQVNGILNAPSLGSPIRVRSEITQPDRDVPLVRKLRSIH 516

  Fly   594 ----TKFITMKPNGECDNVDIAAKCIFEQKHVEANDDIVGRASLSGVEQHYKSQIKKHNSPEIAN 654
                .|.:|::|..:.|            |.:|...:.:.:.|.:|         |:...|.:.:
  Rat   517 SFELEKRLTLEPKPDTD------------KFLETCMEKMQKDSSAG---------KEPVLPALPH 560

  Fly   655 K----QIQRTGTVTN-------DKTSEVNRSTEEQKSTFGRLRVLTAPPMSVHDLPSGGGHSHQV 708
            |    .:.||..|.:       |.:...:.:|.||..                   .||.|....
  Rat   561 KPCVPAVPRTDHVWHYDEEYPPDASKPASANTPEQAD-------------------GGGSHGFIA 606

  Fly   709 SDLSG-KQDPYAATSNAAPIGINSSSTKFGSQHGQIFGLAAMPPINRRSATSTNLRPSSSASQ-- 770
            .:||. ||:            ::|.......:...:........:..::..|    ||....:
  Rat   607 VNLSSCKQE------------VDSKEWVIVDKEQDLRDFRTNEVLGHKTTGS----PSDEEPEVL 655

  Fly   771 RINSGSTIGGAVGNGSNTARSSVAGDHSVTQFALIDDENVSALQQVTKGGALTLASQWKSQFDDS 835
            ::..||.....:..|..|....:..:.|....||..:...:|..::.. ..|.|.:...|||...
  Rat   656 QVLEGSPQDEKIQVGPWTDNQHLKKESSGVILALSAECPATAASELYT-DRLDLQAGAASQFITV 719

  Fly   836 EDTTDNEWNREHQLQPNLEQLIKLDISLPLNEAKPFPQHGVAGTGKL-----INPPGEAKG-RPK 894
            ..|:..|...|..|                 .|...|:..||.|...     ..|..|.|. :|.
  Rat   720 TPTSPMEAQAEGPL-----------------TAITIPRPSVASTQSTSGSFHYGPQPEKKDLQPL 767

  Fly   895 RYTLNI-TGIENYEALRIS---IPNCWSEPAMG---NVLRKGLEPPAVQQAAFDDTVYR-MDIAR 951
            ..|:.: :..||:..|.::   :.:..|...:|   :.:..|:.|......|..|...| :..:.
  Rat   768 EPTVELFSPRENFSGLAVTEGELGSGGSRVDLGLQIDHIGHGMLPNMKDGDASQDLGPRDLPDSN 832

  Fly   952 NVCVRETYSEITHLARPSTSSVLRNRLPSPFKKDSALQLNSTN--DSLDKSRH--RNSLPNVSVN 1012
            .:.|:|.                 ..||...::.|.| |.|.|  :.|:|.:|  ..|||...|.
  Rat   833 RLVVKEF-----------------ENLPGETEEKSIL-LGSDNEDEKLNKGQHCIEISLPGDLVT 879

  Fly  1013 DIFDDLQMKLNLDLGSAIQENNCCISGRLEIRVIP-KDTSHPDDSVYYDAMGAVKNTPTANEGHD 1076
            ...|.......||           :|......|:| :|.:|  :.:...|:|..:.:|.|.:.|
  Rat   880 TERDQSATTEPLD-----------VSKTQNFSVVPNQDKNH--EIMKLLAVGTSEMSPQAIDPH- 930

  Fly  1077 HSDQAVNNCDEMEATSAVIAFPNKSISKIMSPPGRDATEERTGASLCSLYSAGVNKLKLNGNTAP 1141
                |.....::........|  |..:|..|.||:.      |.....|:..|..:     ..||
  Rat   931 ----AEGQIGQVATVQKHKLF--KDDTKSESLPGQQ------GDLATFLHQEGKRE-----KVAP 978

  Fly  1142 RTQFKKGSTDGFGE-----NESEFDFP----------LLNPSKIPVRQSKCASWAGADFISASKP 1191
            |.          ||     :|||...|          :...|:|||    .|....:.|.|:|..
  Rat   979 RN----------GELYHCVSESEHGPPTRKDMLRSSLVTRHSRIPV----LAQEIDSTFESSSAV 1029

  Fly  1192 LESAEVPQEIPYHPQSDTTYSVIDSIPVRKTTYSIALECPPNISDLTPGLRRRRES--------- 1247
            ....::.|:..|.|:       |..:.|.|..:...|      .||:....:..|.
  Rat  1030 SAKEKLLQKKAYQPE-------IVKLLVEKRQFKSFL------GDLSSASEKLMEEKLAAAAVPF 1081

  Fly  1248 TEGKYVTDPTQLPLKFQRPRS---------RTSSRTRGIPNAMLENSDDNGTVMSAEKTGHGHVV 1303
            :|.:.....::|.:..|..||         .:.||...||..
  Rat  1082 SEEEVFAPFSRLAVDPQLSRSVEDGFLSPIVSQSRKSKIPRP----------------------- 1123

  Fly  1304 KTEGVKNFTTSENSSEVNPKCTISPPPGDPKIEN--SARLRRYR 1345
                |...:|.:.:|..:|:....||||.|.:..  .||||||:
  Rat  1124 ----VSWVSTDQINSSASPQFLPRPPPGKPPVRPGVEARLRRYK 1163

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Asator	NP_651924.2	STKc_TTBK	172..433	CDD:270919	204/260 (78%)
Ttbk2	XP_006234899.2	STKc_TTBK2	89..350	CDD:271031	204/260 (78%)