Protein Alignment Asator and Grk2

DIOPT Version :9

• Sequence 1: NP_651924.2
• Gene: Asator / 43794
• FlyBaseID: FBgn0039908
• Length: 1349
• Species: Drosophila melanogaster
• Sequence 2: NP_036908.2
• Gene: Grk2 / 25238
• RGDID: 2062
• Length: 689
• Species: Rattus norvegicus
• Alignment Length: 645
• Identity: 140/645 - (21%)
• Similarity: 220/645 - (34%)
• Gaps: 229/645 - (35%)

  Fly    95 LQRSATLPAKHNRLGVRSRVTFKVPSSNLPAQDSY--------SHQPRNQVAVAAKDGILVDVKA 151
            :::...|..:..|: ||||..|          |||        || |.::.|.....|.||.
  Rat    89 IKKYEKLETEEERV-VRSREIF----------DSYIMKELLACSH-PFSKNATEHVQGHLVK--- 138

  Fly   152 KESVKMTSEDLLQP----------GHVVKE-----------RWK--------------VVRKIGG 181
                |....||.||          |.|..:           :||              |.|.||.
  Rat   139 ----KQVPPDLFQPYIEEICQNLRGDVFHKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGR 199

  Fly   182 GGFGEIYEGQDLITREQVALKVESARQPK----QVLKMEVAVLKKLQGKEHVCRFIGC-----GR 237
            |||||:|..:...|.:..|:|....::.|    :.|.:...::..|..... |.||.|     ..
  Rat   200 GGFGEVYGCRKADTGKMYAMKCLDKKRIKMKQGETLALNERIMLSLVSTGD-CPFIVCMSYAFHT 263

  Fly   238 NDRFNYVVMQLQGKNLAELRRAQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVG 302
            .|:.::::..:.|.:|.  ......|.||.:.......:|:..:|.:|:...::||:||:|..:.
  Rat   264 PDKLSFILDLMNGGDLH--YHLSQHGVFSEADMRFYAAEIILGLEHMHNRFVVYRDLKPANILLD 326

  Fly   303 RLPYNCRRVYMLDFGLARQYTTGTGEVRCPRAAAGFRG---------TVRYASINAHRNREMGRH 358
            ...:    |.:.|.|||..::.     :.|.|:.|..|         .|.|.|           .
  Rat   327 EHGH----VRISDLGLACDFSK-----KKPHASVGTHGYMAPEVLQKGVAYDS-----------S 371

  Fly   359 DDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDHRILLK--HLPSDLKQFLEHIQSLTYGD 421
            .|.:||..||.:.:.|..|:|:.|.|:     |.:.|...|..  .||.   .|...::||
  Rat   372 ADWFSLGCMLFKLLRGHSPFRQHKTKD-----KHEIDRMTLTMAVELPD---SFSPELRSL---- 424

  Fly   422 RPDYAMLIGLFERCMKRR---------GVKESDPY----DWEKVDSTAIGNISATGNPSIPIKSD 473
                  |.||.:|.:.||         .|||| |:    ||:.|      .:.....|.||.:.:
  Rat   425 ------LEGLLQRDVNRRLGCLGRGAQEVKES-PFFRSLDWQMV------FLQKYPPPLIPPRGE 476

  Fly   474 YMHGNITQMTVAASNASGTEYIRKRAEIETAHITATD---------PLNIKEK------------ 517
            .             ||:....|....|.:|..|...|         ||.|.|:
  Rat   477 V-------------NAADAFDIGSFDEEDTKGIKLLDSDQELYRNFPLTISERWQQEVAETVFDT 528

  Fly   518 VDKNCNATSLAQPAKGS----------GEPMVQHG--NAANNQNIT-----------------SK 553
            ::...:.....:.||..          |:..:.||  :...|..:|                 .:
  Rat   529 INAETDRLEARKKAKNKQLGHEEDYALGKDCIMHGYMSKMGNPFLTQWQRRYFYLFPNRLEWRGE 593

  Fly   554 GLQQQSTLTNSQVAIANIQSAPSMIEREDVQYTKLEEGAPTKFITMKPNG------ECDN 607
            |...||.||              |.|.:.|:.|:::|   .|.:.:|..|      :||:
  Rat   594 GEAPQSLLT--------------MEEIQSVEETQIKE---RKCLLLKIRGGKQFVLQCDS 636

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Asator	NP_651924.2	STKc_TTBK	172..433	CDD:270919	69/294 (23%)
		S_TKc	173..414	CDD:214567	64/274 (23%)
Grk2	NP_036908.2	N-terminal	1..190		26/119 (22%)
		RGS_GRK2_GRK3	30..186	CDD:188701	26/115 (23%)
		STKc_GRK2	190..510	CDD:271125	88/380 (23%)
		PH_GRK2_subgroup	553..670	CDD:269946	20/101 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910