DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Asator and F59A6.4

DIOPT Version :9

Sequence 1:	NP_651924.2	Gene:	Asator / 43794	FlyBaseID:	FBgn0039908	Length:	1349	Species:	Drosophila melanogaster
Sequence 2:	NP_494922.2	Gene:	F59A6.4 / 173865	WormBaseID:	WBGene00019086	Length:	762	Species:	Caenorhabditis elegans

Alignment Length:	350	Identity:	108/350 - (30%)
Similarity:	177/350 - (50%)	Gaps:	42/350 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 KAKESVKMTSEDLLQPGHVV-----KERWKVVRKIGGGGFGEIYEGQDLITREQ------VALKV 203
            |.|:..:.|.:.|.: |.|:     .:.|||:..:|.||||::|:    :.||.      .|||.
Worm   417 KGKKPKRPTRKKLAK-GDVILGVGATDGWKVINLLGSGGFGDVYK----VHRESQPITKCYALKT 476

  Fly   204 ESARQPKQV--LKMEVAVL-----KKLQGK-EHVCRFIGCGRNDRF--NYVVMQLQGKNLAELRR 258
            ||....|:.  ||:||.|:     ||.:.| ::...|:..|:.::.  .||||.|.|.:|.::||
Worm   477 ESEEGEKRYLRLKIEVTVMMKTAEKKKENKFKNFIEFVDRGKCEQLKCKYVVMGLVGPSLEDIRR 541

  Fly   259 AQPRGAFSLSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYT 323
            ....|:||..|:..:.:|.:.|::.:||:|:|||||||:|::|| |......|||||||:|:.|.
Worm   542 KYLLGSFSKHTSFNVAIQTVTALQDLHSIGYLHRDIKPANYAVG-LEDREDTVYMLDFGIAKLYV 605

  Fly   324 TGTGEVRCPRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQ--LPWRKIKDKEQ 386
            ...||.:..|....|.||:|||.......:|.||.|||.:..|::.:.::..  :|||.:...::
Worm   606 DENGEHKVKRKKVKFLGTLRYACRACMMQQEQGRKDDLETWIYLVFDLMDESHGMPWRSLCSPKE 670

  Fly   387 VGLTKEKYDHRILLKHLPSDLKQ---FLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYD 448
            :..:|.::........:.:.||:   .:.::.::.|...|||..:|...:......|.|.|...|
Worm   671 ILKSKNEFFTNFDSSSVSATLKRLKGLVSYVDNMQYETTPDYDYIINFLKTTATEAGAKISKKLD 735

  Fly   449 WEKVDSTAIGNISATGNPSIPIKSD 473
            |       ||.:.   |.....:||
Worm   736 W-------IGKLK---NKEFDSESD 750

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Asator	NP_651924.2	STKc_TTBK	172..433	CDD:270919	92/281 (33%)
Asator	NP_651924.2	S_TKc	173..414	CDD:214567	87/261 (33%)
F59A6.4	NP_494922.2	PKc_like	120..372	CDD:304357
		SPS1	121..>274	CDD:223589
		SPS1	443..>627	CDD:223589	72/188 (38%)
		PKc_like	444..720	CDD:304357	92/280 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160160912
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11909
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.840