Protein Alignment Asator and ttbk1a

DIOPT Version :9

• Sequence 1: NP_651924.2
• Gene: Asator / 43794
• FlyBaseID: FBgn0039908
• Length: 1349
• Species: Drosophila melanogaster
• Sequence 2: XP_009304405.1
• Gene: ttbk1a / 100332125
• ZFINID: ZDB-GENE-100609-4
• Length: 1298
• Species: Danio rerio
• Alignment Length: 1403
• Identity: 417/1403 - (29%)
• Similarity: 601/1403 - (42%)
• Gaps: 348/1403 - (24%)

  Fly   137 VAVAAKDGILVDVKAKESVKMTSEDLLQPGHVVKERWKVVRKIGGGGFGEIYEGQDLITREQVAL 201
            :|.|.:|...::..|::      :|:|.|..:||:||||::||||||||||||..||:|||.|||
Zfish    20 LAPALQDNANMNGTAEQ------QDILPPHCMVKDRWKVLKKIGGGGFGEIYEALDLLTRENVAL 78

  Fly   202 KVESARQPKQVLKMEVAVLKKLQGKEHVCRFIGCGRNDRFNYVVMQLQGKNLAELRRAQPRGAFS 266
            |||||:|||||||||||||||||||.|||:||||||||:||||||||||:|||:|||:||||.|:
Zfish    79 KVESAQQPKQVLKMEVAVLKKLQGKNHVCKFIGCGRNDKFNYVVMQLQGRNLADLRRSQPRGTFT 143

  Fly   267 LSTTLRLGLQILKAIESIHSVGFLHRDIKPSNFSVGRLPYNCRRVYMLDFGLARQYTTGTGEVRC 331
            :|||||||.|||::||:||||||||||||||||::||||...|:.||||||||||||...||||.
Zfish   144 MSTTLRLGKQILESIEAIHSVGFLHRDIKPSNFAMGRLPSTFRKCYMLDFGLARQYTNTNGEVRP 208

  Fly   332 PRAAAGFRGTVRYASINAHRNREMGRHDDLWSLFYMLVEFVNGQLPWRKIKDKEQVGLTKEKYDH 396
            ||..|||||||||||:|||:|:||||||||||||||||||..|||||||||||||||..||:|||
Zfish   209 PRTVAGFRGTVRYASVNAHKNKEMGRHDDLWSLFYMLVEFAAGQLPWRKIKDKEQVGQIKERYDH 273

  Fly   397 RILLKHLPSDLKQFLEHIQSLTYGDRPDYAMLIGLFERCMKRRGVKESDPYDWEKVDSTAIGNIS 461
            |:||||:||:...||||:.:|.|..:|||.:|:.:||..||.|.:.|::||||||..:..|  ||
Zfish   274 RMLLKHMPSEFNVFLEHVLALDYYTKPDYQLLMSVFENSMKERIITENEPYDWEKSGTETI--IS 336

  Fly   462 ATGNPSIPIKSDYMHGNITQMTVAASNASGTEYIRKRAEIETAHITA---------TDPLNIKEK 517
            || .|                |.|..|...|     .|.:...::|.         ||.:...|.
Zfish   337 AT-TP----------------TAAQQNTRPT-----AAMVGVINVTPMPGDLPRENTDDVVQDEH 379

  Fly   518 VDKNCNATSL--AQPAKGSGEP----------------MVQHGNAANNQN--------------I 550
            :....||..:  .:|..||..|                .:..|.....::              :
Zfish   380 LSDQENAPPIPSGRPVDGSQMPTDADGWEETDFNRNKLRINLGKGGQEEDGSRGVCPVSPQRGGL 444

  Fly   551 TSKGLQQQS---TLTNS----------------QVAIANIQSAPS----------MIE------R 580
            .|.|:|..|   ...||                |.:..:|..:||          |:.      |
Zfish   445 DSPGMQVHSIRYRRVNSPESDRMSAADGRDGYGQRSRMDILGSPSRHVYSSQPAQMLSVDGCRGR 509

  Fly   581 EDVQYTKLEEGAPTKFITMKPNGECDNVDIAAKCIFEQKHVEAND--DIVG-RASLSGVEQHYKS 642
            .:...:..:|.....||...|..|.::.| :.:.:...|.:|..|  .:.| ..:.||.......
Zfish   510 NEASASVDQEAHSNAFIRSVPLAEEEDFD-SKEWVIIDKEMELRDFHHLPGAEPTTSGTTDEEPE 573

  Fly   643 QI---------KKH--NSPEIANKQIQRTGTVTNDKTSE-VNRSTEEQ---KSTFGRLRVLTAPP 692
            ::         ::|  |.|.:      ||.|...::|:. :...|||:   :|..|:...:.:|.
Zfish   574 ELRPLEEGDDRRRHRGNDPSV------RTKTSHGERTTRGMLPLTEEETSRRSGKGQSTSMESPA 632

  Fly   693 MS-VHDLPSGGGHSHQVSDLSGKQDPYAATSNAAPIGINSSSTKFGSQHGQIFGLAAMPPINRRS 756
            .| .|.||||...... :|.:|.| ..|.|.:...:......||..|...::|.:  :|.:..:.
Zfish   633 QSPCHSLPSGRPRRRD-ADNNGPQ-RQAPTPSEPLLSPTDYRTKSPSSEKEMFHI--LPKLQAKR 693

  Fly   757 ATSTNLRPSSSASQRINSGSTIGGAVGNGSNTARSSVAGDHSVTQFALIDDENVSALQQVTKGGA 821
            |....:..:.|..||....:|.......|..        |..||:.......:..:.::...|..
Zfish   694 ADFLTVMLTGSLHQRRAFTATPPETQDEGPR--------DDDVTKSESSSGASEKSTERSQDGAP 750

  Fly   822 LTLASQWKSQFDDSEDTTDNEWNREHQLQPNLEQLIKLDISLPLNEAKPFPQHGV-----AGTGK 881
            .||.:       |.......|......:.|:.|.:....:.....:.|..|...:     .|.|.
Zfish   751 STLVA-------DDPQKESKEPGSVADVDPDQEDVSNTLVLFSPGDTKKSPNAIIRAEVDQGVGS 808

  Fly   882 LINPPGEAKGRPKRYTLNITGIENYEALRISIPNCWSEPAMGNVLRKGLEPPAVQQAAFDDTVYR 946
            ...|..|.:|:.:        ::..|.::.:     ..|..|.........|.:|.:....|:..
Zfish   809 FDAPQNENQGQSE--------VQKQEDIKQA-----ERPIDGRQADVTGFDPFIQSSKPVVTIST 860

  Fly   947 MDIARNVC-------VRETY---SEITHLARPSTSS-----VLR---NRLPSPFKKD-------- 985
            ..:|....       |.:|:   :|.|||...|:||     ||:   .:|.|...||
Zfish   861 TPVASASIASPLFSKVEQTFVHIAETTHLNVMSSSSGQVLEVLQEVEGKLQSKLTKDKPEPGGGA 925

  Fly   986 SALQLNSTNDSLDKSRHRNSLPNVSVNDIFDDLQMKLNLDLGSAIQENNCCISGRLEIRVIPKDT 1050
            :.:|....:..|.:   .:.:|||....:.::..:|         |||
Zfish   926 ACVQSEVISQILTE---ESQVPNVLDGSLPNESTVK---------QEN----------------- 961

  Fly  1051 SHPDDSVYYDAMGAVKNTPTANEGHDHSDQAVNNCDEMEATSAV---IAFPNKSISKIMSP---- 1108
              |.|.:...:|..:....|.:...|...:     :|::..|.|   ::.|.:..|:...|
Zfish   962 --PTDPLCVQSMEPIIQDSTIDSNQDEKPK-----EEIQEGSTVPDIVSKPPRPRSRSRIPILVP 1019

  Fly  1109 ---PGRD---ATEER---------TGASLCSLYSAGVNKLKLNGNTA--------PRTQFKKGST 1150
               ||.:   :|:||         ....:...:..| ..::||..|:        |:...:..||
Zfish  1020 EEEPGSEKSLSTKERMRRRVMQQDLARQVVERHRQG-RWIRLNSRTSSSLSSGDEPKRPSETLST 1083

  Fly  1151 DGFGENESEFDFPLLNPSKIPVRQSKCASWAG------------ADFISASKPL---ESAEVPQE 1200
            .|..|:..|.| ..||..|....:.....|..            :..:..:.||   |:|::.|:
Zfish  1084 TGSEEDVLESD-DSLNKLKKEAEEKHQTGWHSRIPRPVTPIRKPSTKLVVAPPLSQPEAAKLEQK 1147

  Fly  1201 I---------------PYHPQSDTTYSVIDSIPVRKTTYSIALECPPNISDLTPGLRRRREST-- 1248
            .               .:|.:|.:|.|        .:|......|.|  ....|...||..||
Zfish  1148 ASNGPKVQSQSGSSAPAFHARSKSTLS--------HSTMPSGSNCMP--LSCIPAASRRSLSTAN 1202

  Fly  1249 ---EGKYVTDPT------------------------QLPLKFQRPRSRTSS------RTRGIPNA 1280
               ....:..|:                        :||||     |||::      .|:..||.
Zfish  1203 CTFSSARIASPSPHRLHLRTAVIESRKQPFALRTTVELPLK-----SRTTTCSNPAKDTKPSPNK 1262

  Fly  1281 MLENSDDNGTVMSAEKTGHGHVVKTEGVKNFTTSENSS 1318
            ....:..|.|..|.:...     .....|..:||.|::
Zfish  1263 ATNTTVRNRTKASTQSKN-----TVPAKKEKSTSNNAA 1295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Asator	NP_651924.2	STKc_TTBK	172..433	CDD:270919	201/260 (77%)
		S_TKc	173..414	CDD:214567	193/240 (80%)
ttbk1a	XP_009304405.1	PKc_like	49..310	CDD:304357	201/260 (77%)
		Pkinase	50..295	CDD:278497	194/244 (80%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	410	1.000	Domainoid score	I658
eggNOG	1	0.900	-	-		E1_KOG1164
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0002285
OrthoInspector	1	1.000	-	-		otm25618
orthoMCL	1	0.900	-	-		OOG6_101431
Panther	1	1.100	-	-	O	PTHR11909
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3595
SonicParanoid	1	1.000	-	-		X1513
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.840