Protein Alignment bip2 and MESR4

DIOPT Version :9

• Sequence 1: NP_651923.2
• Gene: bip2 / 43793
• FlyBaseID: FBgn0026262
• Length: 1406
• Species: Drosophila melanogaster
• Sequence 2: NP_001097359.1
• Gene: MESR4 / 36986
• FlyBaseID: FBgn0034240
• Length: 2171
• Species: Drosophila melanogaster
• Alignment Length: 1761
• Identity: 311/1761 - (17%)
• Similarity: 530/1761 - (30%)
• Gaps: 626/1761 - (35%)

  Fly    22 IGYSC-TLSAPLELLQDILQKFVQEFARDMHRHMEHANRIEPNLKDARLSIKNLSINVQELLDYI 85
            :|.:| |..:|   .:|:::   ||...|....::     ||.         ::|:|.|    ::
  Fly   141 LGANCLTTGSP---SKDLVK---QELVEDKSEELK-----EPT---------SISLNEQ----FL 181

  Fly    86 GNVEPVGFIRDVPQFPIGKSVNMNFLKPGSAETLTRPVYIFEYLPPMQDPELREIPADVQKEFSE 150
            .::|....:.|       ||.::       :||      ..|:|...::.....:.|:.:.|..|
  Fly   182 DDIELKTEVED-------KSDSL-------SET------HMEFLTDSEEQPSESLGANHESEIDE 226

  Fly   151 KQEFCSKAEYSSTNAADK-LGAKHIDS-------ISPNTVINFRSNAFELDVGS----SVREMSS 203
            |.:.....|..|....|| ..:.:.||       :....|||..:::   :.|.    |:::..|
  Fly   227 KVDHFQPKESDSNEVEDKYFQSANEDSESEIEETVYTPPVINLETDS---ESGDKEFISIKDNES 288

  Fly   204 VVM---------TTGGFISPAIEGKLPEDIIPDIVEKFLGLDAPFSPTIIVNSLQ-----KSPQL 254
            .|:         .|.|.:..|..|:......|::       |...|.||.|.||:     .||.|
  Fly   289 PVLEIEGGTEKSQTSGDLYQADVGEYASTAPPEV-------DETTSQTIGVPSLEGSDTLDSPSL 346

  Fly   255 ALSDRDKTVNPRKIIPSETKIFKQNAALLTSGHSESSIIYASNNHTMLTVTTPKKN--RKQKHDL 317
            .: |.|...:.....|:..||   .:.:....||:|..:   ..||:..|...|.|  .|...:.
  Fly   347 TM-DVDLPCSEDGAPPNVIKI---ESDMEDEAHSDSVKL---KEHTVEVVPLIKLNGAHKALKEE 404

  Fly   318 ICEPGQSELLTNPFEKAQEKSQRKALKMYKQTSKNQRDSSINQIQNM--------KKLKKKFNRG 374
            ..|.|:.|.:.:|.|:.::..::..:..:...:..:.|::.:|:..:        .:.:...:|.
  Fly   405 KLEDGEVEEVEDPGEELEDPKEQSVITNHTGNNTKEEDTTASQVSALPLILPVGTTRSRSISSRS 469

  Fly   375 SF------------DPNKKH----------LEKIFKKQSKLKQNDLQLDIDEKHF-----LQNSQ 412
            |.            .|..:|          |::...|.|.:.|.:.|..::...|     ||..|
  Fly   470 STVSSASQPHLVIDHPESEHNAKPPALKLSLKRRRSKSSSVSQPEKQTKVEAGGFVSSLLLQRLQ 534

  Fly   413 TTSGLAIKANSNE----------------------NALQADIPSQPPTVTSQI----ENNFR--- 448
            :.|.:...|.|.|                      |..||.........:||:    |..||
  Fly   535 SNSNVIPPAISTESQQVLSCAKCNLQFDFERFQELNKHQAQCSGIQSANSSQLSQKQERFFRCSQ 599

  Fly   449 --------------------------NSIYP---------------------------------- 453
                                      |.:||
  Fly   600 CCSVHQCWHFFLHMREVHRRYICLYCNHVYPSVEKLSLHLENKHDIDQSHFAKDAWDQQQSKEDR 664

  Fly   454 ---------------------------VQPSVI--QQTQVLLAEKKSGSEPERSKLDIFKKISKP 489
                                       :||..:  |:...::..|.:..:|.:.:    :|:.:|
  Fly   665 ARHLVCCTCQATFVQGSEFEDHDCSQLMQPCALCNQKGGHIIGCKNNKRKPTKRR----RKVRRP 725

  Fly   490 RTPRPDIGATLVPPGTGVSVFGSTMT-------------PSALISLPSGTTITPTPSLGLNSENK 541
            ..|...:....|.....|......:.             |:..|..|......|.|.:    ...
  Fly   726 PEPPLPVSQEAVEQPVPVEAIPEQLPQQLHLQSDIQNPFPAENIPAPEPVEDPPAPPI----PKL 786

  Fly   542 NVPSMKINPCNIFDGTIPL-------------TKAGVEMSI--------IDSPKPKKRGRKPGGK 585
            .||.:.:.....|..::..             |...||.::        .|:|.|..........
  Fly   787 VVPKIMLRVPKEFQKSVDAALSSTDTEDEELETAQPVEEAVSAPPEDLPFDAPPPPPPALSYDDS 851

  Fly   586 NVIKQTNVVSQPLINK--VERKKSS---------------------QAITLPLSSSPMIITQSSL 627
            ...|...|:::....|  :||.|:.                     |.:..|....|....|...
  Fly   852 TSSKLNRVLAELERTKLDIERTKADIITKKQSKIIMANAHLENVVPQVVDPPQHLQPQQEEQRRW 916

  Fly   628 NVSPPTEP-LNLCNTEQPSNNFLSNLYAKEKKDRKKYKSLPENVMQLDKSC-SPEK------AST 684
            :::||..| .|..|..:|....::..  :.:.|..:..||..:.|.:|.|. :||.      ...
  Fly   917 SLTPPASPHNNHVNLPEPPPALITEF--QGQPDAVRRNSLGSDCMDMDDSLNAPEMEGSRDFTEA 979

  Fly   685 LHNSIRPTKQNNDVQCSDKFVTISNALSNASIYPGIQTGMVPLLPLLQFPPRPGLIPTGPG---- 745
            ...::.|...:.|.|.:|:.:.|.                    ||   ||..|::..||.
  Fly   980 QKETLEPAPPSQDTQTADEPLAIQ--------------------PL---PPADGIMVAGPDTHTV 1021

  Fly   746 -------------------LFPAVTGLVGFGNHGNRIPI---------------SPFIDYPGPEE 776
                               ...:|..|..:.||..||.:               :..:|....||
  Fly  1022 DLQLDRPLDRFSMVDFVRLCLKSVYSLCLYCNHARRIAVNVKQLVIHLIGQHRFTATVDSITAEE 1086

  Fly   777 SVADTVRCPPIKDSPVTDSDQFLSRSSTQTDLQMDRNYCNVAPLVPDSMKFAECKSVSCASTILE 841
            ..|:|:         |.....||.        .::..|.|.|               ||.|  ||
  Fly  1087 LYAETI---------VAKLKSFLP--------NLENEYMNAA---------------SCCS--LE 1117

  Fly   842 NPSAQATSKINTKPLLEASGNPDDPIE------------VSDDSDESMHNRQM--------VQRK 886
            |                  |...:|..            .|...:...|||::        |..:
  Fly  1118 N------------------GKYVEPFNERIYECFTCRFVTSTHKELYTHNRRLHIKSNITCVMCQ 1164

  Fly   887 TPISS---------PTYVKTSFAELN-----------PSSFTSAASNGEEKSKMDL-----RNIV 926
            |...|         |..|..|..:|.           ||:|.......::....|:     ::..
  Fly  1165 TNFYSYSEILCHICPGEVAGSVYDLQFRCCLCDMAPLPSAFRLMVHLRKQHQACDICLEDCQSQS 1229

  Fly   927 SLSSNEPLKKFKKLV---------KQSFPDVKSVPHTPAS---------------HSSFPQFNLP 967
            .|||:....|...|.         ||.........|...|               |...|....|
  Fly  1230 KLSSHVWKHKLLHLCYRCGIAYRNKQDISKHLFWKHGTESAGCKQCLQKRWRHVYHFCVPPAEFP 1294

  Fly   968 NFMGGDKFSLAGGADLIPLSRVSDSEY------------SSKIV---PFSSLGGTIPNQIKISEE 1017
            ....|..||.|...::.......|..|            |.|::   ..|.:...:|..:.:.:.
  Fly  1295 CEQCGFVFSKAIYLEVHQRMHTGDFRYACTEEGCEEKFVSRKLLLKHASSHVAKELPQAVSVEQT 1359

  Fly  1018 HNIFSTFSNYEDITITPTGLTSLEPKMRKHHKKLKKVKEGKNKKKKEKKDKSKKAD-QIGLPSFK 1081
            .:...| ...|||   ...|...|.:....|.:.|.:.|.....:..||::|.:.| .|..|..|
  Fly  1360 ADAAPT-EKLEDI---KEELEEGEDEKEGAHNQEKLLSESLTNNETPKKEESDRIDNSIEPPLSK 1420

  Fly  1082 SDRKIKANDKRQKKEKKKDKDKQILVHIPDDTEEFDKVPLANNDEPVLKSSSMTINPSLGAATSG 1146
            |:     |.||:||.|:..:..:.|..|..:..|.|....:::|.|   .||....|.| ...|.
  Fly  1421 SE-----NRKRRKKSKRNKESLEDLNLIAPNLSESDSSDDSDSDAP---RSSHQEQPKL-PMRSS 1476

  Fly  1147 ISPNQIPKLTL---------KLSGKSTLFSSSEKEMTDAGKLK---------------------- 1180
            :....:||:.|         :|.|||.|....||.:..:.:.|
  Fly  1477 VDDLDMPKVMLSPSSESDADELDGKSKLEDKEEKPLDGSTEEKALDADDELEPKKEEDQVDVSIW 1541

  Fly  1181 ------QTTILSSEN--KKRERDNSPELARFSPLVTGPPKNKQSETLHLGNSSTAV-----LPVP 1232
                  |...:..|.  |..||::|        ||..||..     ||:..|....     .|.|
  Fly  1542 KNLLQNQAVAIPEEQAVKDEEREDS--------LVNLPPAK-----LHVAWSDHDYCKLYRTPAP 1593

  Fly  1233 SPVAVRAVQLPVSQTSSNSAGWLSNPNNSNTASSTLSASSVLLPQQLMLAPHTIMNNFVPAMCNS 1297
            |||..::......:|...:|.  |:.::|:::||:.|.||                   ...|.|
  Fly  1594 SPVKQKSANKSSIKTPGENAS--SDSDSSSSSSSSDSDSS-------------------SCSCGS 1637

  Fly  1298 TGTVSKSGLCSSPPNTSEENAN-------------AMQIAESSRPSSYVDAEGNRIWICPACGKV 1349
            ..:.|.|...||..|:.:.:::             ::::.:||. |..:|..|..     ...:|
  Fly  1638 NCSCSSSNSSSSSGNSDDSDSSTARGSPQKRSRKKSLKVKKSSE-SLKIDQNGQN-----EQNQV 1696

  Fly  1350 DDGSAM 1355
            :|.:|:
  Fly  1697 EDTTAV 1702

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bip2	NP_651923.2	BTP	4..80	CDD:128846	12/58 (21%)
		PHD_TAF3	1342..1387	CDD:276997	3/14 (21%)
MESR4	NP_001097359.1	C2H2 Zn finger	1272..1288	CDD:275368	1/15 (7%)
		C2H2 Zn finger	1295..1315	CDD:275370	4/19 (21%)
		C2H2 Zn finger	1323..1341	CDD:275370	2/17 (12%)
		PHD_ING	2110..2156	CDD:276980

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5034
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900