DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bip2 and Ing3

DIOPT Version :9

Sequence 1:	NP_651923.2	Gene:	bip2 / 43793	FlyBaseID:	FBgn0026262	Length:	1406	Species:	Drosophila melanogaster
Sequence 2:	NP_573316.1	Gene:	Ing3 / 32853	FlyBaseID:	FBgn0030945	Length:	686	Species:	Drosophila melanogaster

Alignment Length:	215	Identity:	58/215 - (26%)
Similarity:	85/215 - (39%)	Gaps:	55/215 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly  1212 KNKQSETLHLGNSSTAVLPVPSPVAVRAVQLPVSQTSSNSAGWLSNPN----NSNTASSTLSASS 1272
            :.||.:.|      |..|.:|:      ||.....:|.||.|..|:.:    |..|.|:.|:|:|
  Fly   498 EKKQKKKL------TTALTLPT------VQPTAGSSSGNSIGSSSSISLESVNKLTTSAALAAAS 550

  Fly  1273 VLLPQQLMLAPHTIMNNFVPAMCNST------GTVSKSGLCSSP--------PNTSEENANAMQI 1323
                     |..|.|:....|:...|      |.:::|.....|        |.|:....:::.|
  Fly   551 ---------ATTTYMSVGGQALLAMTPGGGGGGNLAESSAEGVPAGMIAMNLPTTTVTPGSSLTI 606

  Fly  1324 AESSRPSSYVDAEG------NRIWICPACGKVDDGSAMIGCDGCDA----WYHWICVGITFAPKD 1378
            .|:.......: ||      |....| .|.:|..|. |:.||. ||    |:|:.|||||..||.
  Fly   607 GENGLVVEQTN-EGEWSYDPNEPRYC-TCNQVSYGD-MVACDN-DACPYEWFHYPCVGITQPPKG 667

  Fly  1379 NDDWFCRVCVTKKRIHGSEK 1398
            .  |:|..|....|..|:.|
  Fly   668 K--WYCPKCTASMRRRGNRK 685

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bip2	NP_651923.2	BTP	4..80	CDD:128846
bip2	NP_651923.2	PHD_TAF3	1342..1387	CDD:276997	20/48 (42%)
Ing3	NP_573316.1	ING	3..103	CDD:289749
Ing3	NP_573316.1	PHD_ING3	630..674	CDD:277060	20/48 (42%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5034
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.900