DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bip2 and phf-34

DIOPT Version :9

Sequence 1:	NP_651923.2	Gene:	bip2 / 43793	FlyBaseID:	FBgn0026262	Length:	1406	Species:	Drosophila melanogaster
Sequence 2:	NP_509661.1	Gene:	phf-34 / 184793	WormBaseID:	WBGene00009025	Length:	246	Species:	Caenorhabditis elegans

Alignment Length:	232	Identity:	57/232 - (24%)
Similarity:	82/232 - (35%)	Gaps:	57/232 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly  1206 LVTGP-----------PKNKQSETLHLGNSSTAVLPVPSPVAVRAVQLPVS------QTSSNSAG 1253
            |.|||           .:..:...|:||    .:|..|.|..:||.:..:.      ..|..:|.
Worm    21 LCTGPVTVLEQALEQLERYPERGHLYLG----PILFGPEPYKLRACKTCIRLARHGLSASRFTAE 81

  Fly  1254 WLSN-----PNN-----SNTASSTLSASSVLLPQQL--MLAPH--TIMNNFVPAMCNST--GTVS 1302
            .:.|     |.:     |...:...:|....|.:||  |.|.|  .|....:.....||  ..|.
Worm    82 EIENMTELCPTHLDEQLSEERAKAKAALEAKLAKQLKQMQAKHRKEIKEAEMAKTIRSTKKTKVG 146

  Fly  1303 KSGLCSSPPNTSEENANAMQIAESSRPSSYVDAEG----------------NRIWICPACGKVDD 1351
            |:|..:.....:.:.....|:.:..:|...::.|.                .| ||||.|.|...
Worm   147 KNGKIAKVDKKTAKTVKEKQVLDLPQPKIEINDEDIDQYILEQAAPKKKNVTR-WICPTCDKSSK 210

  Fly  1352 -GSAMIGCDGCDAWYHWICVGITFAPKDNDDWFCRVC 1387
             ||.  ||.||..|||..|||...|.:..|.|.|:.|
Worm   211 FGSC--GCVGCGDWYHITCVGFKKAKEVPDKWACKYC 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bip2	NP_651923.2	BTP	4..80	CDD:128846
bip2	NP_651923.2	PHD_TAF3	1342..1387	CDD:276997	21/45 (47%)
phf-34	NP_509661.1	PHD	201..245	CDD:214584	21/45 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S5668
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.850