DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bip2 and lsy-13

DIOPT Version :9

Sequence 1:	NP_651923.2	Gene:	bip2 / 43793	FlyBaseID:	FBgn0026262	Length:	1406	Species:	Drosophila melanogaster
Sequence 2:	NP_001367153.1	Gene:	lsy-13 / 178470	WormBaseID:	WBGene00020287	Length:	247	Species:	Caenorhabditis elegans

Alignment Length:	265	Identity:	49/265 - (18%)
Similarity:	94/265 - (35%)	Gaps:	53/265 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly  1165 LFSSSEKEMTDAGK-----LKQTTILSSENKKRERDNSPELARFSPLVTGPPKNK-----QSETL 1219
            :||...:|:.:..|     :::..||:.:..:..:.:..|.......:|...|.|     |.:..
Worm    13 VFSKINREVPEKAKKAIVEIERLDILAKKEMEVAKKHKIEFFANYEEMTAEQKTKAFTFMQKKMA 77

  Fly  1220 HLGNSSTAVLPVPSPVAVRAVQLPVSQTSSNSAGWLSNPNNSNTASSTLSASSVLLPQQLMLAPH 1284
            .:...|...:.:.|.:.|....: ..:.......::.|.|....|..|..:||
Worm    78 KVSEYSDQKIEIASGLKVLLKDV-YGKFMEEEQKFIENLNKIPKAPETPPSSS------------ 129

  Fly  1285 TIMNNFVPAMCNSTGTVSKSGLCSSPPNTSEENANAMQIAESSRPSSYVDAEGNRIWICPACGKV 1349
                   |::.:........|...:|.:..|:.....:..||.:..:..:......|    | ::
Worm   130 -------PSVRSHRKKKLSEGDDDAPSSVDEKKRGRKKKPESEKAVAAAEPPKMYCW----C-QL 182

  Fly  1350 DDGSAMIGCD--GCD-AWYHWICVGITFAPKDNDDWFCRVCVTKKRIHG----------SEKKKR 1401
            |....||.|:  ||. .|:|:.|:|:..||.  .||:   |..:.|..|          :.::|.
Worm   183 DKNDTMIECENPGCKYGWFHFTCIGMITAPA--GDWY---CTNECRAQGLAAVAEAPQKAPQRKG 242

  Fly  1402 RNKKK 1406
            ..|||
Worm   243 LKKKK 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bip2	NP_651923.2	BTP	4..80	CDD:128846
bip2	NP_651923.2	PHD_TAF3	1342..1387	CDD:276997	15/47 (32%)
lsy-13	NP_001367153.1	PHD_SF	177..222	CDD:419867	17/54 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5034
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900