DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bip2 and taf-8

DIOPT Version :9

Sequence 1:	NP_651923.2	Gene:	bip2 / 43793	FlyBaseID:	FBgn0026262	Length:	1406	Species:	Drosophila melanogaster
Sequence 2:	NP_001022514.1	Gene:	taf-8 / 174524	WormBaseID:	WBGene00006390	Length:	497	Species:	Caenorhabditis elegans

Alignment Length:	324	Identity:	63/324 - (19%)
Similarity:	120/324 - (37%)	Gaps:	95/324 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   888 PISSP-TYVKTSFAELNPSSFTSAASNGEEKSKMDLRNIVS-LSSNEP----LKKFKKL----VK 942
            |:..| ||:||..:|....|:........:|.:..:.::|: :..|.|    .:.|:::    ||
Worm   190 PLPDPHTYIKTEISEDIDFSYEKVREAMSQKKRNGITSLVNYMIRNYPSICLFRNFEEIIHEQVK 254

  Fly   943 QSF---PDVKSVPHTPASHSSFPQFNLPNFMGGDKFSLAGGADLIPLSRVSDSEYSSKIVPFSSL 1004
            ::|   .:.|.:.....:.....|.|                |:..:..||.|.|...::....|
Worm   255 KTFNKESEEKRMQEAFVAFRDLVQTN----------------DIDEVKNVSKSLYDKGLISKHEL 303

  Fly  1005 -GGTIPNQIKISEEHNIFSTFSNYEDITITPTGLTSLEPKMR------------------KHHKK 1050
             .||  ..:.:|.:..:...|.  |.:.::.|....||.|.|                  ::|..
Worm   304 QSGT--EVLCMSSDGALIDQFG--ERVYLSETTSIDLEDKDRVSKSSTRMTTCGDGAESLRYHWP 364

  Fly  1051 L-------------------KKVKEGKNKKKKEKKDKSKKADQIGLPSF--KSDRKIKANDKRQK 1094
            :                   :|:.|.|..::|...:...:...|.:|||  ::...:.::|.:.:
Worm   365 IDEMLDELIELDSCTMDLGDEKIDEMKYMQEKTTFEYLPEWCHILIPSFEHRAYLTVVSDDLKAE 429

  Fly  1095 KEKKKDKDKQILVHIPDDTEEFDK----------------VPLANN------DEPVLKSSSMTI 1136
            :|.||||||:....|.|.|||..|                .|:.:|      ||.:.:.|::.:
Worm   430 EESKKDKDKEKDKQIGDLTEEEKKGKDEEIFQTHENLYLCPPIRDNDYGNYEDEEITEESALEV 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bip2	NP_651923.2	BTP	4..80	CDD:128846
bip2	NP_651923.2	PHD_TAF3	1342..1387	CDD:276997
taf-8	NP_001022514.1	BTP	66..142	CDD:128846
taf-8	NP_001022514.1	TAF8	182..235	CDD:176263	10/44 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1475
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.940