DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bip2 and TAF8

DIOPT Version :9

Sequence 1:	NP_651923.2	Gene:	bip2 / 43793	FlyBaseID:	FBgn0026262	Length:	1406	Species:	Drosophila melanogaster
Sequence 2:	XP_011512598.1	Gene:	TAF8 / 129685	HGNCID:	17300	Length:	338	Species:	Homo sapiens

Alignment Length:	195	Identity:	43/195 - (22%)
Similarity:	75/195 - (38%)	Gaps:	37/195 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 VVVAQITQTIGYSCTLSAPLELLQDILQKFVQEFARDMHRHMEHANRIEPNLKDARLSIKNLSIN 77
            |||:.:....|:.....|.:|.|.::||.::.|..|....:.||..|.:|.|.|..:::..:..|
Human    39 VVVSSLLTEAGFESAEKASVETLTEMLQSYISEIGRSAKSYCEHTARTQPTLSDIVVTLVEMGFN 103

  Fly    78 VQELLDY-------IGNVEPVGFIRDVPQFPIGKSVNMNFLKPGSAETLTRPVYIFEYLPPMQDP 135
            |..|..|       :....||   .:.|..|...:...|  :|       .|.:|..:.|...||
Human   104 VDTLPAYAKRSQRMVITAPPV---TNQPVTPKALTAGQN--RP-------HPPHIPSHFPEFPDP 156

  Fly   136 E-------LREIPADVQ----KEFSEKQE-------FCSKAEYSSTNAADKLGAKHIDSISPNTV 182
            .       .||..:|.|    |..|::::       |.:|...:.:...|.:....:.:..|.|:
Human   157 HTYIKTPTYREPVSDYQVLREKAASQRRDVERALTRFMAKTGETQSLFKDDVSTFPLIAARPFTI 221

Fly 183 182
Human 222 221

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bip2	NP_651923.2	BTP	4..80	CDD:128846	19/66 (29%)
bip2	NP_651923.2	PHD_TAF3	1342..1387	CDD:276997
TAF8	XP_011512598.1	Bromo_TP	29..106	CDD:284856	19/66 (29%)
		TAF8	144..197	CDD:176263	11/52 (21%)
		GVQW	266..>303	CDD:290611
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2389
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1475
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840