DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKI and Dcx

DIOPT Version :9

Sequence 1:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	XP_006257444.1	Gene:	Dcx / 84394	RGDID:	620670	Length:	366	Species:	Rattus norvegicus

Alignment Length:	253	Identity:	52/253 - (20%)
Similarity:	84/253 - (33%)	Gaps:	83/253 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 LNKQVSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLENEIRVLRRF 85
            :|....:...|.:.|....|:..|:...||.....::|..|:          |..:|   |...:
  Rat    95 INLPQGVRYIYTIDGSRKIGSMDELEEGESYVCSSDNFFKKV----------EYTKN---VNPNW 146

  Fly    86 SANHFDGKCLNGTR-LTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKG--------SYT 141
            |.|......:...: |...|..|..|     :|.::..:|||       |:..|        ...
  Rat   147 SVNVKTSANMKAPQSLASSNSAQARE-----NKDFVRPKLVT-------IIRSGVKPRKAVRVLL 199

  Fly   142 EKDASHLIRQIL----EAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSGIMA 202
            .|..:|...|:|    ||:..  |.|||.:        .|:.|......:.||    ..|..:.
  Rat   200 NKKTAHSFEQVLTDITEAIKL--ETGVVKK--------LYTLDGKQVTCLHDF----FGDDDVF- 249

  Fly   203 TACGTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGD 260
            .|||      ||     .:..|.|.:|:               |||:    .:::||:
  Rat   250 IACG------PE-----KFRYAQDDFSL---------------DENE----CRVMKGN 277

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	51/247 (21%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	51/243 (21%)
Dcx	XP_006257444.1	DCX1_DCX	51..139	CDD:340529	10/53 (19%)
		DCX2	176..259	CDD:340589	25/115 (22%)
		KLF8_12_N	<284..>343	CDD:424081
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920