DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKI and CPK19

DIOPT Version :9

Sequence 1:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_176386.2	Gene:	CPK19 / 842490	AraportID:	AT1G61950	Length:	551	Species:	Arabidopsis thaliana

Alignment Length:	341	Identity:	138/341 - (40%)
Similarity:	211/341 - (61%)	Gaps:	24/341 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 IEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVK-IIDKKALKGKE-ESLENEIRVLRRFSANH 89
            |:|||:|...||.|.|....:. ::.|.|::||.| |:.:|.::.|: |.:..||:::      |
plant    94 IKEKYSLGRELGRGQFGITYIC-TEISSGKNFACKSILKRKLIRTKDREDVRREIQIM------H 151

  Fly    90 FDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIRQILE 154
            :    |:|    .||||::...|||:..|:|||||..||||||:|.::|.|:||.|:.:||.:::
plant   152 Y----LSG----QPNIVEIKGAYEDRQSVHLVMELCEGGELFDKITKRGHYSEKAAAEIIRSVVK 208

  Fly   155 AVDYMHEQGVVHRDLKPENLLYYSPDDDSKIM-ISDFGLSK-MEDSGIMATACGTPGYVAPEVLA 217
            .|...|..||:||||||||.|..|.|:.|.:: .:|||:|. :|:..:.....|:..|||||||
plant   209 VVQICHFMGVIHRDLKPENFLLSSKDEASSMLKATDFGVSVFIEEGKVYEDIVGSAYYVAPEVL- 272

  Fly   218 QKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKHFIKNL 282
            ::.||||:|:||.|||.||||||.|||:.|.|..:|.:||:|:.:|:|..|..||||||..::|:
plant   273 KRNYGKAIDIWSAGVILYILLCGNPPFWAETDKGIFEEILRGEIDFESEPWPSISESAKDLVRNM 337

  Fly   283 MCVTVEKRYTCKQALGHAWI-SGNEASSRNIHGTVSEQLKKNFAKSRWKQ-AY-YAATVIRQMQR 344
            :....:||:|..|.|.|.|| .|.|||.:.|...|..::|:..|.::.|: |: :.|..:::.:.
plant   338 LKYDPKKRFTAAQVLEHPWIREGGEASDKPIDSAVLSRMKQLRAMNKLKKLAFKFIAQNLKEEEL 402

  Fly   345 MALNSNSNANFDSSNS 360
            ..|.: ..||.|:..|
plant   403 KGLKT-MFANMDTDKS 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	120/277 (43%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	117/274 (43%)
CPK19	NP_176386.2	STKc_CAMK	97..356	CDD:270687	118/274 (43%)
		Pkinase	98..357	CDD:278497	117/274 (43%)
		PTZ00184	393..538	CDD:185504	6/26 (23%)
		EFh	405..464	CDD:238008	5/14 (36%)
		EFh	477..537	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I1119
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm971
orthoMCL	1	0.900	-	-		OOG6_100153
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.770