DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKI and CPK26

DIOPT Version :9

Sequence 1:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_001190949.1	Gene:	CPK26 / 829980	AraportID:	AT4G38230	Length:	514	Species:	Arabidopsis thaliana

Alignment Length:	386	Identity:	143/386 - (37%)
Similarity:	204/386 - (52%)	Gaps:	33/386 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 KQVSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKE--ESLENEIRVLRRF 85
            |..||.:.|:|...||.|.|....:.: :.|.|..:|.|.|.|:.|..||  |.:..||:::
plant    46 KTPSIRDLYSLGHKLGQGQFGTTYMCK-EISTGREYACKSITKRKLISKEDVEDVRREIQIM--- 106

  Fly    86 SANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIR 150
              :|..|         :.|||.:...|||...|::||||.:||||||||:::|.|:|:.|:.||:
plant   107 --HHLAG---------YKNIVTIKGAYEDPLYVHIVMELCSGGELFDRIIQRGHYSERKAAELIK 160

  Fly   151 QILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSG-IMATACGTPGYVAPE 214
            .|:..|:..|..||:||||||||.|..:.|||..:...|||||.....| |.....|:|.|||||
plant   161 IIVGVVEACHSLGVMHRDLKPENFLLVNKDDDFSLKAIDFGLSVFFKPGQIFEDVVGSPYYVAPE 225

  Fly   215 VLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKHFI 279
            ||. |.||...|||:.|||.|||:.|.|||:.|....:|..:|||..:|||..|..||:|||:.|
plant   226 VLL-KHYGPEADVWTAGVILYILVSGVPPFWAETQQGIFDAVLKGHIDFDSDPWPLISDSAKNLI 289

  Fly   280 KNLMCVTVEKRYTCKQALGHAWISGN-EASSRNIHGTVSEQLKKNFAKSRWKQAYYAATVIRQMQ 343
            :.::|....:|.|..|.|.|.||..| .|..|.:...|..:||:..|.::.||  .|..||.:
plant   290 RGMLCSRPSERLTAHQVLRHPWICENGVAPDRALDPAVLSRLKQFSAMNKLKQ--MALRVIAE-- 350

  Fly   344 RMALNSNSNAN----FDSSNSSNQDSTT---PTAATGAWTSNVLSSQQSVQSHAQEMNKSG 397
              :|:....|.    |.:.::.|..:.|   ..|....:.|.:..::......|.:::|||
plant   351 --SLSEEEIAGLKEMFKAMDTDNSGAITFDELKAGLRRYGSTLKDTEIRDLMEAADIDKSG 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	116/276 (42%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	115/273 (42%)
CPK26	NP_001190949.1	Pkinase	54..312	CDD:278497	115/273 (42%)
		STKc_CAMK	54..311	CDD:270687	115/272 (42%)
		PTZ00184	348..490	CDD:185504	12/66 (18%)
		EFh	360..419	CDD:238008	9/50 (18%)
		EFh	431..491	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I1119
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm971
orthoMCL	1	0.900	-	-		OOG6_100153
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.770