DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKI and CPK18

DIOPT Version :9

Sequence 1:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_001190932.1	Gene:	CPK18 / 829763	AraportID:	AT4G36070	Length:	561	Species:	Arabidopsis thaliana

Alignment Length:	335	Identity:	126/335 - (37%)
Similarity:	182/335 - (54%)	Gaps:	35/335 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 FGKK-DSGKKAKAKDLKELNKQVSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKA 67
            :||: |.|   .|||         .:.:|.:..|||.|.|....:|...:: |...|||.|||..
plant    55 YGKRIDFG---YAKD---------FDNRYTIGKLLGHGQFGFTYVATDNNN-GNRVAVKRIDKAK 106

  Fly    68 LKG--KEESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGEL 130
            :..  :.|.::.|:::|          :.|.|    |.|:|.....:|||:.:|:||||..||||
plant   107 MTQPIEVEDVKREVKIL----------QALGG----HENVVGFHNAFEDKTYIYIVMELCDGGEL 157

  Fly   131 FDRIVEK--GSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLS 193
            .|||:.|  ..||||||:.::||:|:.....|.:|:||||:||||.|:.|.::.|.:..:|||||
plant   158 LDRILAKKDSRYTEKDAAVVVRQMLKVAAECHLRGLVHRDMKPENFLFKSTEEGSSLKATDFGLS 222

  Fly   194 KMEDSGI-MATACGTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQIL 257
            .....|: .....|:..|||||||.::. |...||||||||:||||||..||:|:....:|.:::
plant   223 DFIKPGVKFQDIVGSAYYVAPEVLKRRS-GPESDVWSIGVITYILLCGRRPFWDKTQDGIFNEVM 286

  Fly   258 KGDFEFDSPYWDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWI-SGNEASSRNIHGTVSEQLK 321
            :...:|....|..||..||.|:|.|:......|.|..|||.|:|: .|.|||...|..:|...::
plant   287 RKKPDFREVPWPTISNGAKDFVKKLLVKEPRARLTAAQALSHSWVKEGGEASEVPIDISVLNNMR 351

  Fly   322 KNFAKSRWKQ 331
            :....||.||
plant   352 QFVKFSRLKQ 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	108/278 (39%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	108/275 (39%)
CPK18	NP_001190932.1	STKc_CAMK	70..330	CDD:270687	108/275 (39%)
		S_TKc	71..331	CDD:214567	108/275 (39%)
		PTZ00184	367..514	CDD:185504
		EFh	378..437	CDD:238008
		EFh	459..513	CDD:238008
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I1119
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm971
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.960