DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKI and CPK23

DIOPT Version :9

Sequence 1:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_001190672.1	Gene:	CPK23 / 825809	AraportID:	AT4G04740	Length:	533	Species:	Arabidopsis thaliana

Alignment Length:	378	Identity:	134/378 - (35%)
Similarity:	205/378 - (54%)	Gaps:	22/378 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 IEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGK--EESLENEIRVLRRFSANH 89
            |.:.|:|...||.|......:.: :...|..:|.|.|.|:.|..:  .|.::.||::::     |
plant    65 IRKFYSLGRELGRGGLGITYMCK-EIGTGNIYACKSILKRKLISELGREDVKTEIQIMQ-----H 123

  Fly    90 FDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIRQILE 154
            ..|:         ||:|::..:|||:..|:|||||..||||||||:.:|.|:|:.|:..|:.|::
plant   124 LSGQ---------PNVVEIKGSYEDRHSVHLVMELCAGGELFDRIIAQGHYSERAAAGTIKSIVD 179

  Fly   155 AVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSK-MEDSGIMATACGTPGYVAPEVLAQ 218
            .|...|..||:||||||||.|:.|.::::.:.::|||||. :|:..|.....|:|.|||||||.|
plant   180 VVQICHLNGVIHRDLKPENFLFSSKEENAMLKVTDFGLSAFIEEGKIYKDVVGSPYYVAPEVLRQ 244

  Fly   219 KPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKHFIKNLM 283
            . |||.:|:||.|||.||||||.|||:.:|:..:|.:|||...:|....|..||:|||..::.::
plant   245 S-YGKEIDIWSAGVILYILLCGVPPFWADNEEGVFVEILKCKIDFVREPWPSISDSAKDLVEKML 308

  Fly   284 CVTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLKKNFAKSRWKQ-AYYAATVIRQMQRMAL 347
            ....::|.|..|.|.|.||.|.||..:.|..||..::|:..|.::.|: |...:.|....:.:..
plant   309 TEDPKRRITAAQVLEHPWIKGGEAPEKPIDSTVLSRMKQFRAMNKLKKLALKVSAVSLSEEEIKG 373

  Fly   348 NSNSNANFDSSNSSNQDSTTPTAATGAWTSNVLSSQQSVQSHAQEMNKSGGST 400
            .....||.|::.|..  .|.....||........|:..||...:..:..|..|
plant   374 LKTLFANMDTNRSGT--ITYEQLQTGLSRLRSRLSETEVQQLVEASDVDGNGT 424

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	109/276 (39%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	108/273 (40%)
CPK23	NP_001190672.1	STKc_CAMK	82..326	CDD:270687	103/259 (40%)
		S_TKc	84..327	CDD:214567	103/258 (40%)
		EF-hand_7	374..433	CDD:290234	12/53 (23%)
		EFh	374..433	CDD:238008	12/53 (23%)
		EFh	445..>492	CDD:238008
		EF-hand_7	446..>492	CDD:290234
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I1119
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm971
orthoMCL	1	0.900	-	-		OOG6_100153
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.770