DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKI and CPK13

DIOPT Version :9

Sequence 1:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_190753.2	Gene:	CPK13 / 824348	AraportID:	AT3G51850	Length:	528	Species:	Arabidopsis thaliana

Alignment Length:	349	Identity:	130/349 - (37%)
Similarity:	193/349 - (55%)	Gaps:	37/349 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 KKDS--GKK-AKAKDLKELNKQVSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKA 67
            :||:  ||| |..:.|.::.|: :||::|.|...||.|.|....|...:.| .:..|.|.|.|:.
plant    27 RKDAAGGKKSAPIRVLSDVPKE-NIEDRYLLDRELGRGEFGVTYLCIERSS-RDLLACKSISKRK 89

  Fly    68 LKGKE--ESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGEL 130
            |:...  |.::.|:.:::....:              .:||.|.|..||.:.|:|||||..||||
plant    90 LRTAVDIEDVKREVAIMKHLPKS--------------SSIVTLKEACEDDNAVHLVMELCEGGEL 140

  Fly   131 FDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKM 195
            |||||.:|.|||:.|:.:.:.|:|.|...|:.||:||||||||.|:.:..::|.:...|||||..
plant   141 FDRIVARGHYTERAAAGVTKTIVEVVQLCHKHGVIHRDLKPENFLFANKKENSPLKAIDFGLSIF 205

  Fly   196 EDSG-IMATACGTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKG 259
            ...| ..:...|:|.|:||||| ::.||..:|:||.|||.||||||.|||:.|::..:...||:|
plant   206 FKPGEKFSEIVGSPYYMAPEVL-KRNYGPEIDIWSAGVILYILLCGVPPFWAESEQGVAQAILRG 269

  Fly   260 DFEFDSPYWDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWISGNEASSRNIH-GTVSEQLKKN 323
            ..:|....|..|||:||:.::.::....::|.|.||.|.|.||. |...:.|:. |.|
plant   270 VIDFKREPWPNISETAKNLVRQMLEPDPKRRLTAKQVLEHPWIQ-NAKKAPNVPLGDV------- 326

  Fly   324 FAKSRWKQAYYAATVIRQMQRMAL 347
             .|||.||    .:|:.:.:|.||
plant   327 -VKSRLKQ----FSVMNRFKRKAL 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	107/276 (39%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	105/273 (38%)
CPK13	NP_190753.2	STKc_CAMK	53..311	CDD:270687	105/273 (38%)
		FRQ1	352..493	CDD:227455
		EFh_PEF	470..>526	CDD:355382
		EF-hand motif	470..497	CDD:320054
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I1119
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm971
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.870