DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKI and CPK25

DIOPT Version :9

Sequence 1:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_001318361.1	Gene:	CPK25 / 818162	AraportID:	AT2G35890	Length:	520	Species:	Arabidopsis thaliana

Alignment Length:	356	Identity:	131/356 - (36%)
Similarity:	190/356 - (53%)	Gaps:	47/356 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 SGKKAKAKDLKEL------------NKQVSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVK 61
            :..|.||.:::.|            .|...::|.|||...||.|.|....:...|.: ||.:|.|
plant    98 ANSKRKAHNVRRLMSAGLQAESVLKTKTGHLKEYYNLGSKLGHGQFGTTFVCVEKGT-GEEYACK 161

  Fly    62 IIDKKALKGKE--ESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMEL 124
            .|.|:.|:.:|  |.:..||.:::..              |..||::.:...|||...|::||||
plant   162 SIPKRKLENEEDVEDVRREIEIMKHL--------------LGQPNVISIKGAYEDSVAVHMVMEL 212

  Fly   125 VTGGELFDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISD 189
            ..||||||||||:|.|:|:.|:||.:.||..|...|..||:||||||||.|:.:.|:||.:...|
plant   213 CRGGELFDRIVERGHYSERKAAHLAKVILGVVQTCHSLGVMHRDLKPENFLFVNDDEDSPLKAID 277

  Fly   190 FGLSKMEDSGIMAT-ACGTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLF 253
            ||||.....|...| ..|:|.|:||||| .|.||...|:||.||:.|:||.|..||:.|.:..:|
plant   278 FGLSMFLKPGENFTDVVGSPYYIAPEVL-NKNYGPEADIWSAGVMIYVLLSGSAPFWGETEEEIF 341

  Fly   254 AQILKGDFEFDSPYWDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWI--SGNEASSRNIHGTV 316
            .::|:|:.:..|..|.::|||||..|:.::.....:|.|.:|.|.|.||  .|| |....:..||
plant   342 NEVLEGELDLTSDPWPQVSESAKDLIRKMLERNPIQRLTAQQVLCHPWIRDEGN-APDTPLDTTV 405

  Fly   317 SEQLKKNFAKSRWKQAYYAATVIRQMQRMAL 347
            ..:|||           ::||  .::::|||
plant   406 LSRLKK-----------FSAT--DKLKKMAL 423

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	111/276 (40%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	110/273 (40%)
CPK25	NP_001318361.1	STKc_CAMK	132..389	CDD:270687	110/272 (40%)
CPK25	NP_001318361.1	FRQ1	429..>509	CDD:227455
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	234	1.000	Inparanoid score	I1119
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm971
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X46
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.870