DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKI and uhmk1

DIOPT Version :9

Sequence 1:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	NP_001070127.1	Gene:	uhmk1 / 767721	ZFINID:	ZDB-GENE-060929-1014	Length:	410	Species:	Danio rerio

Alignment Length:	232	Identity:	64/232 - (27%)
Similarity:	100/232 - (43%)	Gaps:	62/232 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 YNLHGLLGTGAFSEV-RLAESKDSPGEHFAVK--IIDKKALKGKEESLENEIRVLRRFSANHFDG 92
            :|:...||.|..:.| |::..:.:.    |||  .:|.   :|.:.....|..||.:...
Zfish    24 WNVQARLGQGVSASVYRVSSGRATS----AVKEFQVDP---QGGDYGYLKESSVLEKIQG----- 76

  Fly    93 KCLNGTRLTHPNIVQLLETYEDKSKV-----YLVMEL--VTGGELFDRIVEKGSYTEKDASHLIR 150
                     |.|||.|...:.:.:..     .|::||  |:..||..|...:| ::.....|..|
Zfish    77 ---------HKNIVTLYGMFTNHNPFGVATHCLLLELLDVSVSELLVRASNQG-HSMWLIQHCAR 131

  Fly   151 QILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSGIMATACG--------T 207
            .:|||:.::|.:|.||.||||.|:|:.:.|:..|::  |||||..|         |        |
Zfish   132 DVLEALTFLHREGFVHADLKPRNVLWSADDECFKLI--DFGLSFKE---------GHQDVKYIQT 185

  Fly   208 PGYVAPEVLAQKPYGK-----------AVDVWSIGVI 233
            .||.|||...|....:           |||:||:|::
Zfish   186 DGYRAPEAELQNSLAQAGVESDSGCTTAVDLWSLGIV 222

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	64/232 (28%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	64/232 (28%)
uhmk1	NP_001070127.1	STKc_KIS	23..299	CDD:270922	64/232 (28%)
		S_TKc	24..295	CDD:214567	64/232 (28%)
		RRM_UHMK1	309..396	CDD:240911
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0032
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900