DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKI and dclk1

DIOPT Version :9

Sequence 1:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	XP_012812605.1	Gene:	dclk1 / 733926	XenbaseID:	XB-GENE-960590	Length:	753	Species:	Xenopus tropicalis

Alignment Length:	366	Identity:	144/366 - (39%)
Similarity:	211/366 - (57%)	Gaps:	35/366 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 VSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLENEIRVLRRFSANH 89
            |||.|:|.:...:|.|.|:.|:....: |.|..:|:|||:|...:|||..::||:.:||
Frog   397 VSISERYKVGRTIGDGNFAIVKECIER-STGREYALKIINKSKCRGKEHMIQNEVSILR------ 454

  Fly    90 FDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIRQILE 154
                     |:.|||||.|:|..:..|::|||||||.||:|||.|.....|||:||:.::..::.
Frog   455 ---------RVKHPNIVLLIEEMDMPSELYLVMELVKGGDLFDAITSTNKYTERDANGMLYNLMS 510

  Fly   155 AVDYMHEQGVVHRDLKPENLLYYSPDDDSK-IMISDFGLSKMEDSGIMATACGTPGYVAPEVLAQ 218
            |:.|:|...:||||:||||||.|...|.|| :.:.||||:.:.| |.:.|.||||.|||||::|:
Frog   511 AIKYLHSLNIVHRDIKPENLLVYEHQDGSKSLKLGDFGLATVVD-GPLYTVCGTPTYVAPEIIAE 574

  Fly   219 KPYGKAVDVWSIGVISYILLCGYPPFYDENDAN--LFAQILKGDFEFDSPYWDEISESAKHFIKN 281
            ..||..||:|:.|||:||||||:|||....|..  ||.|||.|..:|.|||||.:|:|||..|..
Frog   575 TGYGLKVDIWAAGVITYILLCGFPPFRGSGDDQEVLFDQILMGHMDFPSPYWDNVSDSAKELITM 639

  Fly   282 LMCVTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLKKNF---AKSRWKQA---YYAATVI- 339
            ::.|.|::||:..:.|.|.|::.:.........:|:.::||:|   .|.....|   ..|.|.:
Frog   640 MLQVDVDQRYSALKVLEHPWVNDDGLPENEYPLSVAGKIKKHFNTGPKPNCNSAGVNVIATTALD 704

  Fly   340 --RQMQRMALNSNSNANFDSS------NSSNQDSTTPTAAT 372
              ||:.|...|.:....|.|.      ||.::|.:..::.|
Frog   705 KERQVFRRRRNQDVRYRFGSHQAAPEFNSESEDYSPSSSET 745

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	123/276 (45%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	121/273 (44%)
dclk1	XP_012812605.1	DCX1_DCLK1	55..143	CDD:340660
		DCX2	182..265	CDD:340589
		STKc_DCKL1	396..663	CDD:271085	126/282 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920