DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKI and si:ch211-27e6.1

DIOPT Version :9

Sequence 1:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	XP_009305164.3	Gene:	si:ch211-27e6.1 / 566628	ZFINID:	ZDB-GENE-130530-569	Length:	434	Species:	Danio rerio

Alignment Length:	440	Identity:	147/440 - (33%)
Similarity:	229/440 - (52%)	Gaps:	97/440 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LFGKKDS-GKKAKAKDL--------------KELNKQVSIEE---------------KYNLHGLL 37
            :|.|::| |:|...|..              :||:.:.:||.               :|.:..|:
Zfish    38 IFNKQESEGEKCVEKQQTGLWKKRSDGGASGEELHLEENIENRNAKFRAKFDPRVTARYEIQALI 102

  Fly    38 GTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLENEIRVLRRFSANHFDGKCLNGTRLTH 102
            |.|:||.|..||.|.: .:.||:|::|.:|.:|. ||.:.|:||||               |:.|
Zfish   103 GRGSFSRVVRAEHKQT-HQPFAIKLLDLRAPEGL-ESCQAELRVLR---------------RVNH 150

  Fly   103 PNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHR 167
            |||::|.|.::...:||||:||.|||||.:|::.:|::.|:||:..:..:...:.|:|..||:||
Zfish   151 PNIIRLTEVFQTPHRVYLVLELATGGELLERVLSRGTFRERDATKALLMVTSGLAYLHNLGVIHR 215

  Fly   168 DLKPENLLYYSPDDDSKIMISDFGLS---------------KMEDSG-IMATACGTPGYVAPEVL 216
            ||||||||||.|..||:::|:||||:               .:|:.| .:.|.||||.|:|||:|
Zfish   216 DLKPENLLYYHPGQDSRLIITDFGLACWDKSIQRDDLELTVGLEEKGWALRTLCGTPEYLAPEML 280

  Fly   217 AQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKHFIKN 281
            |::..|:|||:|::|:|:|:||.|..||...:.|.||..||||.:.|....|..:|...|.||..
Zfish   281 ARRGCGRAVDMWALGIITYVLLSGSLPFDHSSRAKLFRAILKGSYSFHGEPWRSVSSLGKGFING 345

  Fly   282 LMCVTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLKKNFAKSRWKQAYYAATVIRQMQRMA 346
            |:.|..|:|.:.::||.|.|:....|.|.|          ||..:|          :.|.:||.|
Zfish   346 LLTVVPEQRMSAEEALHHPWLVNMAACSSN----------KNLQRS----------ISRNLQRRA 390

  Fly   347 LNSNSNANFDSSNSSNQDSTTPTAATGAWTSNVLSSQQSVQSHAQEMNKS 396
                          |...|..|::|:|:..|...||:..:::.::..|.|
Zfish   391 --------------SRTSSRCPSSASGSQASRSSSSRLGLRNGSRCQNIS 426

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	118/304 (39%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	116/286 (41%)
si:ch211-27e6.1	XP_009305164.3	PKc_like	94..366	CDD:328722	116/288 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	1	1.000	-	-		FOG0000163
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.920