DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CaMKI and camkvl

DIOPT Version :9

Sequence 1:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster
Sequence 2:	XP_021325614.1	Gene:	camkvl / 553431	ZFINID:	ZDB-GENE-090311-58	Length:	762	Species:	Danio rerio

Alignment Length:	399	Identity:	147/399 - (36%)
Similarity:	232/399 - (58%)	Gaps:	32/399 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 KDLKELNKQVSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDKKALKGKEESLENEIR 80
            :|.:..|....|.:||.:..:|....|.|:.|.:.:.:...:...|.:.|...|.: ::.:|||.
Zfish    15 RDGRTYNSLSDITDKYEIGQVLKAKEFCELCLVKERQTDKVYVCKKFLKKDGRKVR-KAAKNEIM 78

  Fly    81 VLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDA 145
            :|:               .:.||||:||::.:|.:.:.:::.||.|||::||.|:::|:|||:||
Zfish    79 ILK---------------MVKHPNILQLIDAFETRKEFFIIQELATGGDVFDWILDQGNYTERDA 128

  Fly   146 SHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLSKMEDSGIMATACGTPGY 210
            :::|||:||||.|:|...:|||:||.|||:||...:.:|:::.||.||:.| :|.:...||||.|
Zfish   129 ANVIRQVLEAVAYLHSLNIVHRNLKLENLMYYRESNHNKVVLRDFYLSRFE-NGSITEPCGTPEY 192

  Fly   211 VAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDAN--------LFAQILKGDFEFDSPY 267
            :||||:|:..||:.||.|::|||.||||.|.||||||.:..        :|.:|:.|:|||||||
Zfish   193 LAPEVVARHRYGRPVDCWAVGVIMYILLSGNPPFYDETEEENTDMHNRIIFCRIVGGEFEFDSPY 257

  Fly   268 WDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLKKNFAKSRWKQA 332
            ||:||.:||..:...|.|....|.|.:.||.|.||:||.||.:|:...|..|.:|||||::|::.
Zfish   258 WDDISPAAKELVCRFMEVDQMLRITAQDALTHEWIAGNGASEKNLKEGVCAQFEKNFAKAKWREL 322

  Fly   333 YYAATVIRQMQRMA---LNSNSNA---NFDSSNSSNQDSTTPTAATGAWTSNVLSSQQSVQSHAQ 391
            ..|..|...|||:.   :.|:..|   ..:...:...|.......:|..::..:|.:.||:|...
Zfish   323 KKAIRVTTFMQRLRATDIGSSDGAVEGQAEGVKADGLDGKGIQTDSGGVSAGSVSHEVSVESRPT 387

  Fly   392 EMNKSGGST 400
            | |:..|.|
Zfish   388 E-NQEAGQT 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	113/281 (40%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	111/278 (40%)
camkvl	XP_021325614.1	PKc_like	28..292	CDD:328722	112/280 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24347
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	3.020