Protein Alignment CaMKI and stk33

DIOPT Version :10

• Sequence 1: NP_524622.1
• Gene: CaMKI / 43792
• FlyBaseID: FBgn0016126
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: XP_031755965.1
• Gene: stk33 / 549733
• XenbaseID: XB-GENE-940061
• Length: 480
• Species: Xenopus tropicalis
• Alignment Length: 432
• Identity: 121/432 - (28%)
• Similarity: 206/432 - (47%)
• Gaps: 49/432 - (11%)

  Fly     1 MPLFGKKDSGKKAKAKDLKELNKQVSIEEKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIIDK 65
            ||....:|:..::|....: ::.:.:|::.|.....||.|:|..|..|..|::..:....|:..:
 Frog    13 MPSQWSRDNSAESKVPHTR-MDDEAAIQQIYTFGKKLGQGSFGVVIEATHKETATKWAMKKVNRE 76

  Fly    66 KALKGKEESLENEIRVLRRFSANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGEL 130
            ||.....:.||.|:.:|:               |:.|.:|:.|.|.:|...::|||.||..||||
 Frog    77 KAGSSAVKLLEREVSILK---------------RVKHDHIIHLEEVFETPKRMYLVTELCEGGEL 126

  Fly   131 FDRIVEKGSYTEKDASHLIRQILEAVDYMHEQGVVHRDLKPENLLYYSPD--DDSK----IMISD 189
            .:.:..|...:|.:..|:||.:..|:.|:|.:|:||||||.||:|..|.|  |:.:    |.::|
 Frog   127 REILHRKKCLSEAETRHVIRSLGSAIAYLHRKGIVHRDLKLENILVKSNDGADNEELILNIKVTD 191

  Fly   190 FGLSKMEDSGI-----MATACGTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDEND 249
            |||: ::..|:     :.:.||||.|:||||:....|.:..|:||.|||.|:||.|.|||...::
 Frog   192 FGLA-VQKGGVGSENMLQSTCGTPIYMAPEVINDHDYSQQCDIWSTGVIMYMLLSGNPPFMAGSE 255

  Fly   250 ANLFAQILKGDFEFDSPYWDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWISGNEA------- 307
            ..||..|.:|:.:|....|..||.:||..::.|:.|....|.|..:.|.:.||:|...
 Frog   256 EKLFEDIRRGELKFSDAVWQGISNAAKDVLQRLLKVDPAHRITANELLDNPWITGETTLVQRPTN 320

  Fly   308 ------SSRNIHGTVSEQLKKNFAKSRWKQAYYAATVIRQMQRMALNSNSNANFDS-SNSSNQDS 365
                  :.:|:.....:.|.:|.............||..:....:.|..|....|: ::||:...
 Frog   321 VLELMNAWKNLDADELDHLDENSNGLSLAHLIDIPTVEERASPASSNGTSEMGLDTETDSSSSKP 385

  Fly   366 TTPT-------AATGAWTSNVLSSQQSVQSHAQEMNKSGGST 400
            :|||       ..:.:.||..:..:.|....|...:.:|.::
 Frog   386 STPTNQVTKKKTVSSSLTSRTVKKKSSTLKPASSPSTNGNTS 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	96/284 (34%)
stk33	XP_031755965.1	Protein Kinases, catalytic domain	40..308	CDD:473864	95/283 (34%)