Protein Alignment CaMKI and PHKG1

DIOPT Version :10

• Sequence 1: NP_524622.1
• Gene: CaMKI / 43792
• FlyBaseID: FBgn0016126
• Length: 405
• Species: Drosophila melanogaster
• Sequence 2: XP_016867813.1
• Gene: PHKG1 / 5260
• HGNCID: 8930
• Length: 432
• Species: Homo sapiens
• Alignment Length: 331
• Identity: 105/331 - (31%)
• Similarity: 159/331 - (48%)
• Gaps: 78/331 - (23%)

  Fly    29 EKYNLHGLLGTGAFSEVRLAESKDSPGEHFAVKIID--------KKALKGKEESLENEIRVLRRF 85
            |.|....:||.|..|.||....|.: .:.:|||:||        .:.::...|:...|:.:||:.
Human    18 ENYEPKEILGRGVSSVVRRCIHKPT-SQEYAVKVIDVTGGGSFSPEEVRELREATLKEVDILRKV 81

  Fly    86 SANHFDGKCLNGTRLTHPNIVQLLETYEDKSKVYLVMELVTGGELFDRIVEKGSYTEKDASHLIR 150
            |.              ||||:||.:|||..:..:||.:|:..|||||.:.||.:.:||:...::|
Human    82 SG--------------HPNIIQLKDTYETNTFFFLVFDLMKRGELFDYLTEKVTLSEKETRKIMR 132

  Fly   151 QILEAVDYMHEQGVVHRDLKPENLLYYSPDDDSKIMISDFGLS---------KMEDS-------- 198
            .:||.:..:|:..:|||||||||:|.   ||:..|.::|||.|         ::|..
Human   133 ALLEVICTLHKLNIVHRDLKPENILL---DDNMNIKLTDFGFSCQLEPGERLRVETGFHHVGQAG 194

  Fly   199 -----------------------------GIMATACGTPGYVAPEVLA------QKPYGKAVDVW 228
                                         ||.:..||||.|:|||::.      ...|||.||:|
Human   195 LELLTLRSARLGLPKCCDYRREPPCPAGLGISSEVCGTPSYLAPEIIECSMNEDHPGYGKEVDMW 259

  Fly   229 SIGVISYILLCGYPPFYDENDANLFAQILKGDFEFDSPYWDEISESAKHFIKNLMCVTVEKRYTC 293
            |.|||.|.||.|.|||:......:...|:.|:::|.||.||:.|::.|..:...:.|..:.|||.
Human   260 STGVIMYTLLAGSPPFWHRKQMLMLRMIMSGNYQFGSPEWDDYSDTVKDLVSRFLVVQPQNRYTA 324

  Fly   294 KQALGH 299
            ::||.|
Human   325 EEALAH 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	105/331 (32%)
PHKG1	XP_016867813.1	Protein Kinases, catalytic domain	16..336	CDD:473864	105/331 (32%)